Date published: 2025-9-6
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VEGF Antibody (VG-1) - Immunohistochemistry - Image 348041
血管内皮生长因子抗体 (VG-1): sc-53462. 福尔马林固定, 石蜡包埋的人肝组织的免疫过氧化物酶染色, 显示肝细胞的胞浆染色.
血管内皮生长因子抗体 (VG-1): sc-53462. 福尔马林固定, 石蜡包埋的人肝组织的免疫过氧化物酶染色, 显示肝细胞的胞浆染色.

VEGF 抗体 (VG-1): sc-53462

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寫評論提問

说明书
  • VEGF抗体(VG-1)是小鼠单克隆IgG1 κ, 在97篇文献中引用，规格为200 µg/ml
  • 免疫human物种的重组VEGF189
  • 抗-VEGF 抗体 (VG-1) 推荐用于 WB, IP, IF 和 IHC(P)，检测mouse, rat, human 和canine 来源的 121, 165 and 189 VEGF isoforms
  • 抗VEGF抗体（VG-1）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取VEGF (VG-1): sc-53462的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP 和 m-IgG1 BP-HRP 是 VEGF 抗体 (VG-1) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与VEGF 抗体 (VG-1) 组合成套装提供。 (请参阅下面的订购信息)。

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描述
基因信息
说明书与实验方案
研究信息

関連項目

此外 VEGF 抗体包括 EG-VEGF, VEGF-B, VEGF-C 和 VEGF-D

VEGF抗体（VG-1）是一种小鼠单克隆IgG1 kappa轻链抗体，可通过蛋白质印迹（WB）、免疫沉淀（IP）、免疫荧光（IF）和免疫组织化学检测小鼠、大鼠、人类和犬的血管内皮生长因子（VEGF）。抗VEGF抗体（VG-1）有非结合型和结合型两种，可与琼脂糖、辣根过氧化物酶（HRP）、藻红蛋白（PE）、异硫氰酸荧光素（FITC）和多种Alexa Fluor®染料结合。VEGF在血管生成中起着至关重要的作用，在胚胎发育和损伤反应期间形成新的血管，为组织提供营养和氧气。VEGF失调会导致多种病理状况，包括癌症，其中VEGF通过增加肿瘤微环境的血液供应来促进肿瘤生长和转移。VEGF存在多种同种型，包括VEGF121、VEGF165和VEGF189，它们通过不同的生物活性和受体结合亲和力进行选择性剪接。VEGF165是最丰富的同种型，与Flt-1和KDR受体相互作用，介导内皮细胞的增殖和迁移。VEGF在刺激血管生成方面的作用使其成为治疗癌症和血管异常增生疾病的关键靶标。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

VEGF 抗体 (VG-1) 参考文献:

  1. VEGF作为肿瘤血管成熟的抑制剂：对癌症治疗的影响。  |  Greenberg, JI. and Cheresh, DA. 2009. Expert Opin Biol Ther. 9: 1347-56. PMID: 19761418
  2. 肿瘤进展和靶向治疗中的VEGF。  |  Chekhonin, VP., et al. 2013. Curr Cancer Drug Targets. 13: 423-43. PMID: 23167597
  3. VEGF-A mRNA处理、稳定性和翻译：转录后水平基因表达复杂调控的范例。  |  Arcondéguy, T., et al. 2013. Nucleic Acids Res. 41: 7997-8010. PMID: 23851566
  4. 抗VEGF治疗的RNA干扰技术。  |  Chen, S., et al. 2014. Expert Opin Drug Deliv. 11: 1471-80. PMID: 24898870
  5. 病毒感染中VEGF上调及其可能的治疗意义。  |  Alkharsah, KR. 2018. Int J Mol Sci. 19: PMID: 29865171
  6. 血管内皮生长因子（VEGF）--正常和病理血管生成的关键因素。  |  Melincovici, CS., et al. 2018. Rom J Morphol Embryol. 59: 455-467. PMID: 30173249
  7. 靶向VEGF-神经丝蛋白相互作用：一种有前景的抗肿瘤策略。  |  Peng, K., et al. 2019. Drug Discov Today. 24: 656-664. PMID: 30315890
  8. VEGF在信号传导和疾病中的作用：超越发现和发展。  |  Apte, RS., et al. 2019. Cell. 176: 1248-1264. PMID: 30849371
  9. 玻璃体内抗VEGF药物与心血管风险。  |  Porta, M. and Striglia, E. 2020. Intern Emerg Med. 15: 199-210. PMID: 31848994
  10. VEGF过度表达的间充质干细胞可促进大鼠模拟阴道分娩后的尿道和阴道恢复。  |  Mori da Cunha, MGMC., et al. 2023. Sci Rep. 13: 8622. PMID: 37244975

