Date published: 2025-9-17

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Anticorps hnRNP L (D-5): sc-48391

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Fiches techniques
  • L'Anticorps hnRNP L (D-5) est un monoclonal de souris IgG1 κ, cité dans 5 publications, fourni en 200 µg/ml
  • dirigé contre les acides aminés 257-334 de hnRNP L d'origine human
  • recommandé pour la détection de hnRNP L d'origine mouse, rat et human par WB, IP, IF, IHC(P) et ELISA; également réactif avec d'autres espèces, dont et equine, canine and bovine
  • Voir hnRNP L (4D11): sc-32317 pour d'autres anticorps conjugués hnRNP L, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP et m-IgGκ BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps hnRNP L (D-5) pour des applications de WB and IHC(P). Ces réactifs sont maintenant proposés en kit avec l'anticorps hnRNP L (D-5) (voir Informations pour la commande ci-dessous).

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of polypeptides that contribute to mRNA transcription, pre-mRNA processing as well as mature mRNA transport to the cytoplasm and translation. They also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA polymerase II. There are approximately 20 known hnRNP proteins, and their complexes are the major constituents of the spliceosome. The majority of hnRNP proteins components are localized to the nucleus; however some shuttle between the nucleus and the cytoplasm. hnRNP I, also designated polypyrimidine tract-binding protein (PTB), and its homolog hnRNP L bind to the 3' end of introns to modulate alternative splicing mechanisms of pre-mRNAs in normal cells and the translation of several viruses, including hepatitis C virus (HCV). The human hnRNP I gene encodes a protein that is localized in the nucleoplasm. hnRNP L like hnRNP I, is also localized in the nucleoplasm.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps hnRNP L (D-5)

sc-48391
200 µg/ml
$316.00

hnRNP L (D-5): m-IgG Fc BP-HRP Kit

sc-536825
200 µg Ab; 10 µg BP
$354.00

hnRNP L (D-5): m-IgGκ BP-HRP Kit

sc-533992
200 µg Ab; 40 µg BP
$354.00

hnRNP L (D-5): m-IgG1 BP-HRP Kit

sc-544843
200 µg Ab; 20 µg BP
$354.00

Can hnRNP L (D-5): sc-48391 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Posée par: Cweed
Thank you for your question. Yes, hnRNP L (D-5): sc-48391 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Répondue par: Technical Support
Date de publication: 2017-02-27
  • y_2025, m_9, d_16, h_9CST
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Rated 5 de 5 de par The antibody works well for Western blottingThe antibody works well for Western blotting detecting endogenous hnRNP L from SHP-77 and HeLa whole cell lysates and Jurkat and NIH/3T3 nuclear extracts.
Date de publication: 2015-04-15
Rated 2 de 5 de par Lots of background and multiple bands detectedLots of background and multiple bands detected with transfected lysate -SCBT QC
Date de publication: 2015-04-05
Rated 5 de 5 de par Robust mmunoperoxidase staining of formalin fixedRobust mmunoperoxidase staining of formalin fixed, paraffin-embedded human duodenum tissue showing nuclear staining of glandular cells. - SCBT QC
Date de publication: 2015-03-11
Rated 5 de 5 de par Great immunofluorescence staining of methanolGreat immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization. - SCBT QC
Date de publication: 2015-02-11
  • y_2025, m_9, d_16, h_9
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Anticorps hnRNP L (D-5) est évalué 4.3 de 5 de 4.
  • y_2025, m_9, d_16, h_9
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