Date published: 2025-9-8

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Ribosomal Protein LP0 抗体 (1B4): sc-293260

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说明书
  • Ribosomal Protein LP0 抗体 1B4 是小鼠单克隆 IgG2a κ,Ribosomal Protein LP0抗体, 在4篇文献中引用,规格为100 µg/ml
  • 免疫human物种的代表全长Ribosomal Protein LP0的氨基酸1-317
  • 推荐用于 mouse, rat 和 human 来源的Ribosomal Protein LP0 WB, IP, IF, IHC(P) 和 ELISA检测
  • 关于如何获取Ribosomal Protein LP0 (1B4): sc-293260免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP, m-IgG2a BP-HRPm-IgGκ BP-HRP 是 Ribosomal Protein LP0 抗体 (1B4) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与Ribosomal Protein LP0 抗体 (1B4) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

核糖体蛋白LP0抗体(1B4)是一种小鼠单克隆IgG2a kappa轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)、免疫组织化学和酶联免疫吸附测定(ELISA)检测小鼠、大鼠和人源的核糖体蛋白LP0。抗核糖体蛋白LP0抗体(1B4)有非结合形式。核糖体蛋白LP0,也称为RPLP0、P0、L10E或RPP0,是60S核糖体亚基的重要组成部分,由317个氨基酸组成,是一种中性磷蛋白。核糖体蛋白LP0在核糖体组装和翻译起始中发挥着至关重要的作用,它与核糖体蛋白LP1和LP2形成五聚体复合物,对于核糖体在蛋白质合成中的正常功能至关重要。核糖体蛋白LP0与其他核糖体蛋白的相互作用确保了核糖体的结构完整性和功能性,这对于细胞生长和增殖至关重要。值得注意的是,核糖体蛋白LP0的过度表达与肝癌和乳腺癌有关,这表明其在肿瘤发生中可能发挥的作用,并使核糖体蛋白LP0成为癌症研究中的关注目标。此外,与许多哺乳动物核糖体蛋白一样,核糖体蛋白LP0由多个经过处理的假基因代表,这些假基因分散在整个基因组中,这表明其进化意义和复杂性。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Ribosomal Protein LP0 抗体 (1B4) 参考文献:

  1. Trichosanthin 与酸性核糖体蛋白 P0 和 P1 以及有丝分裂检查点蛋白 MAD2B 相互作用。  |  Chan, SH., et al. 2001. Eur J Biochem. 268: 2107-12. PMID: 11277934
  2. 人类核糖体 '柄 '成分的亚细胞分布:P1, P2 和 P0 蛋白。  |  Tchórzewski, M., et al. 2003. Int J Biochem Cell Biol. 35: 203-11. PMID: 12479870
  3. L13a 从 60S 核糖体亚基的调节释放是转录本特异性翻译控制的一种机制。  |  Mazumder, B., et al. 2003. Cell. 115: 187-98. PMID: 14567916
  4. 真核翻译的分子力学。  |  Kapp, LD. and Lorsch, JR. 2004. Annu Rev Biochem. 73: 657-704. PMID: 15189156
  5. 通过杆状病毒介导表达并分离出携带功能状态 GST 标记的人类核糖体磷蛋白 P0。  |  Abo, Y., et al. 2004. Biochem Biophys Res Commun. 322: 814-9. PMID: 15336536
  6. 人类核糖体蛋白基因的特征和聚类。  |  Ishii, K., et al. 2006. BMC Genomics. 7: 37. PMID: 16504170
  7. 猪 RPLP0 基因全长 cDNA 的特征, 染色体定域和多态性。  |  Wu, X., et al. 2007. J Genet Genomics. 34: 104-8. PMID: 17469782
  8. 核糖体磷蛋白 P0 与 GCIP 相互作用,P0 的过表达与乳腺癌和肝癌细胞的增殖有关。  |  Chang, TW., et al. 2008. Oncogene. 27: 332-8. PMID: 17621266
  9. 核糖体蛋白RPLP0介导PLAAT4诱导的细胞周期阻滞和细胞凋亡。  |  Wang, CH., et al. 2019. Cell Biochem Biophys. 77: 253-260. PMID: 31131438
  10. 人类酸性核糖体磷酸蛋白 P0, P1 和 P2:cDNA 克隆, 体外合成和组装分析。  |  Rich, BE. and Steitz, JA. 1987. Mol Cell Biol. 7: 4065-74. PMID: 3323886
  11. 非小细胞肺癌中,miR-4731-5p通过靶向RPLP0增强凋亡并减轻上皮-间质转化。  |  Chang, C. and Xu, M. 2022. J Oncol. 2022: 3793318. PMID: 35342398
  12. 探索RPLP0、RPLP1和RPLP2在肺腺癌中的表达功能和预后价值。  |  Xu, C., et al. 2024. J Mol Histol. 55: 1079-1091. PMID: 39207634

订购信息

产品名称产品编号规格价格数量收藏夹

Ribosomal Protein LP0 抗体 (1B4)

sc-293260
100 µg/ml
RMB2377.00

Ribosomal Protein LP0 (1B4): m-IgG Fc BP-HRP 套装

sc-537731
100 µg Ab; 10 µg BP
RMB2662.00

Ribosomal Protein LP0 (1B4): m-IgGκ BP-HRP 套装

sc-535095
100 µg Ab; 40 µg BP
RMB2662.00

Ribosomal Protein LP0 (1B4): m-IgG2a BP-HRP 套装

sc-548096
100 µg Ab; 10 µg BP
RMB2662.00

I would like to ask about the epitope of RLP0 protein that is recognized by antibodies: sc-293260. I would be grateful for fast response.

Asked by: Barbara
Thank you for contacting Santa Cruz Biotechnology. The epitope range is 1-317. https://www.uniprot.org/uniprotkb/P05388/entry
Answered by: BlakeJ
Date published: 2024-06-27

Can sc-293260: Ribosomal Protein LP0 (1B4) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: AbPolly
Thank you for your question. Yes, sc-293260: Ribosomal Protein LP0 (1B4) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-03-24
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Rated 5 out of 5 by from Excellent!It works very well in WB and IF of SH-SY5Y cells and mouse primary neurons!
Date published: 2025-01-27
Rated 5 out of 5 by from Good for Western BlotAntibody works for Western blot with MKN-45 cell lysate in published research -SCBT QC
Date published: 2023-09-14
Rated 5 out of 5 by from excellent Ab for WBit works well in my experiment using 293T cell lysate
Date published: 2017-09-27
Rated 5 out of 5 by from an excellent antibody for WBThis antibody recognizes a strong band of predicted molecular weight (1:500 dilution, 30 ug HeLa total extract).
Date published: 2017-08-24
Rated 4 out of 5 by from Successful IHC staining of colon tissueBoth cancerous and normal colon tissue was successfully stained with this antibody by immunohistochemistry. There was minimal background.
Date published: 2017-03-30
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Ribosomal Protein LP0 抗体 (1B4) is rated 4.8 out of 5 by 5.
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