Date published: 2025-9-8

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Teneurin-1 抗体 (B-1): sc-398018

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说明书
  • Teneurin-1 抗体 B-1 是小鼠单克隆 IgG2b (kappa轻链),Teneurin-1抗体,规格为200 µg/ml
  • 免疫原氨基酸序列26-135位于human物种的Teneurin-1的N-terminus附近
  • Teneurin-1 抗体 (B-1) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 Teneurin-1; 也和以下物种反应,包括: porcine
  • 抗Teneurin-1抗体(B-1)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取Teneurin-1 (B-1): sc-398018免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP, m-IgG2b BP-HRPm-IgGκ BP-HRP 是 Teneurin-1 抗体 (B-1) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与Teneurin-1 抗体 (B-1) 组合成套装提供。 (请参阅下面的订购信息)。

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    関連項目

    Teneurin-1抗体(B-1)是一种IgG2b κ小鼠单克隆Teneurin-1抗体(也称为Teneurin-1抗体),可通过WB, IP, IF, IHC(P) 和 ELISA检测小鼠、大鼠和人类来源的Teneurin-1蛋白。Teneurin-1抗体(B-1)既有非偶联形式的抗Teneurin-1抗体,也有多种偶联形式的抗Teneurin-1抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。Teneurin-1(Ten-1)也称为tenascin M1(TEN-M1)、TNM、ODZ1(odz,odd Oz/ten-m homolog 1)或ODZ3,是一种由2725个氨基酸组成的单次跨膜II型膜蛋白,属于tenascin家族和Teneurin亚家族。Teneurin-1定位于膜上并在胎儿大脑中表达,以二硫键连接的同源二聚体形式存在,被认为具有细胞信号转导功能。Teneurin-1含有富含脯氨酸的胞质区域,这些区域可能作为含有SH3的蛋白质的停靠结构域,以及八个类EGF结构域、二十三个YD重复序列、五个NHL重复序列和一个Teneurin N端结构域。编码Teneurin-1的基因位于人类X染色体q25区和小鼠X染色体A4区。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    Teneurin-1 抗体 (B-1) 参考文献:

    1. 绘制果蝇奇数 Oz(odz)的同源物:Doc4/Odz4 与小鼠的 7 号染色体,Odz1 与小鼠的 11 号染色体,以及 ODZ3 与人类的 Xq25 号染色体。  |  Ben-Zur, T. and Wides, R. 1999. Genomics. 58: 102-3. PMID: 10331952
    2. Teneurin-1是果蝇配对规则基因ten-m的脊椎动物同源物,是一种具有新型肝素结合结构域的神经元蛋白质。  |  Minet, AD., et al. 1999. J Cell Sci. 112 (Pt 12): 2019-32. PMID: 10341219
    3. 哺乳动物 Odz 基因家族:果蝇配对规则基因的同源物,其表达意味着不同但重叠的发育作用。  |  Ben-Zur, T., et al. 2000. Dev Biol. 217: 107-20. PMID: 10625539
    4. 小鼠的 Ten-m/Odz 基因在发育过程中和成年大脑中表现出不同但重叠的表达模式。  |  Zhou, XH., et al. 2003. Gene Expr Patterns. 3: 397-405. PMID: 12915301
    5. teneurin-1的胞内结构域与MBD1和CAP/ponsin相互作用,导致亚细胞共分布并转运至核基质。  |  Nunes, SM., et al. 2005. Exp Cell Res. 305: 122-32. PMID: 15777793
    6. Teneurin-1在发育中的大脑的相互连接区域表达,并在体内加工。  |  Kenzelmann, D., et al. 2008. BMC Dev Biol. 8: 30. PMID: 18366734
    7. 一名 10 岁女孩的先天获得性免疫缺陷综合征表现为肺心病。  |  Hays, MD., et al. 1991. Am Heart J. 121: 929-31. PMID: 2000766
    8. 人类天冬氨酸蛋白酶-1是转录因子EMX2在新型备选启动子上的直接靶标。  |  Beckmann, J., et al. 2011. BMC Dev Biol. 11: 35. PMID: 21651764
    9. Teneurin C-terminal associated peptides (TCAP):促肾上腺皮质激素释放因子 (CRF) 生理和行为的调节剂。  |  Chen, Y., et al. 2013. Front Neurosci. 7: 166. PMID: 24062636
    10. Teneurin C-末端相关肽(TCAP)-1和Latrophilin在HEK293细胞中的相互作用: 细胞间粘附调节的证据。  |  Husić, M., et al. 2019. Front Endocrinol (Lausanne). 10: 22. PMID: 30774623
    11. latrophilin-3的替代性剪接控制突触的形成。  |  Wang, S., et al. 2024. Nature. 626: 128-135. PMID: 38233523
    12. 突触伴侣匹配中Teneurin信号传导的分子和细胞机制。  |  Xu, C., et al. 2024. Cell. 187: 5081-5101.e19. PMID: 38996528