订购信息

产品名称产品编号规格价格数量收藏夹

VEGF 抗体 (VG-1)

sc-53462
200 µg/ml
$316.00

VEGF (VG-1): m-IgG Fc BP-HRP 套装

sc-526815
200 µg Ab; 10 µg BP
$354.00

VEGF (VG-1): m-IgG1 BP-HRP 套装

sc-532188
200 µg Ab; 20 µg BP
$354.00

VEGF 抗体 (VG-1) AC

sc-53462 AC
500 µg/ml, 25% agarose
$416.00

VEGF 抗体 (VG-1) HRP

sc-53462 HRP
200 µg/ml
$316.00

VEGF 抗体 (VG-1) FITC

sc-53462 FITC
200 µg/ml
$330.00

VEGF 抗体 (VG-1) PE

sc-53462 PE
200 µg/ml
$343.00

VEGF 抗体 (VG-1) Alexa Fluor® 488

sc-53462 AF488
200 µg/ml
$357.00

VEGF 抗体 (VG-1) Alexa Fluor® 546

sc-53462 AF546
200 µg/ml
$357.00

VEGF 抗体 (VG-1) Alexa Fluor® 594

sc-53462 AF594
200 µg/ml
$357.00

VEGF 抗体 (VG-1) Alexa Fluor® 647

sc-53462 AF647
200 µg/ml
$357.00

VEGF 抗体 (VG-1) Alexa Fluor® 680

sc-53462 AF680
200 µg/ml
$357.00

VEGF 抗体 (VG-1) Alexa Fluor® 790

sc-53462 AF790
200 µg/ml
$357.00

Anticuerpo VEGF sc53462: Precio Tiempo de entrega Como realizar el pedido

Asked by: Laura Peña
Thank you for your question. For accurate availability, shipping and pricing information for VEGF sc-53462, please contact our European Customer Service team. You can reach them by phone at Toll Free: +49 6221 4503 0, by email at: [email protected] or by live chat directly on our website, www.scbt.com.
Answered by: Technical Service
Date published: 2025-01-12

Is VEGF Antibody (VG-1): sc-53462 available directly conjugated to HRP or fluorescent dyes?

Asked by: jenni
Thank you for your question. All requests for directly conjugated versions of this antibody should be directed to our Special Orders team at [email protected] Alternatively, consider using VEGF (C-1), which is available conjugated to agarose, HRP, FITC, PE, and more. (https://www.scbt.com/scbt/product/vegf-antibody-c-1)
Answered by: Technical Support 12
Date published: 2024-06-09
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Rated 5 out of 5 by from サンプル製品サンプル製品をもらい、VEGFのWBを行いました。 45kDa付近にVEGF165のバンドが綺麗に出ました。 購入したいと思います。
Date published: 2023-10-27
Rated 2 out of 5 by from Tested on different canine tissuesI tried this antibody on different canine FFPE tissues (granulation tissue, liver, thyroid), with different protocols and different concentrations, but the results were not satisfactory. Weak staining of thyroid.
Date published: 2022-06-08
Rated 1 out of 5 by from Non venuto in immunoistochimicaHo comprato questo anticorpo settembre scorso, testato a varie concentrazioni su fegato umano normale in paraffina, ma il risultato è stato deludente.
Date published: 2021-11-20
Rated 4 out of 5 by from Specific Westerns and IHC in rat INS-1 cells90 ug loads of rat insulinoma (INS-1) lysates were probed overnight and returned a single, moderately strong band of 21 kD. Also worked well for DAB-based IHC-P
Date published: 2019-05-22
Rated 5 out of 5 by from Nice strong bands!Worked great for WB... yielding nice strong bands when used at 1:200. Probably could use further dilutions with success! Also, I used this when probing mouse lysates.
Date published: 2018-03-23
Rated 5 out of 5 by from good signalworked well in the human kidney . We got obtained specific band is very clear and powerful signal.
Date published: 2017-05-09
Rated 5 out of 5 by from Great IHC dataVery strong antibody for IHC studies; also nice WB data
Date published: 2017-01-11
Rated 5 out of 5 by from Reliable Antibody, Great for IHCStrong, clear signal with little to no background. Beautiful tissue staining. Very reliable antibody good for several applications.
Date published: 2016-12-30
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VEGF 抗体 (VG-1) is rated 4.2 out of 5 by 13.
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