Date published: 2025-9-8

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USP10 抗体 (C-7): sc-365828

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说明书
  • USP10 抗体 C-7 是小鼠单克隆 IgG3 κ,USP10抗体, 在7篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的USP10的N-terminus附近的氨基酸67-95之间
  • 推荐用于 mouse, rat 和 human 来源的USP10 WB, IP, IF 和 ELISA检测; 也和以下物种反应,包括: porcine
  • 关于如何获取USP10 (C-7): sc-365828免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG3 BP-HRPm-IgGκ BP-HRP是USP10 Antibody (C-7) 适用于 WB 应用。 的首选辅助检测试剂,这些试剂现与USP10 Antibody (C-7) 打包提供(请参阅下面的订购信息)。

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関連項目

USP10抗体(C-7)是一种小鼠单克隆IgG3 kappa轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和酶联免疫吸附测定(ELISA)检测小鼠、大鼠和人类来源的USP10蛋白。抗USP10抗体(C-7)以非结合形式提供。USP10,也称为泛素特异性蛋白酶10或UBPO,是一种798个氨基酸的蛋白质,在泛素-蛋白酶体系统中起着至关重要的作用,而泛素-蛋白酶体系统对于调节各种细胞过程至关重要。USP10的主要功能之一是从泛素结合的底物上去除泛素,从而影响蛋白质的稳定性和活性。这种去泛素化活性在DNA结合雄激素受体复合物中尤为重要,USP10可以调节受体活性,从而影响基因表达。通过泛素化和去泛素化调节蛋白质降解和活性对于维持细胞内稳态和响应环境信号至关重要,这使得USP10在细胞信号通路中扮演着重要角色。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

USP10 抗体 (C-7) 参考文献:

  1. Ras-GAP SH3 结构域结合蛋白(G3BP)是一种新型人类泛素特异性蛋白酶 USP10 的调节剂。  |  Soncini, C., et al. 2001. Oncogene. 20: 3869-79. PMID: 11439350
  2. 人类和小鼠蛋白酶:基因组比较方法。  |  Puente, XS., et al. 2003. Nat Rev Genet. 4: 544-58. PMID: 12838346
  3. 泛素特异性蛋白酶 USP10 可调节雄激素受体的功能。  |  Faus, H., et al. 2005. Mol Cell Endocrinol. 245: 138-46. PMID: 16368182
  4. 胸苷酸合成酶(TS), 泛素特异性蛋白酶 10(USP10)和存活素的表达增加与多形性胶质母细胞瘤(GBM)的生存率低下有关。  |  Grunda, JM., et al. 2006. J Neurooncol. 80: 261-74. PMID: 16773218
  5. 通过 RFDD-PCR 和蛋白质组学方法观察乳腺癌组织中泛素特异性肽酶(USPs)和蛋白酶体亚基(PSs)基因和蛋白质的过度表达。  |  Deng, S., et al. 2007. Breast Cancer Res Treat. 104: 21-30. PMID: 17004105
  6. 去泛素化酶USP10保护胰腺癌细胞免受内质网应激。  |  Bhattacharya, U., et al. 2022. NPJ Precis Oncol. 6: 93. PMID: 36543867
  7. USP10 稳定 IGF2BP1 通过 CPT1A 以 m6A 依赖性方式促进乳腺癌转移。  |  Shi, J., et al. 2023. Int J Biol Sci. 19: 449-464. PMID: 36632454
  8. USP10通过增强TCF4蛋白的稳定性促进三阴性乳腺癌的发展。  |  Yang, JR., et al. 2023. Biochem Pharmacol. 218: 115864. PMID: 37863330
  9. 预测人类不明基因的编码序列。V. 通过分析来自人类细胞系 KG-1 的 cDNA 克隆,推导出 40 个新基因(KIAA0161-KIAA0200)的编码序列。  |  Nagase, T., et al. 1996. DNA Res. 3: 17-24. PMID: 8724849
  10. 去泛素化酶:一类新的生物调节剂。  |  D'Andrea, A. and Pellman, D. 1998. Crit Rev Biochem Mol Biol. 33: 337-52. PMID: 9827704

订购信息

产品名称产品编号规格价格数量收藏夹

USP10 抗体 (C-7)

sc-365828
200 µg/ml
RMB2377.00

USP10 (C-7): m-IgG Fc BP-HRP 套装

sc-551862
200 µg Ab; 10 µg BP
RMB2662.00

USP10 (C-7): m-IgGκ BP-HRP 套装

sc-522385
200 µg Ab, 40 µg BP
RMB2662.00

USP10 (C-7): m-IgG3 BP-HRP 套装

sc-550345
200 µg Ab; 40 µg BP
RMB2662.00

USP10 (C-7) 中和勝肽

sc-365828 P
100 µg/0.5 ml
RMB511.00

Can you send me a FREE 10 µg sample of USP10 (C-7): sc-365828. to test it before I order a whole tube? Best regards and thank you in advance. Rebekka Schairer

Asked by: Rebekka
Thank you for your question. Please contact Technical Service for more information on how to receive a 10 μg sample of our well characterized monoclonal antibody.
Answered by: Technical Support
Date published: 2018-12-05

What application is the blocking peptide sc-365828 P appropriate for?

Asked by: AbPolly
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 4 out of 5 by from Recommended for Western BlotI tested this antibody in HEK293 cells and obtained two bands at the expected mw, as reported by the supplier. Conditions: dilution 1:1000 in 0,5% milk, overnight at 4°C
Date published: 2024-10-07
Rated 4 out of 5 by from Funciona muy bienCompré este anticuerpo para WB el mes pasado y ha funcionado muy bien en distintos tipos celulares.
Date published: 2020-05-20
Rated 5 out of 5 by from Antibody worked well!!I used this antibody for IF and WB. It worked for both!!
Date published: 2017-11-30
Rated 5 out of 5 by from good antibody in western blot as well as IFWe used the antibody for WB and IF in human and mouse organoids as well as cell lines. Upon shRNA the band for Usp10 was significantly reduced.
Date published: 2017-11-07
Rated 5 out of 5 by from quite strong band for wb of rat protein1:500 diluted for wb of rat protein ,the band is quite strong !
Date published: 2017-09-27
Rated 5 out of 5 by from Effect in generalIt is not my want to strip, and then try other molecules.
Date published: 2017-07-05
Rated 5 out of 5 by from good specificityOne month ago I applied the antibody sc-365828(USP10), then I used it to do WB with 1:100 dilution in human lung cancer cell line, the protein loading was 15ug, the results showed good specificity
Date published: 2017-05-08
Rated 5 out of 5 by from Good Western blot data of USP10 expression in nonGood Western blot data of USP10 expression in non-transfected and mouse USP10 transfected 293T whole cell lysates. -SCBT QC
Date published: 2014-01-22
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USP10抗体 (C-7) is rated 4.8 out of 5 by 8.
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