Anticorps IRF-1 (B-1): sc-137061
- L'Anticorps IRF-1 (B-1) est un monoclonal de souris IgG1 κ, cité dans 8 publications, fourni en 200 µg/ml
- dirigé contre les acides aminés 121-325 de IRF-1 d'origine human
- recommandé pour la détection de IRF-1 d'origine human par WB, IP, IF et ELISA
- Réactifs TransCruz pour une application en ChIP (sc-137061 X, 200 µg/0.1 ml)
- Voir IRF-1 (E-4): sc-514544 pour d'autres anticorps conjugués IRF-1, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
- m-IgG Fc BP-HRP et 1 BP-HRP">m-IgG1 BP-HRP sont les réactifs de détection secondaire préférés pour IRF-1 Antibody (B-1) for WB applications. Ces réactifs sont désormais proposés en lots avec IRF-1 Antibody (B-1)(voir les informations de commande ci-dessous).
Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-α and β) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-α and interferon-β genes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth; overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3γ p48 (a component of the ISGF-3 complex) and IFN consensus sequence-binding protein (ICSBP).
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps IRF-1 (B-1) | sc-137061 | 200 µg/ml | RMB2377.00 | |||
IRF-1 (B-1): m-IgG Fc BP-HRP Kit | sc-539925 | 200 µg Ab; 10 µg BP | RMB2662.00 | |||
IRF-1 (B-1): m-IgG1 BP-HRP Kit | sc-541791 | 200 µg Ab; 20 µg BP | RMB2662.00 | |||
Anticorps IRF-1 (B-1) X | sc-137061 X | 200 µg/0.1 ml | RMB2377.00 |