SB 224289 hydrochloride (CAS 180084-26-8 (free acid))

外观 :

Powder

物理状态 :

Solid

溶解度 :

Soluble in DMSO (10 mM, with gentle warming).

保存 :

Store at room temperature

沸点 :

724.8° C at 760 mmHg (Predicted)

折射率 :

n²⁰_D 1.69 (Predicted)

IC50 :

SR-1B: IC₅₀ = 2 nM (human); SR-1D: IC₅₀ = >1 µM (human); SR-1A: IC₅₀ = >1 µM (human); Serotonin transporter : IC₅₀ = 4.7 µM (human)

Ki 数据 :

SR-1B: K_i= 2.51 nM (human); SR-1D: K_i= 260 nM (human); SR-2C: K_i= 630.96 nM (human); D2DR: K_i= >1 µM (human); α-1a adrenergic receptor: K_i= >1 µM (rat)

PubChem CID :

MDL 号码 :

MFCD06407944

SMILES :

CC1=C(C=CC(=C1)C2=NOC(=N2)C)C3=CC=C(C=C3)C(=O)N4CCC5=C4C=C6C(=C5)OCC67CCN(CC7)C.Cl