Thiazolyl Blue CAS: 298-93-1
MF: C18H16BrN5S
MW: 414.32

Thiazolyl Blue (CAS 298-93-1)

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Alternate Names: Thiazolyl Blue is also known at MTT, MMT Tetrazolium, and Thiazolyl Blue Tetrazolium Bromide
Application: Thiazolyl Blue may be used in measurement of cell proliferation and is a membrane-permeable dye reduced by mitochondrial enzymes
CAS Number: 298-93-1
Purity: ≥98%
Molecular Weight: 414.32
Molecular Formula: C18H16BrN5S
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).
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Thiazolyl Blue is a membrane-permeable yellow dye that is reduced by mitochondrial reductases in living cells to form the dark blue product, MTT Formazan (sc-215399). Spectrophotometric measurement of MTT Formazan at 540 or 570 nm allows quantitation of cell viability. Thiazolyl Blue is used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. Thiazolyl Blue is also an electron acceptor used for studying NADP-dependent dehydrogenases.

Physical State :
Solid
Solubility :
Soluble in water (20 mg/ml), ethanol (20 mg/ml), 2-methoxyethanol (20 mg/ml), buffered salt solutions (5 mg/ml), culture media (5 mg/ml), and PBS (5 mg/ml).
Storage :
Store at 4° C
Melting Point :
195° C (dec.)
仅供科研使用。不可用于诊断或治疗。
WGK Germany :
3
RTECS :
XF8060000
PubChem CID :
64965
MDL Number :
MFCD00011964
EC Number :
206-069-5
Beilstein Registry :
3825277
SMILES :
CC1=C(SC(=N1)[N+]2=NC(=NN2C3=CC=CC=C3)C4=CC=CC=C4)C.[Br-]

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Citations 1 to 10 of 13 total

PMID: # 30649537  Gorojod, RM.|Porte Alcon, S.|Dittler, ML.|Gonzalez, MC.|Kotler, ML.| et al. 2019. Toxicol. Sci. 169: 34-42.

PMID: # 27404580  2016. Eur J Pharm Sci. 92: 183-93.

PMID: # 26748999  Minaei, A. et al. 2016. Mol. Biol. Rep. 43: 99-105.

PMID: # 27137748  Aldahoun, MA. et al. 2016. Artif Cells Nanomed Biotechnol. 1-11.

PMID: # 26108872  Zahedifard, M. et al. 2015. Sci Rep. 5: 11544.

PMID: # 26214469  Wang, XW. et al. 2015. Genet. Mol. Res. 14: 7883-93.

PMID: # 25040994  Sabzichi, M. et al. 2014. Asian Pac. J. Cancer Prev. 15: 5311-6.

PMID: # 23294370  Xu, M. et al. 2013. Hepatol. Res. 43: 890-905.

PMID: # 24036512  Salim, LZ. et al. 2013. Molecules. 18: 11219-40.

PMID: # 22261727  Rani, MP. et al. 2012. J. Sci. Food Agric. 92: 1948-55.

Citations 1 to 10 of 13 total
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