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TULP3 抗体 (H-10): sc-393411

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说明书
  • TULP3 抗体 H-10 是小鼠单克隆 IgG1 (kappa轻链),TULP3抗体,规格为200 µg/ml
  • 免疫原氨基酸序列1-300位于human物种的TULP3的N-terminus
  • TULP3 抗体 (H-10) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 TULP3
  • 抗TULP3抗体(H-10)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取TULP3 (H-10): sc-393411免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgGκ BP-HRP是TULP3 Antibody (H-10) 适用于 WB 应用。 的首选辅助检测试剂,这些试剂现与TULP3 Antibody (H-10) 打包提供(请参阅下面的订购信息)。

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    関連項目

    TULP3抗体(H-10)是一种IgG1 κ小鼠单克隆TULP3抗体(也被指定为TULP3抗体),可通过WB、IP、IF和ELISA技术检测小鼠、大鼠和人类来源的TULP3蛋白。TULP3抗体(H-10)既有非偶联型抗TULP3抗体形式,也有多种偶联形式的抗TULP3抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。小鼠Tub基因的突变逐渐导致肥胖,这与人类群体中观察到的迟发性肥胖非常相似。除了脂肪组织的过度沉积外,具有Tub表型的小鼠还会出现视网膜退化和神经性听力损失。已经确定了人类Tub基因的同源物,以及三种相关蛋白,分别称为Tubby样蛋白1(TULP1)、TULP2和TULP3。与TULP1和TULP2相比,TULP3具有更广泛的组织表达,并且在系统发育上与Tub比TULP1或TULP2更相似。TULP1特异性表达于视网膜,定位于已知参与视网膜色素变性的染色体区域,而TULP2定位于视杆-视锥细胞营养不良的最小间隔内。TULP3定位于人类染色体12p13,与小鼠TULP3具有69%的同源性。来自睾丸、卵巢、甲状腺和脊髓的人类RNA含有高度可检测的TULP3转录本水平。在视网膜中,TULP3特异性表达于内核层和神经节细胞层。TULP1、TULP2和TULP3可能构成一个独特的二元转录因子家族。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    TULP3 抗体 (H-10) 参考文献:

    1. 视网膜中管比基因家族成员(tub, Tulp1, 2 和 3)的细胞特异性表达。  |  Ikeda, S., et al. 1999. Invest Ophthalmol Vis Sci. 40: 2706-12. PMID: 10509669
    2. 通过基于结构的功能分析发现管状蛋白是转录因子。  |  Boggon, TJ., et al. 1999. Science. 286: 2119-25. PMID: 10591637
    3. 矮胖小鼠的耳蜗和视网膜退化  |  Ohlemiller, KK., et al. 1995. Neuroreport. 6: 845-9. PMID: 7612867
    4. 小鼠突变基因 tubby 的候选基因。  |  Noben-Trauth, K., et al. 1996. Nature. 380: 534-8. PMID: 8606774
    5. 新型管状基因家族成员 TUB, TULP1 和 TULP2 的分子特征及其与眼部疾病的可能关系。  |  North, MA., et al. 1997. Proc Natl Acad Sci U S A. 94: 3128-33. PMID: 9096357
    6. 视网膜色素变性患者中编码管状蛋白 TULP1 基因的隐性突变。  |  Hagstrom, SA., et al. 1998. Nat Genet. 18: 174-6. PMID: 9462750
    7. 两个患有常染色体隐性视网膜色素变性症的多米尼加家族成员的 TULP1 基因突变。  |  Banerjee, P., et al. 1998. Nat Genet. 18: 177-9. PMID: 9462751
    8. 常染色体隐性视网膜色素变性中的管状蛋白-1突变。  |  Gu, S., et al. 1998. Lancet. 351: 1103-4. PMID: 9660588
    9. 小鼠和人类中一种新型管状基因家族成员 TULP3 的分子特征。  |  Nishina, PM., et al. 1998. Genomics. 54: 215-20. PMID: 9828123

    订购信息

    产品名称产品编号规格价格数量收藏夹

    TULP3 抗体 (H-10)

    sc-393411
    200 µg/ml
    RMB2377.00

    TULP3 (H-10): m-IgG Fc BP-HRP 套装

    sc-530449
    200 µg Ab; 10 µg BP
    RMB2662.00

    TULP3 (H-10): m-IgGκ BP-HRP 套装

    sc-523936
    200 µg Ab, 40 µg BP
    RMB2662.00

    TULP3 抗体 (H-10) AC

    sc-393411 AC
    500 µg/ml, 25% agarose
    RMB3129.00

    TULP3 抗体 (H-10) HRP

    sc-393411 HRP
    200 µg/ml
    RMB2377.00

    TULP3 抗体 (H-10) FITC

    sc-393411 FITC
    200 µg/ml
    RMB2482.00

    TULP3 抗体 (H-10) PE

    sc-393411 PE
    200 µg/ml
    RMB2580.00

    TULP3 抗体 (H-10) Alexa Fluor® 488

    sc-393411 AF488
    200 µg/ml
    RMB2685.00

    TULP3 抗体 (H-10) Alexa Fluor® 546

    sc-393411 AF546
    200 µg/ml
    RMB2685.00

    TULP3 抗体 (H-10) Alexa Fluor® 594

    sc-393411 AF594
    200 µg/ml
    RMB2685.00

    TULP3 抗体 (H-10) Alexa Fluor® 647

    sc-393411 AF647
    200 µg/ml
    RMB2685.00

    TULP3 抗体 (H-10) Alexa Fluor® 680

    sc-393411 AF680
    200 µg/ml
    RMB2685.00

    TULP3 抗体 (H-10) Alexa Fluor® 790

    sc-393411 AF790
    200 µg/ml
    RMB2685.00

    Has anybody successfully used this to detect mouse Tulp3??? Having trouble getting results from another commercially available antibody. 

    Asked by: LabDot
    Thank you for your question. This antibody is recommended and warrantied for the detection of mouse Tulp3. Unfortunately we do not have data in mouse at this time.
    Answered by: Tech Service
    Date published: 2020-02-19

    I need to use an antibody to detect the protein in samples of bovine origin. Do you know if sc-393411: TULP3 (H-10) mouse monoclonal antibody will work?

    Asked by: AbPolly
    Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
    Answered by: Technical Support
    Date published: 2017-03-06
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    Rated 4 out of 5 by from Pleasantly suprisedWorks well. Size looks correct, get staining in the cilia. Have to use a good amount of laser power and gain on my microscope but it is clearly there. Do not get staining in the nucleus unless stimulated with a SHH pathway stimulant. For human fibroblasts fixed with PFA I recommend 1:1000, anything more concentrated results in terrible signal to noise. Have not tried less concentrated yet.
    Date published: 2018-05-21
    Rated 5 out of 5 by from Very good Western blot data of TULP3 expressionVery good Western blot data of TULP3 expression in ES-2 whole cell lysate. -SCBT QC
    Date published: 2014-02-16
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    TULP3 抗体 (H-10) is rated 4.5 out of 5 by 2.
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