Date published: 2025-9-7

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Z39Ig 抗体 (6H8): sc-53977

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说明书
  • Z39Ig 抗体 6H8 是小鼠单克隆 IgG1 κ,Z39Ig抗体, 在6篇文献中引用,规格为200 µg/ml
  • 针对Z39Ig-转染的HeLa细胞(源自human)
  • Z39Ig 抗体 (6H8) 推荐用于WB, IP, IF 和 FCM,检测human 来源的 Z39Ig
  • 抗Z39Ig抗体(6H8)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取Z39Ig (6H8): sc-53977免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 目前,我们还没有完成Z39Ig 抗体 (6H8)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

Z39Ig 抗体(6H8)是一种小鼠单克隆 IgG1 kappa 轻链抗体,可通过免疫印迹(WB)、免疫荧光(IF)和流式细胞术(FCM)检测人源 Z39Ig 蛋白。抗 Z39Ig 抗体 (6H8) 有非共轭型和多种共轭型,包括琼脂糖、辣根过氧化物酶 (HRP)、藻红蛋白 (PE)、异硫氰酸荧光素 (FITC) 和多种 Alexa Fluor® 共轭物。Z39Ig 是免疫球蛋白超家族细胞粘附分子 (CAM) 的成员,在介导细胞-细胞和细胞-基质的相互作用中起着至关重要的作用。这些相互作用对许多生物过程至关重要,包括细胞生长、分化、免疫反应以及癌症转移。Z39Ig 主要在人类胎儿组织、成人肺部和胎盘中表达,突显了它在发育过程和组织稳态中的重要性。Z39Ig 定位于人类 X 染色体的近中心区域,Z39Ig 的表达对于胚胎的正常形态发育和神经元突触粘附至关重要,而这对于学习和记忆至关重要。包括 Z39Ig 在内的 CAM 基因的失调或突变与多种癌症有关,影响肿瘤的生长和转移,因此 Z39Ig 成为癌症生物学研究和治疗干预的重要靶点。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Z39Ig 抗体 (6H8) 参考文献:

  1. 克隆位于人类 X 染色体上的具有免疫球蛋白样结构域的新型基因 Z39Ig。  |  Langnaese, K., et al. 2000. Biochim Biophys Acta. 1492: 522-5. PMID: 11004523
  2. Z39Ig 与活化的巨噬细胞基因共同表达。  |  Walker, MG. 2002. Biochim Biophys Acta. 1574: 387-90. PMID: 11997108
  3. 通过 cDNA 减法和芯片分析确定人类树突状细胞亚群中差异表达的基因。  |  Ahn, JH., et al. 2002. Blood. 100: 1742-54. PMID: 12176896
  4. 免疫球蛋白超家族成员 Z39Ig 蛋白特异性单克隆抗体的特征。  |  Kim, JK., et al. 2005. Immunol Lett. 99: 153-61. PMID: 16009265
  5. CRIg:巨噬细胞吞噬循环病原体所需的补体受体。  |  Helmy, KY., et al. 2006. Cell. 124: 915-27. PMID: 16530040
  6. Z39Ig 在巨噬细胞上表达,可介导关节炎和动脉粥样硬化的炎症反应。  |  Lee, MY., et al. 2006. J Leukoc Biol. 80: 922-8. PMID: 16882875
  7. 成为或不成为 B7.  |  Zang, X. and Allison, JP. 2006. J Clin Invest. 116: 2590-3. PMID: 17016555
  8. VSIG4 是一种 B7 家族相关蛋白,是 T 细胞活化的负调控因子。  |  Vogt, L., et al. 2006. J Clin Invest. 116: 2817-26. PMID: 17016562
  9. C3b 与 CRIg 复合物的结构使人们对补体激活的调控有了更深入的了解。  |  Wiesmann, C., et al. 2006. Nature. 444: 217-20. PMID: 17051150

订购信息

产品名称产品编号规格价格数量收藏夹

Z39Ig 抗体 (6H8)

sc-53977
200 µg/ml
RMB2377.00

Z39Ig (6H8): m-IgG Fc BP-HRP 套装

sc-551777
200 µg Ab; 10 µg BP
RMB2662.00

Z39Ig 抗体 (6H8) AC

sc-53977 AC
500 µg/ml, 25% agarose
RMB3129.00

Z39Ig 抗体 (6H8) HRP

sc-53977 HRP
200 µg/ml
RMB2377.00

Z39Ig 抗体 (6H8) FITC

sc-53977 FITC
200 µg/ml
RMB2482.00

Z39Ig 抗体 (6H8) PE

sc-53977 PE
200 µg/ml
RMB2580.00

Z39Ig 抗体 (6H8) Alexa Fluor® 488

sc-53977 AF488
200 µg/ml
RMB2685.00

Z39Ig 抗体 (6H8) Alexa Fluor® 546

sc-53977 AF546
200 µg/ml
RMB2685.00

Z39Ig 抗体 (6H8) Alexa Fluor® 594

sc-53977 AF594
200 µg/ml
RMB2685.00

Z39Ig 抗体 (6H8) Alexa Fluor® 647

sc-53977 AF647
200 µg/ml
RMB2685.00

Z39Ig 抗体 (6H8) Alexa Fluor® 680

sc-53977 AF680
200 µg/ml
RMB2685.00

Z39Ig 抗体 (6H8) Alexa Fluor® 790

sc-53977 AF790
200 µg/ml
RMB2685.00

Is this Antibody Cross reactive to mouse crig/Z39Ig?

Asked by: finlaycm
Thank you for your question. We have not yet tested this antibody, Z39Ig (6H8): sc-53977, in mouse samples so we do not recommend the antibody for detection of this species.
Answered by: Technical Support
Date published: 2017-12-19

Can Z39Ig (6H8): sc-53977 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: TinTin
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, Z39Ig (6H8): sc-53977 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Great for multiple applicationsAntibody has been used to detect Z39Ig in human neutrophils by Flow Cytometry, Confocal Microscopy, Bactericidal Assay, and Neutrophil Extracellular Traps Assay in published research. -SCBT QC
Date published: 2023-09-14
Rated 5 out of 5 by from Excellent antibodyWe tested this antibody in cell culture experiment.it worked beautifully.
Date published: 2017-12-12
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Z39Ig 抗体 (6H8) is rated 4.7 out of 5 by 3.
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