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Thrombospondin 1 抗体 (3F357): sc-73158

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说明书
  • Thrombospondin 1抗体(3F357)是小鼠单克隆IgG1 κ, 在12篇文献中引用,规格为200 µg/ml
  • 针对human来源的还原和烷基化Thrombospondin 1
  • 推荐用于 mouse, rat, human, equine, bovine, porcine 和 canine 来源的reduced and non-reduced Thrombospondin 1 WB, IP, IF 和 IHC(P)检测
  • 另提供Alexa Fluor® 647, 偶联抗体,可用于IF、IHC(P)和FCM实验
  • 看 Thrombospondin 1 (C-8): sc-393504,可查看有标记的 Thrombospondin 1 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP是Thrombospondin 1 Antibody (3F357) 适用于 WB 和 IHC(P) 应用。 的首选辅助检测试剂。该试剂现与Thrombospondin 1 Antibody (3F357) 搭配使用(请参阅下面的订购信息)。
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血栓素原1抗体(3F357)是一种小鼠单克隆IgG1 kappa轻链抗体,用于检测人类血栓素原1(TSP-1),也称为THBS1,是一种参与细胞间和细胞与基质间通讯的重要糖蛋白。抗血栓素蛋白1抗体(3F357)针对还原和烷基化血栓素蛋白1上的表位,确保在蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和石蜡包埋切片免疫组织化学(IHCP)应用中表现出色。TSP-1通过与CD36、CD47、各种整合素、血管内皮生长因子(VEGF)和基质金属蛋白酶(MMP)等关键蛋白相互作用,在调节血管生成、血小板聚集、组织修复以及细胞粘附和迁移方面发挥着重要作用。血栓素原1单克隆抗体(3F357)具有广泛的物种反应性,能够有效识别小鼠、大鼠、人、马、牛、猪和犬样本中的还原和非还原形式的血栓素原1。抗血栓素原1抗体(3F357)能够详细研究血栓素原1在各种生物过程中的相互作用和功能,包括细胞外基质动态和细胞生长周期进展。TSP-1储存在血小板α颗粒中,并在激活时释放,有助于止血过程中的血小板聚集和粘附。血栓素原1(3F357)抗体是研究人员探索发育、伤口愈合和各种疾病病理的分子机制的重要工具。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Thrombospondin 1 抗体 (3F357) 参考文献:

  1. 血栓素蛋白-1的细胞生物学。  |  Chen, H., et al. 2000. Matrix Biol. 19: 597-614. PMID: 11102749
  2. 血栓素原-1在细胞凋亡中的作用。  |  Friedl, P., et al. 2002. Cell Mol Life Sci. 59: 1347-57. PMID: 12363037
  3. 血栓素原-1在心血管健康和病理中的作用。  |  Krishna, SM. and Golledge, J. 2013. Int J Cardiol. 168: 692-706. PMID: 23664438
  4. 血栓软蛋白-1在抗磷脂综合征发病机制中的作用。  |  Patsouras, M., et al. 2020. J Autoimmun. 115: 102527. PMID: 32709480
  5. 血栓素原-1通过调节血小板中的cAMP信号促进止血。  |  Aburima, A., et al. 2021. Blood. 137: 678-689. PMID: 33538796
  6. CD47和血栓素原-1对线粒体、代谢和糖尿病的调节。  |  Roberts, DD. and Isenberg, JS. 2021. Am J Physiol Cell Physiol. 321: C201-C213. PMID: 34106789
  7. 血栓素原-1介导Rho激酶抑制剂诱导的流出设施增加。  |  Shan, SW., et al. 2021. J Cell Physiol. 236: 8226-8238. PMID: 34180057
  8. 血栓素蛋白-1在实验性和人类支气管肺发育不良中起主要致病作用。  |  Ruschkowski, BA., et al. 2022. Am J Respir Crit Care Med. 205: 685-699. PMID: 35021035
  9. 内吞受体uPARAP是细胞外血栓素-1的调节因子。  |  Nørregaard, KS., et al. 2022. Matrix Biol. 111: 307-328. PMID: 35878760
  10. 通过联合阻断检查点和下调血栓素蛋白-1来改善癌症免疫疗法。  |  Xiao, Q., et al. 2023. Acta Pharm Sin B. 13: 3503-3517. PMID: 37655330

订购信息

产品名称产品编号规格价格数量收藏夹

Thrombospondin 1 抗体 (3F357)

sc-73158
200 µg/ml
$322.00

Thrombospondin 1 (3F357): m-IgG Fc BP-HRP 套装

sc-552883
200 µg Ab; 10 µg BP
$361.00

Thrombospondin 1 抗体 (3F357) Alexa Fluor® 647

sc-73158 AF647
200 µg/ml
$364.00

Are there any issues with using sc-73158: Thrombospondin 1 (3F357) mouse monoclonal primary antibody on mouse samples?

Asked by: Germaine
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent,we recommend using a directly conjugated primary antibody. Please contact our special orders department for pricing and availability of sc-73158 conjugates.
Answered by: Technical Support
Date published: 2017-03-07
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Rated 4 out of 5 by SH from Single strong band in CCDSingle strong band in CCD-1064Sk whole cell lysate. -SCBT QC
Date published: 2015-03-29
Rated 4 out of 5 by JT from Published IHC and WB data with mouse 4T1Published IHC and WB data with mouse 4T1 and breast cancer cell line - SCBT Publication Review
Date published: 2014-01-04
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Thrombospondin 1 抗体 (3F357) is rated 4.0 out of 5 by 2.
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