Date published: 2025-9-7
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TGF beta Receptor 2/TGFBR2 Antibody (D-2) - Western Blotting - Image 376372
TGFβ RII 抗体 (D-2): sc-17799. A549 (A) 和 HUV-EC-C (B) 全细胞裂解液中 TGFβ RII 表达的 Western 印迹分析.
TGFβ RII 抗体 (D-2): sc-17799. A549 (A) 和 HUV-EC-C (B) 全细胞裂解液中 TGFβ RII 表达的 Western 印迹分析.

TGF beta Receptor 2/TGFBR2 抗体 (D-2): sc-17799

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寫評論提問

说明书
  • TGF beta Receptor 2/TGFBR2抗体(D-2)是小鼠单克隆IgG2b κ, 在42篇文献中引用，规格为200 µg/ml
  • 与氨基酸1-567结合，代表全长human起源的TFGβ RII
  • 抗-TGF beta Receptor 2/TGFBR2 抗体 (D-2) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA，检测mouse, rat 和human 来源的 TGFβ RII
  • 抗TGF beta Receptor 2/TGFBR2抗体（D-2）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取TGF beta Receptor 2/TGFBR2 (D-2): sc-17799的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP, m-IgG2b BP-HRP 和 m-IgGκ BP-HRP 是 TGF beta Receptor 2/TGFBR2 抗体 (D-2) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与TGF beta Receptor 2/TGFBR2 抗体 (D-2) 组合成套装提供。 (请参阅下面的订购信息)。

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描述
基因信息
说明书与实验方案
研究信息

関連項目

此外 TGF β Receptor 抗体 包括 TGF β RI, TGF β RII和TGF β RIII

TGFβ RII抗体（D-2）是一种小鼠单克隆IgG2b kappa轻链抗体，可识别人类、小鼠和大鼠的转化生长因子β受体II型（TGFβ RII），也称为TGFBR2。TGFβ RII 单克隆抗体（D-2）靶向全长人TGFβ RII蛋白，跨越1-567个氨基酸，适用于多种应用，包括蛋白质印迹（WB）、免疫沉淀（IP）、免疫荧光（IF）、免疫组织化学和酶联免疫吸附测定（ELISA）。TGFβ RII是一种单通道I型跨膜蛋白，在TGF-β信号传导通路中起着至关重要的作用，而该通路对于调节细胞生长、分化及凋亡等过程至关重要。TGFβ RII的结构完整性由其细胞外配体结合域和细胞内丝氨酸-苏氨酸激酶域决定，对于其在信号转导中的功能至关重要。与TGF-β配体结合后，TGFβ RII发生二聚化和磷酸化，促进I型受体的募集和激活，然后通过下游Smad蛋白传播信号，从而调节基因表达。这种结构机制对于维持细胞内环境平衡至关重要，对包括癌症、纤维化和免疫调节在内的各种生理和病理情况都有重要意义。抗TGFβ RII抗体（D-2）有结合和非结合两种形式，包括辣根过氧化物酶（HRP）、藻红蛋白（PE）、异硫氰酸荧光素（FITC）和Alexa Fluor®变体，可满足各种研究需求。TGFβ RII (D-2) 单克隆抗体支持对TGF-β信号传导通路及其在疾病机理中的作用的复杂性进行深入研究。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

订购信息

产品名称产品编号规格价格数量收藏夹

TGF beta Receptor 2/TGFBR2 抗体 (D-2)

