Date published: 2025-9-7
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TRB-2 Antibody (B-06) - Western Blotting - Image 34250
TRB-2 抗体 (B-06): sc-100878. Jurkat 全细胞裂解液中 TRB-2 表达的 Western 印迹分析.
TRB-2 Antibody (B-06) - Western Blotting - Image 34250
TRB-2 抗体 (B-06): sc-100878. Jurkat 全细胞裂解液中 TRB-2 表达的 Western 印迹分析.
TRB-2 Antibody (B-06) - Immunohistochemistry - Image 36200
TRB-2 抗体 (B-06): sc-100878. 对福尔马林固定, 石蜡包埋的人结肠组织进行免疫过氧化物酶染色, 显示细胞质定位.
TRB-2 Antibody (B-06) - Western Blotting - Image 153869
TRB-2 抗体 (B-06): sc-100878. 未转染: sc-117752 (A) 和小鼠 TRB-2 转染: sc-124270 (B) 293T 全细胞裂解液中 TRB-2 表达的 Western 印迹分析.
TRB-2 抗体 (B-06): sc-100878. Jurkat 全细胞裂解液中 TRB-2 表达的 Western 印迹分析.

TRB-2 抗体 (B-06): sc-100878

4.2(6)
寫評論提問

说明书
  • TRB-2抗体(B-06)是小鼠单克隆IgG2b λ, 在6篇文献中引用，规格为100 µg/ml
  • 免疫human物种的重组TRB-2
  • 推荐用于 mouse, rat 和 human 来源的TRB-2 WB, IP, IF, IHC(P) 和 ELISA检测
  • 目前，我们还没有完成TRB-2 抗体 (B-06)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

此外 TRB 抗体 包括 TRB-1, TRB-2和TRB-3

TRB-2（Tribbles同源物2），也称为TRIB2、C5FW或GS3955，是一种属于丝氨酸/苏氨酸蛋白激酶家族Tribbles亚家族的细胞质促凋亡蛋白。Tribbles亚家族的成员，即TRB-1、TRB-2和TRB-3，包含一个类似蛋白激酶或TRB结构域，但缺乏活性位点赖氨酸，因此似乎不显示激酶活性。TRB蛋白由有丝分裂原诱导，与MAPKKs相互作用并受其稳定。TRB蛋白在MAP激酶途径中发挥重要作用，这可以通过在TRB蛋白过度表达和表达不足时抑制MAPK信号来证明。TRB-1在骨髓、胰腺、骨骼肌、外周血白细胞和甲状腺中表达水平最高；TRB-2主要在外周血白细胞中表达；而TRB-3在胰腺、骨髓和外周血白细胞中表达水平最高。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

TRB-2 抗体 (B-06) 参考文献:

  1. 通过噬菌体展示鉴定作为自身免疫性葡萄膜炎自身抗原的tribbles homolog 2。  |  Zhang, Y., et al. 2005. Mol Immunol. 42: 1275-81. PMID: 15950723
  2. Trb2，一种小鼠的tribbles同源物，对于肾脏和小鼠发育是必需的。  |  Takasato, M., et al. 2008. Biochem Biophys Res Commun. 373: 648-52. PMID: 18593568
  3. 发作性睡病患者的tribbles同源物2特异性抗体水平升高。  |  Cvetkovic-Lopes, V., et al. 2010. J Clin Invest. 120: 713-9. PMID: 20160349
  4. Tribbles同源物2（Trib2）的转化需要Trib2激酶结构域和COP1的结合。  |  Keeshan, K., et al. 2010. Blood. 116: 4948-57. PMID: 20805362
  5. Tribbles 3：糖尿病主动脉重塑的潜在参与者。  |  Bailey, FP., et al. 2015. Biochem J. 467: 47-62. PMID: 25583260
  6. 小鼠tribbles同源物2的缺失会影响红系祖细胞发育，并导致小鼠大细胞性贫血。  |  Lin, KR., et al. 2016. Sci Rep. 6: 31444. PMID: 27550848
  7. Tribbles homolog 2通过磷酸酶1A介导的yes相关蛋白的稳定化促进肝纤维化和肝癌的发生。  |  Xiang, D., et al. 2021. Liver Int. 41: 1131-1147. PMID: 33386706
  8. Tribbles homolog 2 (Trib2)，一种在肿瘤发生和干细胞命运决定中起作用的假丝氨酸/苏氨酸激酶。  |  Fang, Y., et al. 2021. Cell Commun Signal. 19: 41. PMID: 33794905
  9. Tribbles homolog 2 在血管平滑肌细胞增殖中的作用。  |  Takaguri, A., et al. 2023. Cell Biol Int. 47: 787-795. PMID: 36626273
  10. Tribbles homolog 2在细胞增殖中的作用。  |  Zhang, W., et al. 2025. Cell Commun Signal. 23: 5. PMID: 39762856

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产品名称产品编号规格价格数量收藏夹

TRB-2 抗体 (B-06)

sc-100878
100 µg/ml
RMB2504.00

Dear, we got the card from Santacruz in our lab for the free monoclonal samples from Santa Cruz. It is written that we can contact you to get 10 mcl of trial size sample. I am very much interested in Trib2 antibody TRB-2 Antibody (B-06): sc-100878.

Asked by: Anna Kuchmiy
Thank you very much for your inquiry and for your interest in our products. sc-100878 is not provided as sample size. Note however that we offer a warranty of one year for the recommended applications and species after the purchase of the antibody. For additional information, please contact our technical service by email, phone or chat live.
Answered by: Technical Support Europe
Date published: 2017-10-04

I am using the LiCor/Odyssey system. Which secondary antibody do you recommend using with TRB-2 (B-06): sc-100878 monoclonal antibody?

Asked by: jenniferc
We recommend using one of our our exclusive Mouse IgG Binding Proteins (m-IgGλ) conjugated to CFL 680 or CFL 790. They are suitable for use with Near-Infrared (NIR) detection systems, such as LI-COR/Odyssey and other comparable systems. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Great monoclonal antibodyTRB-2 Antibody (B-06) is great for Western blot and IHC. It produced nice specific band with little to no background and robust immunostain
Date published: 2017-02-10
Rated 4 out of 5 by from Publishable data in ELISA using human bloodPublishable data in ELISA using human blood cells -SCBT Publication Review
Date published: 2015-07-20
Rated 4 out of 5 by from Bands detected in WB using Jurkat whole cellBands detected in WB using Jurkat whole cell lysate. -SCBT QC
Date published: 2015-07-07
Rated 4 out of 5 by from Worked well with transfected lysate by WBWorked well with transfected lysate by WB. -SCBT QC
Date published: 2015-06-04
Rated 4 out of 5 by from Publishable data in WB using normal humanPublishable data in WB using normal human lymphoblastic cell line, human acute myeloid leukaemia (AML) cell lines , AML patient sample and healthy human peripheral blood sample -SCBT Publication Review
Date published: 2015-02-25
Rated 4 out of 5 by from Robust immunoperoxidase cytoplasmic stainingRobust immunoperoxidase cytoplasmic staining in formalin-fixed, paraffin-embedded human colon tissue. -SCBT QC
Date published: 2015-01-27
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TRB-2 抗体 (B-06) is rated 4.2 out of 5 by 6.
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