Date published: 2025-9-8

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SENP3 抗体 (G-3): sc-133149

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说明书
  • SENP3抗体(G-3)是小鼠单克隆mouse IgG1 κ κ, 在3篇文献中引用,规格为200 µg/ml
  • 针对酸195-389,映射在SENP3的内部区域,human来源
  • 推荐用于 mouse, rat 和 human 来源的SENP3 WB, IP, IF 和 ELISA检测
  • 1 BP-HRP">m-IgG1 BP-HRP是SENP3 Antibody (G-3) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与SENP3 Antibody (G-3) 打包提供(请参阅下面的订购信息)。

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関連項目

SUMO(small ubiquitin-related modifier,小泛素相关修饰物)是泛素样蛋白家族的一员,可调节多种靶蛋白的多种细胞功能,包括转录、DNA修复、核质转运和染色体分离。SUMO前体蛋白在成熟过程中会被SUMO特异性蛋白酶在"GG"区域后的残基处进行切割。这种前体切割是随后进行SUMO化修饰的先决条件。sentrin特异性(或SUMO特异性)蛋白酶(SENP)蛋白属于肽酶C48家族,包括SENP1-3和SENP5-8。SENP1、SENP2和SENP3可降解UBL1和SMT3H2结合物,随后从SUMO化底物中释放单体。HIPK2是SENP1的一个去SUMO化目标,其在细胞质和细胞核之间穿梭。突变分析表明,SENP1在羧基末端区域含有核输出序列(NES),并且SENP1以NES依赖的方式输出到细胞质。SENP2已被证实为CTNNB1水平的下调因子,因此可能是Wnt通路的调节因子。SUMO蛋白酶SENP3可逆转MEF2的SUMO化,以增强其转录和成肌活性。SENP5定位于核仁,优先处理SUMO-3。它被认为在有丝分裂和/或细胞质分裂中发挥作用。SENP6定位于细胞质并释放SUMO-1。SENP6在生殖器官中的表达较高,表明其可能介导与生殖有关的过程。SENP8参与sentrins的释放。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

SENP3 抗体 (G-3)

sc-133149
200 µg/ml
$316.00

SENP3 (G-3): m-IgG1 BP-HRP 套装

sc-542640
200 µg Ab; 20 µg BP
$354.00

I am looking for an anti-SENP3 antibody suitable for flow cytometry. I will be using human samples

Asked by: issa
The conjugated primary antibody is recommended and warrantied for flow cytometry (FCM), however we are still gathering data to show on our website. Check back for updates!
Answered by: Technical Support
Date published: 2020-03-09

What is the recommended fixation method for immunofluorescence staining with SENP3 (G-3): sc-133149 monoclonal antibody?

Asked by: Cweed
Thank you for your inquiry. We recommend fixing cells for 5 minutes in -10°C methanol and allowing to air dry. The full protocol can be viewed here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
Answered by: Technical Support
Date published: 2017-02-24

I was wondering whether i could have a trial sample for the antibody SENP3 Antibody (G-3): sc-133149

Asked by: PARU
Thank you for your question. We do not currently offer a sample size for our mouse monoclonal, SENP3 Antibody (G-3): sc-133149. As an alternative, we do offer a sample size of a different clone to this same protein target, SENP3 Antibody (E-7): sc-137219. Please contact our Technical Service Department for more information and to request a sample. Please call our European Support office toll-free at 00800 4573 8000, email [email protected], or contact us by live chat.
Answered by: Technical Support
Date published: 2017-01-11
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Rated 5 out of 5 by from Strong and reliable for IF and WBSpecific and strong Western blot and immunofluorescence data on mouse and human samples. Great choice!
Date published: 2017-01-27
Rated 5 out of 5 by from Strong band in WB in human HeLa cellsStrong band in WB in human HeLa cells. -SCBT Publication Review
Date published: 2015-05-16
Rated 5 out of 5 by from Published for CoIP in human HeLa cellsPublished for CoIP in human HeLa cells. -SCBT Publication Review
Date published: 2015-04-11
Rated 5 out of 5 by from Produced great immunofluorescence nuclearProduced great immunofluorescence nuclear staining in formalin-fixed HepG2 cells. -SCBT QC
Date published: 2015-04-08
Rated 5 out of 5 by from Robust signal in WB in human transfectedRobust signal in WB in human transfected 293T whole cell lysates. -SCBT QC
Date published: 2015-03-26
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SENP3 抗体 (G-3) is rated 5.0 out of 5 by 5.
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