Date published: 2025-9-6

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SR-3A 抗体 (A-9): sc-390168

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说明书
  • SR-3A 抗体 A-9 是小鼠单克隆 IgG1 κ,SR-3A抗体, 在3篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列341-478位于human物种的SR-3A的C-terminus
  • SR-3A 抗体 (A-9) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 SR-3A
  • 抗SR-3A抗体(A-9)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取SR-3A (A-9): sc-390168免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是SR-3A Antibody (A-9) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与SR-3A Antibody (A-9) 打包提供(请参阅下面的订购信息)。

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関連項目

SR-3A抗体(A-9)是一种IgG1 κ小鼠单克隆SR-3A抗体(也称为HTR3A抗体、5HT3A抗体、5-羟色胺受体3A抗体、5-HT3A抗体、5-HT3R抗体、5-羟色胺门控离子通道受体抗体、5-羟色胺(5-HT)受体3A抗体、5HT3 5-羟色胺受体抗体或5-HT3-A抗体),该抗体通过蛋白质印迹、免疫沉淀、免疫荧光和酶联免疫吸附试验检测小鼠、大鼠和人的SR-3A蛋白。SR-3A抗体(A-9)既有非偶联的抗SR-3A抗体形式,也有多种偶联形式的抗SR-3A抗体,包括琼脂糖、辣根过氧化物酶、藻红蛋白、异硫氰酸荧光素和多种Alexa Fluor®偶联物。血清素(也被称为5-羟色胺或5-HT)是一种分子,它作为神经递质、激素和有丝分裂原发挥作用,并且主要在肠道、血小板和中枢神经系统(CNS)中表达。在中枢神经系统中,血清素调节多个过程,包括焦虑、睡眠、食欲、行为和药物滥用。在血小板和肠道中,血清素分别在心血管功能和胃肠道蠕动中发挥主要作用。血清素通过几种G蛋白偶联受体介导其作用,这些受体被称为5-HT受体或SR受体。SR-3是一种配体门控离子通道,而所有其他已知的血清素受体亚型都是G蛋白偶联受体。SR-4在中枢和外周神经系统中介导广泛的作用。SR-7属于G蛋白偶联受体的超家族。编码SR-7的基因定位于人类染色体10q21-q24。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

SR-3A 抗体 (A-9) 参考文献:

  1. 心脏发育需要羟色胺 2B 受体。  |  Nebigil, CG., et al. 2000. Proc Natl Acad Sci U S A. 97: 9508-13. PMID: 10944220
  2. 利用基因敲除小鼠剖析血清素系统在神经精神疾病中的作用。  |  Gingrich, JA. and Hen, R. 2001. Psychopharmacology (Berl). 155: 1-10. PMID: 11374326
  3. 药理受体的定义。  |  Kenakin, TP., et al. 1992. Pharmacol Rev. 44: 351-62. PMID: 1438521
  4. 血清素门控离子通道 5HT3 受体的初级结构和功能表达。  |  Maricq, AV., et al. 1991. Science. 254: 432-7. PMID: 1718042
  5. [皮质 5-羟色胺受体 3A(Htr3a)阳性抑制性神经元:类型和功能的多样性]  |  Wu, JY., et al. 2021. Sheng Li Xue Bao. 73: 295-305. PMID: 33903891
  6. 将 5HT7 受体基因 (HTR7) 分配到染色体 10q 并排除与妥瑞症的遗传联系。  |  Gelernter, J., et al. 1995. Genomics. 26: 207-9. PMID: 7601444
  7. 激活 cAMP 形成的高亲和性血清素受体(5-HT7)的分子克隆, 表征和定位。  |  Ruat, M., et al. 1993. Proc Natl Acad Sci U S A. 90: 8547-51. PMID: 8397408
  8. 将小鼠 Htr3 受体基因的人类同源物分配到染色体 11q23.1-q23.2 上。  |  Weiss, B., et al. 1995. Genomics. 29: 304-5. PMID: 8530095
  9. 中枢 5-HT4 受体  |  Eglen, RM., et al. 1995. Trends Pharmacol Sci. 16: 391-8. PMID: 8578609
  10. 通过原位杂交将5-羟色胺受体(HTR4)分配到人类5号染色体q31-->q33带。  |  Claeysen, S., et al. 1997. Cytogenet Cell Genet. 78: 133-4. PMID: 9371406
  11. 血清素通过 5-HT2A 受体诱导早期反应基因前列腺素 G/H 合成酶-2和egr-1的信号通路。  |  Goppelt-Struebe, M. and Stroebel, M. 1998. J Cell Physiol. 175: 341-7. PMID: 9572479
  12. 5-HT3B 亚基是决定血清素受体功能的主要因素。  |  Davies, PA., et al. 1999. Nature. 397: 359-63. PMID: 9950429

