Date published: 2025-9-8

021-6093-6350

SCBT Portrait Logo
Seach Input

VCP 抗体 (E-4): sc-133125

5.0(2)
寫評論提問

说明书
  • VCP抗体(E-4)是小鼠单克隆IgG1 κ, 在4篇文献中引用,规格为200 µg/ml
  • 针对氨基酸687-806,在VCP的human起源的C-terminus处进行映射
  • 推荐用于 mouse, rat 和 human 来源的VCP WB, IP, IF 和 ELISA检测
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是VCP Antibody (E-4) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与VCP Antibody (E-4) 打包提供(请参阅下面的订购信息)。

快捷链接

関連項目

含缬氨酸蛋白(VCP),也称为TERA(过渡内质网ATP酶)或p97,是AAA ATP酶家族的成员,参与多种细胞活动。 VCP是酿酒酵母Cdc48的哺乳动物同源物,酿酒酵母Cdc48是酵母细胞有丝分裂完成所必需的蛋白质。 VCP被认为参与多种膜功能和细胞周期的调节。它与泛素化的IκB-α以及26S蛋白体结合,表明VCP在蛋白体介导的IκB-α降解中可能起作用。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

VCP 抗体 (E-4) 参考文献:

  1. 含缬氨酸蛋白在促进自噬以防止 Tau 聚合中的作用  |  Chinnathambi, S. and Gorantla, NV. 2021. Neuroscience. 476: 125-134. PMID: 34509548
  2. WIPI2 通过促进线粒体招募 VCP 来积极调节有丝分裂。  |  Lu, G., et al. 2022. Autophagy. 18: 2865-2879. PMID: 35389758
  3. 含缬氨酸蛋白(VCP/p97)负责典型猪瘟病毒的内吞转运。  |  Sun, RC., et al. 2022. Vet Microbiol. 272: 109511. PMID: 35849988
  4. 含缬氨酸蛋白病的基因型与表型相关性:一项回顾性突变中心研究。  |  Schiava, M., et al. 2022. J Neurol Neurosurg Psychiatry.. PMID: 35896379
  5. PTP4A2 通过使 VCP/p97 在 Tyr805 处去磷酸化来促进溶酶体吞噬。  |  Bai, Y., et al. 2023. Autophagy. 19: 1562-1581. PMID: 36300783
  6. AAA+ 合子 VCP 在细胞系统中分解 Tau 纤维并生成聚合种子。  |  Saha, I., et al. 2023. Nat Commun. 14: 560. PMID: 36732333
  7. 大鼠卵巢中含缬氨酸蛋白和小 VCP 交互蛋白的免疫表达。  |  Kartal, B., et al. 2023. Anat Histol Embryol. 52: 546-551. PMID: 36843060
  8. 与多系统蛋白病相关的含缬氨酸蛋白基因变异的临床分类。  |  Schiava, M., et al. 2023. Neurol Genet. 9: e200093. PMID: 37588275
  9. 含缬氨酸蛋白通过不同的机制成为心脏中 S-亚硝基化的靶标和媒介。  |  Shi, X., et al. 2024. Redox Biol. 72: 103166. PMID: 38685170
  10. 含缬氨酸的蛋白质:心血管疾病的潜在治疗目标。  |  Rakhe, N. and Bhatt, LK. 2024. Ageing Res Rev. 101: 102511. PMID: 39313037

订购信息

产品名称产品编号规格价格数量收藏夹

VCP 抗体 (E-4)

sc-133125
200 µg/ml
RMB2377.00

VCP (E-4): m-IgG Fc BP-HRP 套装

sc-537344
200 µg Ab; 10 µg BP
RMB2662.00

VCP (E-4): m-IgGκ BP-HRP 套装

sc-534587
200 µg Ab; 40 µg BP
RMB2662.00

VCP (E-4): m-IgG1 BP-HRP 套装

sc-545146
200 µg Ab; 20 µg BP
RMB2662.00

I need to use an antibody to detect the protein in samples of porcine origin. Do you know if VCP (E-4): sc-133125 mouse monoclonal antibody will work?

Asked by: Professor Griffin
Thank you for your inquiry. Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity. We are available by phone, e-mail or chat.
Answered by: Technical Support
Date published: 2017-03-01
  • y_2025, m_9, d_7, h_4CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_zh_CN, sid_133125, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 104ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from Strong specific band detected at expectedStrong specific band detected at expected molecular weight in HeLa, MDA-MB-231 and NIH/3T3 whole cell lysates and rat brain tissue extract. -SCBT QC
Date published: 2015-03-23
Rated 5 out of 5 by from WB publishable data with rat spinal cordsWB publishable data with rat spinal cords - SCBT Publication Review
Date published: 2014-06-08
  • y_2025, m_9, d_6, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_2
  • loc_zh_CN, sid_133125, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 8ms
  • REVIEWS, PRODUCT
VCP 抗体 (E-4) is rated 5.0 out of 5 by 2.
  • y_2025, m_9, d_6, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_2
  • loc_zh_CN, sid_133125, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 82ms
  • REVIEWS, PRODUCT