Whittles et al (2002) ZM323881, a novel inhibitor of vascular endothelial growth factor-receptor-2 tyrosine kinase activity. Microcirculation 9 513. Endo et al (2003) Selective inhibition of vascular endothelial growth factor receptor-2 (VEGFR-2) identifies a central role for VEGFR-2 in human aortic endothelial cell responses to VEGF. J.Recept.Signal Transduct.Res. 23 239.
抑制剂:
EGFR, Flg, Flk-1, PDGFR-beta, 和 Tyrosine Kinase.
外观 :
Powder
物理状态 :
Solid
溶解度 :
Soluble in DMSO (50 mM), water (<1 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C).