Date published: 2025-9-6

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TNF-R1 抗体 (H398): sc-52739

4.3(7)
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说明书
  • TNF-R1 抗体 H398 是小鼠单克隆 IgG2a, 在8篇文献中引用,提供 100 µg/ml
  • 针对HL-60 human急性早幼粒细胞白血病细胞系
  • 推荐用于 human 来源的the extracellular and soluble TNF-R1 receptors WB, IP, IF 和 FCM检测
  • 看 TNF-R1 (H-5): sc-8436,可查看有标记的 TNF-R1 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前,我们还没有完成TNF-R1 抗体 (H398)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

肿瘤坏死因子(TNF)是一种多功能细胞因子,其功能通过两种不同的细胞表面受体来介导。这些受体分别被称为TNF-R1和TNF-R2,在大多数细胞类型上表达。TNF的大部分功能主要是通过TNF-R1介导的,而TNF-R2的信号传导则较少,仅限于免疫系统的细胞。这两种蛋白属于不断增长的TNF和神经生长因子(NGF)受体超家族,其中包括FAS、CD30、CD27和CD40。该超家族的成员是类型I膜蛋白,其序列同源性仅限于细胞外区域。TNF-R1与FAS以及三种结构不相关的信号蛋白TRADD、FADD和RIP)共享一种被称为"死亡结构域"的基序。这种"死亡结构域"是传导凋亡信号所必需的。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

TNF-R1 抗体 (H398)

sc-52739
100 µg/ml
RMB2377.00

Can TNF-R1 (H398): sc-52739 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: jerojero
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, TNF-R1 (H398): sc-52739 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Great features!This antibody works great in western blot analysis of TNF-R1 expression in Human cardiac fibroblasts cells.
Date published: 2022-11-01
Rated 5 out of 5 by from Excellent!This antibody works great in western blot analysis of TNF-R1 expression in 293T whole cell lysate.
Date published: 2017-02-06
Rated 4 out of 5 by from Publishable data in WB using human CD4+ cellsPublishable data in WB using human CD4+ cells. -SCBT Publication Review
Date published: 2015-05-17
Rated 4 out of 5 by from Band of interest seen in WB using 293T wholeBand of interest seen in WB using 293T whole cell lysate. -SCBT QC
Date published: 2015-05-08
Rated 4 out of 5 by from Publishable data in IF using human A549 cell linesPublishable data in IF using human A549 cell lines. -SCBT Publication Review
Date published: 2015-01-30
Rated 4 out of 5 by from Publishable data in CoIP using human A549Publishable data in CoIP using human A549 cell lines. -SCBT Publication Review
Date published: 2015-01-24
Rated 4 out of 5 by from Publishable data in IHC using human primaryPublishable data in IHC using human primary keratinocytes. -SCBT Publication Review
Date published: 2013-05-19
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TNF-R1抗体 (H398) is rated 4.3 out of 5 by 7.
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