Date published: 2025-9-7

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Sox-8 抗体 (H-7): sc-374446

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说明书
  • Sox-8 抗体 H-7 是小鼠单克隆 IgG1 κ,Sox-8抗体, 在4篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的Sox-8的内部区域内的氨基酸235-271之间
  • Sox-8 抗体 (H-7) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 Sox-8
  • 抗Sox-8抗体(H-7)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 可用于ChIP的TransCruz试剂(sc-374446 X, 200 µg/0.1 ml)
  • 关于如何获取Sox-8 (H-7): sc-374446免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是Sox-8 Antibody (H-7) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Sox-8 Antibody (H-7) 打包提供(请参阅下面的订购信息)。

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関連項目

Sox-8抗体(H-7)是一种IgG1κ小鼠单克隆Sox-8抗体(也称为SOX8抗体或SRY相关HMG-box转录因子8抗体),可通过WB、IP、IF和ELISA检测小鼠、大鼠和人源的Sox-8蛋白。Sox-8抗体(H-7)有非偶联抗Sox-8抗体形式和多种偶联形式的抗Sox-8抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。Sox基因包含与哺乳动物性别决定基因SRY相关的基因家族。这些基因类似地含有编码HMG-box结构域的序列,该结构域负责序列特异性DNA结合活性。Sox基因编码与发育过程中细胞命运决定和各种发育过程控制相关的推定转录调节因子。高度复杂的Sox基因簇集中在至少40个不同的位点,这些位点在各种动物谱系中迅速分化。目前,已鉴定出30个Sox基因。该家族的成员在进化过程中被证明是保守的,并在动物发育过程中发挥关键作用。一些与人类疾病有关,包括性反转。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Sox-8 抗体 (H-7) 参考文献:

  1. 鉴定新型 Sry 相关基因及其生殖细胞特异性表达。  |  Osaki, E., et al. 1999. Nucleic Acids Res. 27: 2503-10. PMID: 10359848
  2. Sox 因子在神经决定过程中的作用:进化中的保守信号传递?  |  Sasai, Y. 2001. Int J Dev Biol. 45: 321-6. PMID: 11291862
  3. HMG 盒超家族的起源和多样性。  |  Laudet, V., et al. 1993. Nucleic Acids Res. 21: 2493-501. PMID: 8506143
  4. 神经胶质细胞中的新型转录调节器 Sox10  |  Kuhlbrodt, K., et al. 1998. J Neurosci. 18: 237-50. PMID: 9412504
  5. 人类 SOX14 基因的特征和图谱。  |  Arsic, N., et al. 1998. Cytogenet Cell Genet. 83: 139-46. PMID: 9925951

订购信息

产品名称产品编号规格价格数量收藏夹

Sox-8 抗体 (H-7)

sc-374446
200 µg/ml
$316.00

Sox-8 (H-7): m-IgG Fc BP-HRP 套装

sc-529746
200 µg Ab; 10 µg BP
$354.00

Sox-8 (H-7): m-IgGκ BP-HRP 套装

sc-522741
200 µg Ab, 40 µg BP
$354.00

Sox-8 (H-7): m-IgG1 BP-HRP 套装

sc-543668
200 µg Ab; 20 µg BP
$354.00

Sox-8 抗体 (H-7) X

sc-374446 X
200 µg/0.1 ml
$316.00

Sox-8 抗体 (H-7) AC

sc-374446 AC
500 µg/ml, 25% agarose
$416.00

Sox-8 抗体 (H-7) HRP

sc-374446 HRP
200 µg/ml
$316.00

Sox-8 抗体 (H-7) FITC

sc-374446 FITC
200 µg/ml
$330.00

Sox-8 抗体 (H-7) PE

sc-374446 PE
200 µg/ml
$343.00

Sox-8 抗体 (H-7) Alexa Fluor® 488

sc-374446 AF488
200 µg/ml
$357.00

Sox-8 抗体 (H-7) Alexa Fluor® 546

sc-374446 AF546
200 µg/ml
$357.00

Sox-8 抗体 (H-7) Alexa Fluor® 594

sc-374446 AF594
200 µg/ml
$357.00

Sox-8 抗体 (H-7) Alexa Fluor® 647

sc-374446 AF647
200 µg/ml
$357.00

Sox-8 抗体 (H-7) Alexa Fluor® 680

sc-374446 AF680
200 µg/ml
$357.00

Sox-8 抗体 (H-7) Alexa Fluor® 790

sc-374446 AF790
200 µg/ml
$357.00

Sox-8 (H-7) 中和勝肽

sc-374446 P
100 µg/0.5 ml
$68.00

What application is the blocking peptide sc-374446 P appropriate for?

Asked by: cjMara
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-27
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Rated 5 out of 5 by from Good antibodyIF works well on frozen sections from 4% PFA fixed embryonic mouse brain.
Date published: 2022-12-06
Rated 5 out of 5 by from Works in Embryonic Neural Tissue for IHCWas able to get working well in embryonic PFA fixed neural tissue 1:150 O/N with Antigen Retrieval
Date published: 2017-08-17
Rated 3 out of 5 by from Not great for ChIPCompared Santa Cruz SOX8 antibody (sc-374446) directly to Abcam's SOX8 antibody (ab104245) via ChIP on sheared chromatin followed by qPCR. Santa Cruz SOX8 antibody gave a 2-fold qPCR enrichment over negative control, whereas 8-fold enrichment was seen with Abcam SOX8 antibody. So, while it works great for Western Blotting, it seems inferior for ChIP applications.
Date published: 2016-12-20
Rated 3 out of 5 by from Works well in WB with transfected lysatesWorks well in WB with transfected lysates -SCBT QC
Date published: 2014-10-29
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Sox-8 抗体 (H-7) is rated 4.0 out of 5 by 4.
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