Date published: 2025-10-10

021-6093-6350

SCBT Portrait Logo
Seach Input

DGCR6L 抑制因子

DDX26B Inhibitors constitute a specific class of chemical compounds designed to selectively impede the activity of the DDX26B enzyme. DDX26B, also known as DEAD-box helicase 26B, belongs to the broader family of DEAD-box helicases, which are involved in RNA metabolism and contribute to various aspects of RNA processing, including transcription, splicing, and translation. The development of inhibitors targeting DDX26B is pivotal for scientific exploration, offering specialized tools to elucidate the molecular functions and regulatory roles associated with this particular helicase. As a member of the DEAD-box helicase family, DDX26B likely plays a role in unwinding RNA secondary structures, facilitating RNA-protein interactions, and modulating the dynamic landscape of cellular RNA processing events.

The synthesis and optimization of DDX26B inhibitors necessitate a thorough understanding of the enzyme's structural features and its interactions within cellular pathways. These inhibitors are meticulously designed for specificity, aiming to selectively bind to key regions of DDX26B and interfere with its normal helicase activities. By utilizing DDX26B inhibitors in experimental settings, researchers can investigate the consequences of enzyme inhibition on RNA processing dynamics, shedding light on the specific substrates and molecular pathways governed by DDX26B. The study of DDX26B inhibitors contributes to the broader comprehension of cellular RNA metabolism, providing insights into the intricate molecular mechanisms that regulate gene expression and RNA-related processes in cells.

関連項目

产品名称CAS #产品编号数量价格应用排名

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
¥2933.00
¥11609.00
26
(2)

α-Amanitin 可抑制 RNA 聚合酶 II,阻碍转录并阻止 DGCR6L mRNA 的合成。

Puromycin dihydrochloride

58-58-2sc-108071
sc-108071B
sc-108071C
sc-108071A
25 mg
250 mg
1 g
50 mg
¥451.00
¥2369.00
¥9206.00
¥733.00
394
(15)

嘌呤霉素会诱导蛋白质合成过早终止,影响翻译并降低 DGCR6L 水平。

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
¥824.00
¥2685.00
¥8089.00
¥28453.00
¥241660.00
53
(3)

放线菌素 C1 与 DNA 结合并抑制转录物,导致 DGCR6L 的表达减少。

Cordycepin

73-03-0sc-203902
10 mg
¥1117.00
5
(1)

虫草素会干扰 mRNA 合成,影响转录物,导致 DGCR6L 下调。

Flavopiridol Hydrochloride

131740-09-5sc-207687
10 mg
¥3509.00
(2)

黄酮哌啶醇是一种细胞周期蛋白依赖性激酶抑制剂,可阻止 RNA 聚合酶 II 的磷酸化并抑制 DGCR6L 的转录。

Ellipticine

519-23-3sc-200878
sc-200878A
10 mg
50 mg
¥1602.00
¥6295.00
4
(1)

鞣花碱插入 DNA 中,抑制转录物,导致 DGCR6L 的表达减少。

Streptonigrin

3930-19-6sc-500892
sc-500892A
1 mg
5 mg
¥1151.00
¥4028.00
1
(1)

链霉菌素能抑制细菌 RNA 聚合酶,通过干扰转录物间接影响 DGCR6L 的表达。

Mycophenolic acid

24280-93-1sc-200110
sc-200110A
100 mg
500 mg
¥767.00
¥2945.00
8
(1)

霉酚酸抑制单磷酸肌苷脱氢酶,通过破坏嘌呤合成间接影响 DGCR6L 的表达。

Blasticidin S Hydrochloride

3513-03-9sc-204655A
sc-204655
25 mg
100 mg
¥4062.00
¥5359.00
20
(2)

Blasticidin S 可诱导翻译过程中的过早终止子,抑制蛋白质合成并降低 DGCR6L 水平。