ACCÈS RAPIDE AUX LIENS
VOIR ÉGALEMENT...
The HIRIP3 (HIRA interacting protein 3) locus encodes for a 556 amino acid protein that directly interacts with the HIRA histone chaperone. It also interacts weakly with core histones, Histone H2B and Histone H3. HIRIP3 is a heavily phosphorylated nuclear protein and it is found throughout the cell cycle. It is phosphorylated by casein kinase II. HIRIP3 may play a role in chromatin function and histone metabolism. A region (approximately 60 amino acids in length) at the C-terminus of HIRIP3 is highly conserved among vertebrates and it contains residues that are invariantly charged, polar, and hydrophobic. Two isoforms of HIRIP3 exists due to alternative splicing. Isoform 1 is predominately expressed in skeletal muscles and isoform 2 is expressed in the liver and the heart. Human HIRA homologs are thought to be responsible for the DiGeorge syndrome and related developmental disorders.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps HIRIP3 (2415C2a) | sc-81096 | 100 µg/ml | RMB2504.00 |