    订购信息

    产品名称产品编号规格价格数量收藏夹

    Teneurin-1 抗体 (B-1)

    sc-398018
    200 µg/ml
    $316.00

    Teneurin-1 (B-1): m-IgG Fc BP-HRP 套装

    sc-530662
    200 µg Ab; 10 µg BP
    $354.00

    Teneurin-1 (B-1): m-IgGκ BP-HRP 套装

    sc-524182
    200 µg Ab, 40 µg BP
    $354.00

    Teneurin-1 (B-1): m-IgG2b BP-HRP 套装

    sc-550210
    200 µg Ab; 10 µg BP
    $354.00

    Teneurin-1 抗体 (B-1) AC

    sc-398018 AC
    500 µg/ml, 25% agarose
    $416.00

    Teneurin-1 抗体 (B-1) HRP

    sc-398018 HRP
    200 µg/ml
    $316.00

    Teneurin-1 抗体 (B-1) FITC

    sc-398018 FITC
    200 µg/ml
    $330.00

    Teneurin-1 抗体 (B-1) PE

    sc-398018 PE
    200 µg/ml
    $343.00

    Teneurin-1 抗体 (B-1) Alexa Fluor® 488

    sc-398018 AF488
    200 µg/ml
    $357.00

    Teneurin-1 抗体 (B-1) Alexa Fluor® 546

    sc-398018 AF546
    200 µg/ml
    $357.00

    Teneurin-1 抗体 (B-1) Alexa Fluor® 594

    sc-398018 AF594
    200 µg/ml
    $357.00

    Teneurin-1 抗体 (B-1) Alexa Fluor® 647

    sc-398018 AF647
    200 µg/ml
    $357.00

    Teneurin-1 抗体 (B-1) Alexa Fluor® 680

    sc-398018 AF680
    200 µg/ml
    $357.00

    Teneurin-1 抗体 (B-1) Alexa Fluor® 790

    sc-398018 AF790
    200 µg/ml
    $357.00

    Can Teneurin-1 (B-1): sc-398018 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

    Asked by: AbPolly
    Thank you for your question. Yes, Teneurin-1 (B-1): sc-398018 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Answered by: Technical Support
    Date published: 2017-02-27
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    Rated 4 out of 5 by from detected high M.W. band in mouse brain extractThis Ab (200 fold-diluted) worked for WB in which mouse brain extract was separated.
    Date published: 2018-11-29
    Rated 4 out of 5 by from Primate retinaAntibody was tested under standard conditions (Long Y, Bordt AS, Liu WS, Davis EP, Lee SJ, Tseng L, Chuang AZ, Whitaker CM, Massey SC, Sherman MB, Marshak DW. Wide-field diffuse amacrine cells in the monkey retina contain immunoreactive Cocaine- and Amphetamine-Regulated Transcript (CART). Peptides. 2016 Oct;84:22-35). The isolated retina of a baboon was fixed for 60 minutes in 4% paraformaldehyde. Tissue was incubated for 9 days in a 1:1,000 solution of primary antibody with detergent and a blocking agent at 4 °C, washed, then incubated in an affinity-purified secondary antibody for 4 days at 4 °C, washed, and mounted in medium containing DAPI. No peptide blocking control was performed. Results: Light punctate labeling and low background throughout the optic fiber layer, ganglion cell layer, inner plexiform layer, and inner nuclear layer (less).
    Date published: 2017-06-01
    Rated 5 out of 5 by from Great immunofluorescence membrane stainingGreat immunofluorescence membrane staining in methanol-fixed HeLa cells. -SCBT QC
    Date published: 2015-04-30
    Rated 5 out of 5 by from Nice Western Blot data of TeneurinNice Western Blot data of Teneurin-1 expression in mouse brain tissue extract. -SCBT QC
    Date published: 2014-09-13
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    Teneurin-1 抗体 (B-1) is rated 4.5 out of 5 by 4.
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