Date published: 2025-9-7

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WIP 抗体 (A-7): sc-271113

5.0(3)
寫評論提問

说明书
  • WIP抗体(A-7)是小鼠单克隆IgG2b κ, 在5篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的WIP的C-terminus附近的氨基酸178-205之间
  • 推荐用于 mouse, rat 和 human 来源的WIP WB, IP, IF, IHC(P) 和 ELISA检测
  • m-IgG2b BP-HRPm-IgGκ BP-HRP 是 WIP 抗体 (A-7) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与WIP 抗体 (A-7) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

威斯科特-奥尔德里奇综合征蛋白(WASP)的突变通常会导致T细胞和B细胞异常激活,从而引起免疫缺陷。由503个氨基酸组成的WASP相互作用蛋白(WIP)包含多个与肌动蛋白结合的结构域和几个推定的src同源结合结构域。WASP的前100个氨基酸与WIP的第377-503个氨基酸相互作用,而与WAS相关的大多数致病突变都发生在WASP的前100个氨基酸内。编码人类WIP的基因位于2号染色体p23.3-q24.3。人类B细胞系BJAB中WIP的过度表达会增加F-肌动蛋白含量和脑回状突起。尽管WIP和Vav在NF-AT/AP-1基因转录的调控中都有作用,但WIP-WASP复合物对于激活NF-AT/AP-1以维持T细胞的正常功能是必需的。功能失调的WIP-WASP复合物可能与WAS的免疫缺陷表型有关。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

WIP 抗体 (A-7)

sc-271113
200 µg/ml
RMB2377.00

WIP (A-7): m-IgGκ BP-HRP 套装

sc-534872
200 µg Ab; 40 µg BP
RMB2662.00

WIP (A-7): m-IgG2b BP-HRP 套装

sc-549309
200 µg Ab; 10 µg BP
RMB2662.00

WIP (A-7) 中和勝肽

sc-271113 P
100 µg/0.5 ml
RMB511.00

What application is the blocking peptide sc-271113 P appropriate for?

Asked by: Dr Ninau Qelp
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Excellent!I got this primary antibody one week ago, WIP expression in H460 and H358 whole cell lysate at 1:500 dilution.I got a sepcific and beautiful band.
Date published: 2017-11-03
Rated 5 out of 5 by from Works well for WB with human WIP transfectedWorks well for WB with human WIP transfected 293T whole cell lysate. -SCBT QC
Date published: 2015-05-24
Rated 5 out of 5 by from Beautiful immunoperoxidase cytoplasmic stainingBeautiful immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human tonsil tissue. -SCBT QC
Date published: 2015-01-08
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WIP 抗体 (A-7) is rated 5.0 out of 5 by 3.
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