Date published: 2026-10-24

1-800-457-3801

SCBT Portrait Logo
Seach Input
联系我们
登陆账户
快速订购
购物车 (0)
Rictor Antibody (H-11) - Immunofluorescence - Image 370933
Rictor 抗体 (H-11): sc-271081. 福尔马林固定的 HeLa 细胞免疫荧光染色, 显示细胞质小泡定位.
Rictor 抗体 (H-11): sc-271081. 福尔马林固定的 HeLa 细胞免疫荧光染色, 显示细胞质小泡定位.

Rictor 抗体 (H-11): sc-271081

4.6(18)
寫評論提問
说明书
  • Rictor 抗体 H-11 是小鼠单克隆 IgG2b κ，Rictor抗体, 在29篇文献中引用，规格为200 µg/ml
  • 免疫原氨基酸序列20-297位于human物种的Rictor的N-terminus附近
  • Rictor 抗体 (H-11) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA，检测mouse, rat 和human 来源的 Rictor; 也和以下物种反应，包括： canine
  • 抗Rictor抗体（H-11）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 2b BP-HRP">m-IgG2b BP-HRP是Rictor Antibody (H-11) 适用于 WB 和 IHC(P) 应用。 的首选辅助检测试剂。该试剂现与Rictor Antibody (H-11) 打包提供（请参阅下面的订购信息）。
Gene Editing Promo Banner

快捷链接

相关产品
描述
基因信息
蛋白序列
说明书与实验方案
研究信息

関連項目

Rictor抗体（H-11）是一种IgG2b κ小鼠单克隆Rictor抗体，可通过WB、IP、IF、IHC（P）和ELISA检测小鼠、大鼠和人类的Rictor蛋白。Rictor抗体（H-11）既可以是非偶联的抗Rictor抗体形式，也可以是多种偶联形式的抗Rictor抗体，包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。FRAP是一种大蛋白激酶，是雷帕霉素的哺乳动物靶点，雷帕霉素是一种免疫抑制剂，可阻止血管再狭窄，并具有潜在的抗癌作用。 FRAP的雷帕霉素不敏感伴侣，也称为Rictor，与D. discoidieum的pianissimo、S. pombe的STE20p和S. cerevisiae的AVO3p具有同源性。Rictor与FRAP形成复合物，这在细胞生长调控中很重要，因为它整合了生长因子和营养衍生信号。Rictor-FRAP复合物在PKCα磷酸化中发挥作用，直接在体外Ser473上磷酸化Akt/PKB，并通过PDK1促进Thr308磷酸化。它还可能作为已丧失PTEN表达的肿瘤的药物靶点，PTEN是一种反对Akt/PKB激活的肿瘤抑制因子。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Rictor 抗体 (H-11) 参考文献:

  1. 揭示Rictor在癌症中的影响：对mTORC2复合物的新见解。  |  Gkountakos, A., et al. 2018. Carcinogenesis. 39: 971-980. PMID: 29955840
  2. RICTOR扩增在靶向治疗和耐药性中的作用。  |  Zhao, D., et al. 2020. Mol Med. 26: 20. PMID: 32041519
  3. Rictor/mTORC2通过调节上皮重塑参与子宫内膜容受性。  |  Zhang, Y., et al. 2021. FASEB J. 35: e21731. PMID: 34131963
  4. mTOR-Rictor-EGFR轴在多形性胶质母细胞瘤的肿瘤发生和诊断中的作用。  |  Ramaiah, MJ. and Kumar, KR. 2021. Mol Biol Rep. 48: 4813-4835. PMID: 34132942
  5. Rictor是破骨细胞中TRAF6/TRAF3的新调节因子。  |  Xu, S., et al. 2021. J Bone Miner Res. 36: 2053-2064. PMID: 34155681
  6. HMGB1和RICTOR参与的RNA-RNA网络通过促进谷氨酰胺代谢促进肝细胞癌的肿瘤发生，并通过PD-L1+外泌体活性阻碍免疫治疗。  |  Wei, Y., et al. 2021. Signal Transduct Target Ther. 6: 421. PMID: 34916485
  7. Rictor 可在剪切应力作用下保持内皮的完整性。  |  Li, H., et al. 2022. Front Cell Dev Biol. 10: 963866. PMID: 36438564
  8. RICTOR潜在生物学功能和预后价值的全面泛癌分析。  |  Sun, Y., et al. 2023. Genes (Basel). 14: PMID: 37372460
  9. 新型RICTOR扩增携带实体：在下一代测序后，通过荧光原位杂交（FISH）验证肿瘤组织中的RICTOR扩增。  |  Sztankovics, D., et al. 2023. Sci Rep. 13: 19610. PMID: 37949943
  10. Rictor是一种mTORC2蛋白，通过AKT-FOXO1信号传导调节小鼠淋巴瓣的形成。  |  Banerjee, R., et al. 2024. Arterioscler Thromb Vasc Biol. 44: 2004-2023. PMID: 39087350

