Date published: 2025-9-7

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synphilin-1 抗体 (F-9): sc-365741

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说明书
  • synphilin-1 抗体 F-9 是小鼠单克隆 IgG1 κ,synphilin-1抗体, 在1篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列1-300位于human物种的synphilin-1的N-terminus
  • synphilin-1 抗体 (F-9) 推荐用于WB, IP, IF 和 ELISA,检测mouse, rat, human 来源的 synphilin-1
  • 抗synphilin-1抗体(F-9)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取synphilin-1 (F-9): sc-365741免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是synphilin-1 Antibody (F-9) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与synphilin-1 Antibody (F-9) 打包提供(请参阅下面的订购信息)。

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関連項目

synphilin-1抗体(F-9)是一种IgG1 κ小鼠单克隆synphilin-1抗体(也称为synphilin-1抗体),它通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和酶联免疫吸附测定(ELISA)等方法检测小鼠、大鼠和人类来源的synphilin-1蛋白。synphilin-1抗体(F-9)既以非共轭的抗synphilin-1抗体形式存在,也有多种共轭形式的抗synphilin-1抗体,包括琼脂糖、辣根过氧化物酶(HRP)、藻红蛋白(PE)、异硫氰酸荧光素(FITC)和多种Alexa Fluor®共轭物。Synphilin-1(α-突触核蛋白相互作用蛋白,SNCAIP)是一种由919个氨基酸组成的蛋白质,它与α-突触核蛋白相关,并促进神经元细胞中胞质内含物的形成。突触核蛋白家族成员,包括α-突触核蛋白和β-突触核蛋白,主要在大脑中表达,它们影响突触调节和神经元可塑性。Synphilin-1包含模块蛋白结构域,如锚蛋白样重复序列和卷曲螺旋结构域。虽然α-突触核蛋白和synphilin-1都在帕金森病(PD)患者的路易体中共同表达,但仅确定α-突触核蛋白基因的突变具有致病性。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

synphilin-1 抗体 (F-9) 参考文献:

  1. Synphilin-1 能与α-突触核蛋白结合,促进细胞膜包涵体的形成。  |  Engelender, S., et al. 1999. Nat Genet. 22: 110-4. PMID: 10319874
  2. 帕金森病的路易体中存在 Synphilin-1。  |  Wakabayashi, K., et al. 2000. Ann Neurol. 47: 521-3. PMID: 10762166
  3. 家族性帕金森病中 synphilin-1 的遗传分析。  |  Farrer, M., et al. 2001. Neurobiol Dis. 8: 317-23. PMID: 11300726
  4. α-突触核蛋白与 synphilin-1 的相互作用:帕金森病相关突变的影响。  |  Kawamata, H., et al. 2001. J Neurochem. 77: 929-34. PMID: 11331421
  5. 从人脑中鉴定出两种不同的突触核蛋白。  |  Jakes, R., et al. 1994. FEBS Lett. 345: 27-32. PMID: 8194594
  6. 分子克隆编码阿尔茨海默病淀粉样蛋白未识别成分的 cDNA。  |  Uéda, K., et al. 1993. Proc Natl Acad Sci U S A. 90: 11282-6. PMID: 8248242

订购信息

产品名称产品编号规格价格数量收藏夹

synphilin-1 抗体 (F-9)

sc-365741
200 µg/ml
RMB2377.00

synphilin-1 (F-9): m-IgG Fc BP-HRP 套装

sc-529452
200 µg Ab; 10 µg BP
RMB2662.00

synphilin-1 (F-9): m-IgGκ BP-HRP 套装

sc-522348
200 µg Ab, 40 µg BP
RMB2662.00

synphilin-1 (F-9): m-IgG1 BP-HRP 套装

sc-543523
200 µg Ab; 20 µg BP
RMB2662.00

synphilin-1 抗体 (F-9) AC

sc-365741 AC
500 µg/ml, 25% agarose
RMB3129.00

synphilin-1 抗体 (F-9) HRP

sc-365741 HRP
200 µg/ml
RMB2377.00

synphilin-1 抗体 (F-9) FITC

sc-365741 FITC
200 µg/ml
RMB2482.00

synphilin-1 抗体 (F-9) PE

sc-365741 PE
200 µg/ml
RMB2580.00

synphilin-1 抗体 (F-9) Alexa Fluor® 488

sc-365741 AF488
200 µg/ml
RMB2685.00

synphilin-1 抗体 (F-9) Alexa Fluor® 546

sc-365741 AF546
200 µg/ml
RMB2685.00

synphilin-1 抗体 (F-9) Alexa Fluor® 594

sc-365741 AF594
200 µg/ml
RMB2685.00

synphilin-1 抗体 (F-9) Alexa Fluor® 647

sc-365741 AF647
200 µg/ml
RMB2685.00

synphilin-1 抗体 (F-9) Alexa Fluor® 680

sc-365741 AF680
200 µg/ml
RMB2685.00

synphilin-1 抗体 (F-9) Alexa Fluor® 790

sc-365741 AF790
200 µg/ml
RMB2685.00

What is the position or sequence of the epitope in the sc-365741?

Asked by: seraph924
Thank you for your inquiry. sc-365741 is raised against amino acids 1-300 mapping at the N-terminus of synphilin-1 of human origin. Please contact our Technical Service Department if you have any other questions. Our Asian Technical Service team is available at (+86) 021-60936350 or [email protected] or by live chat on our website.
Answered by: Sen Li
Date published: 2023-11-20

What is the recommended fixation method for immunofluorescence staining with synphilin-1 (F-9): sc-365741 monoclonal antibody?

Asked by: Trav11
Thank you for your inquiry. We recommend fixing cells for 5 minutes in -10°C methanol and allowing to air dry. The full protocol can be viewed here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from It is good in hela cell WBLooks strong signal (1:1000) in hela whole cell lysis.
Date published: 2017-07-28
Rated 5 out of 5 by from Produced beautiful immunofluorescence cytoplasmicProduced beautiful immunofluorescence cytoplasmic staining in methanol-fixed HeLa cells. -SCBT QC
Date published: 2015-03-18
Rated 5 out of 5 by from Good Western Blot data of synphilinGood Western Blot data of synphilin-1 expression in U-87 MG whole cell lysate. -SCBT QC
Date published: 2013-06-13
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synphilin-1 抗体 (F-9) is rated 5.0 out of 5 by 3.
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