Date published: 2025-9-7

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WRP 抗体 (B-3): sc-514179

5.0(1)
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说明书
  • WRP抗体(B-3)是小鼠单克隆IgG2b (kappa轻链),规格为200 µg/ml
  • 特异性抗原位于human物种的WRP的内部区域内的氨基酸196-215之间
  • 推荐用于 mouse, rat 和 human 来源的WRP WB, IP, IF 和 ELISA检测
  • 2b BP-HRP">m-IgG2b BP-HRPm-IgGκ BP-HRP是WRP Antibody (B-3) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与WRP Antibody (B-3) 打包提供(请参阅下面的订购信息)。

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    関連項目

    WAVE相关的Rac GTP酶活化蛋白(WRP),也称为SLIT-ROBO Rho GTP酶活化蛋白3(srGAP3)和精神障碍活化GAP(MEGAP),是一种含有1个FCH结构域、1个Rho-GAP结构域和1个SH3结构域的1099个氨基酸的蛋白质。WRP在大脑中高度表达,在肾脏中表达水平较低,通过与Cdc42和Rac1的相互作用,在细胞迁移中发挥作用。Cdc42和Rac1是两种调节多步骤细胞迁移过程的细胞内信号蛋白。WRP下调Cdc42和Rac1的活性,从而损害肌动蛋白和微管动力学、突起的形成以及总细胞迁移。编码WRP的基因缺陷与重度特发性智力迟钝有关。由于选择性剪接事件,存在三种WRP异构体。

    仅限研究使用。不适用于诊断和治疗用途。

    订购信息

    产品名称产品编号规格价格数量收藏夹

    WRP 抗体 (B-3)

    sc-514179
    200 µg/ml
    RMB2377.00

    WRP (B-3): m-IgGκ BP-HRP 套装

    sc-536244
    200 µg Ab; 40 µg BP
    RMB2662.00

    WRP (B-3): m-IgG2b BP-HRP 套装

    sc-549528
    200 µg Ab; 10 µg BP
    RMB2662.00

    WRP (B-3) 中和勝肽

    sc-514179 P
    100 µg/0.5 ml
    RMB511.00

    What application is the blocking peptide sc-514179 P appropriate for?

    Asked by: Dr Ninau Qelp
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-03-01
    • y_2025, m_9, d_6, h_5CST
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    Rated 5 out of 5 by from Great Western blot data of WRP expression in SHGreat Western blot data of WRP expression in SH-SY5Y, IMR-32 and Caki-1 whole cell lysates. -SCBT QC
    Date published: 2014-02-23
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    WRP 抗体 (B-3) is rated 5.0 out of 5 by 1.
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