Anticorps GCAP1 (E-5): sc-390695
- L'Anticorps GCAP1 (E-5) est un monoclonal de souris mouse IgG1 κ (chaîne légère kappa) fourni en 200 µg/ml
- dirigé contre les acides aminés 1-201 correspondant à la séquence totale de GCAP1 d'origine human
- recommandé pour la détection de GCAP1 d'origine mouse, rat et human par WB, IP, IF et ELISA
- m-IgG Fc BP-HRP et m-IgG1 BP-HRP sont les réactifs de détection secondaire préférés pour GCAP1 Antibody (E-5) for WB applications. Ces réactifs sont désormais proposés en lots avec GCAP1 Antibody (E-5)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
The intracellular stimulation of guanylate cyclase (GC) by calcium, a key event in the recovery of the dark state of rod photoreceptors after exposure to light, is mediated by guanylate cyclase-activating protein (GCAP1). GCAPs are calcium-binding proteins belonging to the calmodulin superfamily. GCAP1 is a calcium-binding protein that stimulates synthesis of c-GMP in photoreceptors. GCAP1 is present in rod and cone photoreceptor outer segments where phototransduction occurs. In contrast to other calcium-binding proteins from the calmodulin superfamily, the calcium-free form of GCAP1 stimulates the effector enzyme. By molecular cloning of human and mouse GCAP cDNA, the known mammalian GCAPs are found to be more than 90% similar, consisting of 201 to 205 amino acids, and containing three identically conserved calcium-binding sites. A related protein, GCAP2, is detectable only in the retina and results from a gene duplication event.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps GCAP1 (E-5) | sc-390695 | 200 µg/ml | RMB2422.00 | |||
GCAP1 (E-5): m-IgG Fc BP-HRP Kit | sc-540835 | 200 µg Ab; 10 µg BP | RMB2715.00 | |||
GCAP1 (E-5): m-IgG1 BP-HRP Kit | sc-542403 | 200 µg Ab; 20 µg BP | RMB2715.00 |