sc-17799
200 µg/ml
RMB2377.00

TGF beta Receptor 2/TGFBR2 (D-2): m-IgG Fc BP-HRP 套装

sc-528318
200 µg Ab; 10 µg BP
RMB2662.00

TGF beta Receptor 2/TGFBR2 (D-2): m-IgGκ BP-HRP 套装

sc-520663
200 µg Ab, 40 µg BP
RMB2662.00

TGF beta Receptor 2/TGFBR2 (D-2): m-IgG2b BP-HRP 套装

sc-550027
200 µg Ab; 10 µg BP
RMB2662.00

TGF beta Receptor 2/TGFBR2 抗体 (D-2) AC

sc-17799 AC
500 µg/ml, 25% agarose
RMB3129.00

TGF beta Receptor 2/TGFBR2 抗体 (D-2) HRP

sc-17799 HRP
200 µg/ml
RMB2377.00

TGF beta Receptor 2/TGFBR2 抗体 (D-2) FITC

sc-17799 FITC
200 µg/ml
RMB2482.00

TGF beta Receptor 2/TGFBR2 抗体 (D-2) PE

sc-17799 PE
200 µg/ml
RMB2580.00

TGF beta Receptor 2/TGFBR2 抗体 (D-2) Alexa Fluor® 488

sc-17799 AF488
200 µg/ml
RMB2685.00

TGF beta Receptor 2/TGFBR2 抗体 (D-2) Alexa Fluor® 546

sc-17799 AF546
200 µg/ml
RMB2685.00

TGF beta Receptor 2/TGFBR2 抗体 (D-2) Alexa Fluor® 594

sc-17799 AF594
200 µg/ml
RMB2685.00

TGF beta Receptor 2/TGFBR2 抗体 (D-2) Alexa Fluor® 647

sc-17799 AF647
200 µg/ml
RMB2685.00

TGF beta Receptor 2/TGFBR2 抗体 (D-2) Alexa Fluor® 680

sc-17799 AF680
200 µg/ml
RMB2685.00

TGF beta Receptor 2/TGFBR2 抗体 (D-2) Alexa Fluor® 790

sc-17799 AF790
200 µg/ml
RMB2685.00

안녕하세요. 연세대학교 치과대학 구강병리학교실 입니다. TGFβ RII 항체 (D-2): sc-17799 와 TGFβ RII 항체 (E-6): sc-17792 의 무료 샘플을 신청하고 싶습니다. 절차 안내 부탁드립니다. 감사합니다.

Asked by: morbihan
Thank you for your question. It would be helpful if you could call us, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Support
Date published: 2021-07-22

Is this antibody good for Facs analysis on murine cells?

Asked by: Mara1234
The conjugated primary antibody is recommended and warrantied for flow cytometry (FCM). We do have previous citations with this antibody in flow cytometry on human cells, however we are still gathering data to show on our website. Check back for updates!
Answered by: Tech Service
Date published: 2020-01-07

What is the recommended secondary reagent to be used with this mouse monoclonal primary?

Asked by: jerojero
We recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support
Date published: 2017-01-27
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Rated 4 out of 5 by from Good antibody for WBWhile the antibody gives the expected band , there are one other non specific band in WB at much higher molecular weight. Does not work for surface staining by flow cytometry.
Date published: 2021-01-13
Rated 4 out of 5 by from Good Ab for WB analysisDilution 1:300 in 5% Milk/TBST, incubation OVN at 4°C, specific band
Date published: 2019-11-10
Rated 4 out of 5 by from Good antibody in WBWorks fine in WB (HCT116 cell lysate, dilution 1:300 in 5% Milk/TBST)
Date published: 2019-09-04
Rated 4 out of 5 by from TGFBRIIWe performed a western blot analysis of TGFBRII in 143B osteosarcoma cells. We could detected a good-signal intesity band.
Date published: 2017-06-23
Rated 5 out of 5 by from Specific antibodyThe (D-2) clone is specific for TGF beta RII, and is frequently cited in the literature for WB, IHC and FCM applications. This is just one of many popular clones offered by SCBT for this antigen.
Date published: 2016-12-19
Rated 5 out of 5 by from Publishable data for FCM in human bone marrowPublishable data for FCM in human bone marrow and spleen sections. -SCBT Publication Review
Date published: 2015-04-25
Rated 5 out of 5 by from Produced exceptional immunoperoxidase membraneProduced exceptional immunoperoxidase membrane and cytoplasmic staining in formalin-fixed, paraffin-embedded human lung tumor. -SCBT QC
Date published: 2015-04-24
Rated 5 out of 5 by from Publishable data in WB for the followingPublishable data in WB for the following human cell lines: HT29, SW480 and HCT116. -SCBT Publication Review
Date published: 2015-03-27
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TGF beta Receptor 2/TGFBR2 抗体 (D-2) is rated 4.6 out of 5 by 10.
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