Date published: 2025-9-6

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TRIM 抗体 (E-12): sc-393175

5.0(3)
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说明书
  • TRIM抗体(E-12)是小鼠单克隆IgG1 (lambda light chain),规格为200 µg/ml
  • 免疫原氨基酸序列11-197位于mouse物种的TRIM的内部区域内
  • 推荐用于 mouse, rat 和 human 来源的TRIM WB, IP, IF, IHC(P) 和 ELISA检测
  • m-IgGλ BP-HRP (mouse IgGλ binding protein-HRP)是 TRIM 抗体 (E-12) 在 WB and IHC(P) 应用中的首选二抗检测试剂。该试剂现与TRIM 抗体 (E-12) 组合成套装提供。 (请参阅下面的订购信息)。其他m-IgGλ BP 偶联产品,请参阅我们的 小鼠 IgG 结合蛋白完整列表。

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    関連項目

    TRIM(T细胞受体相互作用分子)是一种新型跨膜衔接蛋白,与人类T淋巴细胞和T细胞系中的TCR-CD3ζ复合物结合并共调节。TRIM是一种III型跨膜蛋白,包含一个8个氨基酸的胞外结构域和一个胞内结构域,胞内结构域包含4个潜在的磷酸化位点和8个酪氨酸残基,其中至少3个可能参与SH2介导的与其他信号蛋白的相互作用。人类TRIM基因位于染色体3q13,这是类风湿性关节炎的易感位点,靠近CD28、CD86和CD80基因,所有这些基因都编码T细胞共刺激分子。TRIM在T细胞和自然杀伤细胞中表达,但在B细胞或单核细胞中不表达。在T细胞中,TRIM定位于细胞膜并与CD3ζ和CD3ε结合。

    仅限研究使用。不适用于诊断和治疗用途。

    订购信息

    产品名称产品编号规格价格数量收藏夹

    TRIM 抗体 (E-12)

    sc-393175
    200 µg/ml
    RMB2377.00

    TRIM (E-12): m-IgGλ BP-HRP 套装

    sc-523838
    200 µg Ab, 40 µg BP
    RMB2662.00

    Can TRIM (E-12): sc-393175 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

    Asked by: cjMara
    Thank you for your question. Yes, TRIM (E-12): sc-393175 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Answered by: Technical Support
    Date published: 2017-02-27
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    Rated 5 out of 5 by from Good specificity in WB in CCRFGood specificity in WB in CCRF-CEM whole cell lysate. -SCBT QC
    Date published: 2015-06-01
    Rated 5 out of 5 by from Produced excellent immunoperoxidase membraneProduced excellent immunoperoxidase membrane and cytoplasmic staining in formalin fixed, paraffin-embedded human fetal thymus tissue. -SCBT QC
    Date published: 2015-04-12
    Rated 5 out of 5 by from Positive signal in WB in human transfectedPositive signal in WB in human transfected 293T whole cell lysates. -SCBT QC
    Date published: 2015-01-31
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    TRIM 抗体 (E-12) is rated 5.0 out of 5 by 3.
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