订购信息

产品名称产品编号规格价格数量收藏夹

Rictor 抗体 (H-11)

sc-271081
200 µg/ml
CNY2422.00

Rictor (H-11): m-IgG2b BP-HRP 套装

sc-548692
200 µg Ab; 10 µg BP
CNY2715.00

Rictor 抗体 (H-11) AC

sc-271081 AC
500 µg/ml, 25% agarose
CNY3189.00

Rictor 抗体 (H-11) HRP

sc-271081 HRP
200 µg/ml
CNY2422.00

Rictor 抗体 (H-11) FITC

sc-271081 FITC
200 µg/ml
CNY2527.00

Rictor 抗体 (H-11) PE

sc-271081 PE
200 µg/ml
CNY2625.00

Rictor 抗体 (H-11) Alexa Fluor® 488

sc-271081 AF488
200 µg/ml
CNY2738.00

Rictor 抗体 (H-11) Alexa Fluor® 546

sc-271081 AF546
200 µg/ml
CNY2738.00

Rictor 抗体 (H-11) Alexa Fluor® 594

sc-271081 AF594
200 µg/ml
CNY2738.00

Rictor 抗体 (H-11) Alexa Fluor® 647

sc-271081 AF647
200 µg/ml
CNY2738.00

Rictor 抗体 (H-11) Alexa Fluor® 680

sc-271081 AF680
200 µg/ml
CNY2738.00

Rictor 抗体 (H-11) Alexa Fluor® 790

sc-271081 AF790
200 µg/ml
CNY2738.00

What do you recommend for Antibody dilution? Nonfat Milk or BSA?

Asked by: Swoj
Thank you for your question. The recommended starting dilution for Western blotting is 1:200 (range 1:100-1:1,000). We recommend using 5% nonfat milk in TBST as blocking buffer, and antibody diluent. Please refer to our protocol online for further details.
Answered by: Technical Support
Date published: 2019-09-23

I am using the LiCor/Odyssey system. Which secondary antibody do you recommend using with Rictor (H-11): sc-271081?

Asked by: Trav11
We recommend using one of our our exclusive Mouse IgG Binding Proteins (m-IgGκ) conjugated to CFL 680 or CFL 790. They are suitable for use with Near-Infrared (NIR) detection systems, such as LI-COR/Odyssey and other comparable systems. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support 15
Date published: 2017-01-22
  • y_2026, m_10, d_24, h_5CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.48
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_zh_CN, sid_271081, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 100ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by Rosa from great antibodyI tested this antibody for western blot using three different cell lines, got a strong signal on as little as 10 ug of total protein.
Date published: 2021-10-15
Rated 5 out of 5 by gkyriakopoulos from Excellent antibodyExcellent antibody and excellent WB. In 3% milk / TBST
Date published: 2021-03-17
Rated 1 out of 5 by gaia12 from Anticorpo non performante.Abbiamo testato questo anticorpo su tonsilla umana e linfonodo reattivo alla condizione 1:50 ph6 e ph9.
Date published: 2021-03-09
Rated 4 out of 5 by mcostela from good!I tested both rictor antibodies (#271081 and #81538) on Western blot and they were quite specific
Date published: 2020-09-07
Rated 4 out of 5 by daniell from good for western1:1000 dilution in 3% BSA in PBST worked for western blotting of samples from mouse tissues and cells. Two bands were detected. It is likely the upper band is the right size.
Date published: 2017-11-29
Rated 5 out of 5 by caijingzeng from Good FeaturesI recommended for detection of Rictor of mouse, rat and human origin by WB
Date published: 2017-11-09
Rated 4 out of 5 by oasis mark from Its function is very good.I applied for this product sample sack and conducted western blot by using human kenay cancer cell, and found that it worked well.
Date published: 2017-07-11
Rated 5 out of 5 by abatista from Good stainingI used for staining mouse intestine tissue and it worked great (1:100)
Date published: 2017-06-12
  • y_2026, m_10, d_24, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.48
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_18
  • loc_zh_CN, sid_271081, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 7ms
  • REVIEWS, PRODUCT
Rictor 抗体 (H-11) is rated 4.6 out of 5 by 18.
  • y_2026, m_10, d_24, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.48
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_18
  • loc_zh_CN, sid_271081, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 93ms
  • REVIEWS, PRODUCT
1-800-457-3801
访问 Santa Cruz Animal Health|访问 San Juan Ranch
Santa Cruz Biotechnology, Inc. 是生物医学研究市场产品开发的世界领导者。请拨打1-800-457-3801联系我们。
版权所有© 2007-2026 Santa Cruz Biotechnology, Inc. 保留所有权利。”Santa Cruz Biotechnology” 和Santa Cruz Biotechnology, Inc.的商标，”Santa Cruz Animal Health”, “San Juan Ranch”, “Supplement of Champions”, San Juan Ranch的商标，”UltraCruz”, “ChemCruz”, “ImmunoCruz”, “ExactaCruz”, 和 “EZ Touch”是Santa Cruz Biotechnology, Inc.的注册商标。所有商标均为其各自所有者的财产。