Date published: 2025-9-8

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uricase 抗体 (C-11): sc-166214

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说明书
  • uricase抗体(C-11)是小鼠单克隆IgG2a λ uricase抗体, 在3篇文献中引用,规格为200 µg/ml
  • 免疫mouse物种的uricase的氨基酸1-303
  • uricase 抗体 (C-11) 推荐用于 WB, IP, IF 和 ELISA,检测mouse 和rat 来源的 uricase
  • 抗uricase抗体(C-11)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取uricase (C-11): sc-166214免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 2a BP-HRP">m-IgG2a BP-HRPm-IgGλ BP-HRP是uricase Antibody (C-11) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与uricase Antibody (C-11) 打包提供(请参阅下面的订购信息)。

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関連項目

uricase抗体(C-11)是一种IgG2a λ小鼠单克隆uricase抗体(也称为uricase抗体),可通过WB、IP、IF和ELISA检测小鼠和大鼠来源的uricase蛋白。uricase抗体(C-11)既可以作为非共轭的抗uricase抗体形式提供,也可以作为多种共轭形式的抗uricase抗体提供,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®共轭物。在大多数哺乳动物中,尿酸氧化酶(uricase)存在于肝脏中,而在其他组织中几乎或根本检测不到其活性。它与过氧化物酶体相关,并以四聚体的形式存在。人类和某些灵长类动物缺乏这种酶,该酶可催化尿酸氧化为尿囊素。人类莱施-尼汉综合征是一种罕见的神经和行为障碍,由嘌呤补救酶次黄嘌呤-鸟嘌呤磷酸核糖转移酶(HPRT)活性水平遗传性缺陷引起。完全缺乏HPRT但没有任何莱施-尼汉综合征症状的小鼠的发现,提高了这样一种可能性,即嘌呤代谢途径中缺乏尿酸酶活性可能导致人类出现观察到的神经症状。对人、小鼠和猪的序列进行比较表明,人类尿酸酶功能的丧失是由于突然的突变事件引起的。编码尿酸酶的基因定位于人类1号染色体p22上。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

uricase 抗体 (C-11) 参考文献:

  1. 人类尿酸氧化酶基因(UOX)在 1p22 的定位。  |  Yeldandi, AV., et al. 1992. Cytogenet Cell Genet. 61: 121-2. PMID: 1395718
  2. 拉斯布酶治疗急性高尿酸血症和肾功能障碍。  |  Ronco, C., et al. 2005. Contrib Nephrol. 147: 115-123. PMID: 15604611
  3. 尿酸盐氧化酶:主要结构和进化意义。  |  Wu, XW., et al. 1989. Proc Natl Acad Sci U S A. 86: 9412-6. PMID: 2594778
  4. 通过在小鼠体内引入 HPRT 突变,建立雷希─奈恩综合征的潜在动物模型。  |  Kuehn, MR., et al. Nature. 326: 295-8. PMID: 3029599
  5. 通过培养细胞的种系定植获得的 HPRT 缺失(莱希-尼汉)小鼠胚胎。  |  Hooper, M., et al. Nature. 326: 292-5. PMID: 3821905

订购信息

产品名称产品编号规格价格数量收藏夹

uricase 抗体 (C-11)

sc-166214
200 µg/ml
RMB2377.00

uricase (C-11): m-IgGλ BP-HRP 套装

sc-521535
200 µg Ab, 40 µg BP
RMB2662.00

uricase (C-11): m-IgG2a BP-HRP 套装

sc-546234
200 µg Ab; 10 µg BP
RMB2662.00

uricase 抗体 (C-11) AC

sc-166214 AC
500 µg/ml, 25% agarose
RMB3129.00

uricase 抗体 (C-11) HRP

sc-166214 HRP
200 µg/ml
RMB2377.00

uricase 抗体 (C-11) FITC

sc-166214 FITC
200 µg/ml
RMB2482.00

uricase 抗体 (C-11) PE

sc-166214 PE
200 µg/ml
RMB2580.00

uricase 抗体 (C-11) Alexa Fluor® 488

sc-166214 AF488
200 µg/ml
RMB2685.00

uricase 抗体 (C-11) Alexa Fluor® 546

sc-166214 AF546
200 µg/ml
RMB2685.00

uricase 抗体 (C-11) Alexa Fluor® 594

sc-166214 AF594
200 µg/ml
RMB2685.00

uricase 抗体 (C-11) Alexa Fluor® 647

sc-166214 AF647
200 µg/ml
RMB2685.00

uricase 抗体 (C-11) Alexa Fluor® 680

sc-166214 AF680
200 µg/ml
RMB2685.00

uricase 抗体 (C-11) Alexa Fluor® 790

sc-166214 AF790
200 µg/ml
RMB2685.00

What is the specific immunogen used to generate this antibody? Is it Candida, bacillus, or something else? Will it be reactive against candida Uricase?

Asked by: Soumen
Thank you for your question. For assistance please contact technical service . Please email [email protected] or call 800-457-3801.
Answered by: BlakeJ
Date published: 2025-02-07

What is the recommended fixation method for immunofluorescence staining with uricase (C-11): sc-166214 monoclonal antibody?

Asked by: Germaine
Thank you for your inquiry. We recommend fixing cells for 5 minutes in -10°C methanol and allowing to air dry. The full protocol can be viewed here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
Answered by: Technical Support
Date published: 2017-02-27
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Rated 5 out of 5 by from Great AbI have used this antibody for WB and have confirmed with my transgenic line. Works perfect!
Date published: 2017-09-26
Rated 5 out of 5 by from Produced superb immunofluorescence cytoplasmicProduced superb immunofluorescence cytoplasmic staining in methanol-fixed NIH/3T3 cells. -SCBT QC
Date published: 2015-01-11
Rated 5 out of 5 by from Good Western Blot data of uricase expressionGood Western Blot data of uricase expression in non-transfected and mouse uricase transfected 293T whole cell lysates. -SCBT QC
Date published: 2014-03-24
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uricase 抗体 (C-11) is rated 5.0 out of 5 by 3.
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