订购信息

产品名称产品编号规格价格数量收藏夹

SR-3A 抗体 (A-9)

sc-390168
200 µg/ml
RMB2377.00

SR-3A (A-9): m-IgGκ BP-HRP 套装

sc-523432
200 µg Ab, 40 µg BP
RMB2662.00

SR-3A (A-9): m-IgG1 BP-HRP 套装

sc-533581
200 µg Ab; 20 µg BP
RMB2662.00

SR-3A 抗体 (A-9) AC

sc-390168 AC
500 µg/ml, 25% agarose
RMB3129.00

SR-3A 抗体 (A-9) HRP

sc-390168 HRP
200 µg/ml
RMB2377.00

SR-3A 抗体 (A-9) FITC

sc-390168 FITC
200 µg/ml
RMB2482.00

SR-3A 抗体 (A-9) PE

sc-390168 PE
200 µg/ml
RMB2580.00

SR-3A 抗体 (A-9) Alexa Fluor® 488

sc-390168 AF488
200 µg/ml
RMB2685.00

SR-3A 抗体 (A-9) Alexa Fluor® 546

sc-390168 AF546
200 µg/ml
RMB2685.00

SR-3A 抗体 (A-9) Alexa Fluor® 594

sc-390168 AF594
200 µg/ml
RMB2685.00

SR-3A 抗体 (A-9) Alexa Fluor® 647

sc-390168 AF647
200 µg/ml
RMB2685.00

SR-3A 抗体 (A-9) Alexa Fluor® 680

sc-390168 AF680
200 µg/ml
RMB2685.00

SR-3A 抗体 (A-9) Alexa Fluor® 790

sc-390168 AF790
200 µg/ml
RMB2685.00

Hello--I saw from one reviewer that they had a good signal with this antibody in mouse cortex from a sample. Would it be possible for my lab to request a sample? Thank you.

Asked by: hwaxman
Please contact our technical service department on how to receive a free 10ug sample at 800-457-3801. Thank you.
Answered by: Technical Service
Date published: 2022-08-30

This anti body raised against amino acids 341-478 mapping at the C-terminus of SR-3A of human origin, Could you please tell me which you use which varient you use? 

Asked by: Yanning25
Thank you for your question. I am not sure what you are asking, but it was made against human SR-3A, accession#P46098.
Answered by: Tech Service
Date published: 2020-02-28

I have already used your SR-3A AB. Now I have urgent need to use a free sample copy from it to finish my study. Would you combine it with the recent FOT Bulgaria purchace. I have a coupon for my review that I have not still used. Pleaseq help me.

Asked by: Liliya
Thank you for your question. If you have an interest in testing a free 10 µg sample of sc-390168, please contact our Technical Service by phone or email or by Live Chat.
Answered by: SCBT Heidelberg Support
Date published: 2018-12-21

I need to use an antibody to detect the protein in samples of bovine origin. Do you know if sc-390168: SR-3A (A-9) mouse monoclonal antibody will work?

Asked by: DefinitelyNotMatt
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support
Date published: 2017-03-06
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Rated 4 out of 5 by from Works in mouse brain slicesI got a sample of this antibody and it worked just fine in mouse brain slices (cortex) 50 uM dilution 1:250. We got a strong signal.
Date published: 2020-09-01
Rated 5 out of 5 by from good antibodyThis antibody worked well in the western blotting using 1:1000
Date published: 2017-06-14
Rated 5 out of 5 by from Satisfactory Western blot data of SRSatisfactory Western blot data of SR-3A expression in non-transfected and human SR-3A transfected 293T whole cell lysates. -SCBT QC
Date published: 2013-01-08
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SR-3A 抗体 (A-9) is rated 4.7 out of 5 by 3.
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