Date published: 2026-11-5

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RhoC 抗体 (37): sc-130339

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说明书
  • RhoC抗体(37)是小鼠单克隆IgG2a κ, 在1篇文献中引用,规格为200 µg/ml
  • 免疫human物种的重组Rho C
  • 推荐用于 human 来源的Rho C WB, IP 和 ELISA检测
  • 看 RhoC (C-10): sc-393090,可查看有标记的 RhoC 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP、 2a BP-HRP">m-IgG2a BP-HRP和m-IgGκ BP-HRP是RhoC Antibody (37) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与RhoC Antibody (37) 打包提供(请参阅下面的订购信息)。
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Ras p21鸟嘌呤核苷酸蛋白家族在信号转导通路中作用显著,在人类恶性肿瘤中突变频率高,使得该家族被广泛研究。然而,现在很清楚的是,Ras蛋白(H-、K-和N-Ras p21)是更大的相关蛋白超家族成员。该家族中六个成员,Rap 1A、Rap 1B、Rap 2、R-Ras、Ral A和Ral B,与Ras相比具有约50%的氨基酸同源性。六种哺乳动物Rho蛋白(Rho A、B、C、G、7和8)与Ras约有30%的同源性,并在多种细胞类型中表达。Ras p21和Rho p21以及Ras超家族其他成员都包含一个羧基末端CAAX序列(C,半胱氨酸;A,脂肪族氨基酸;X,任何氨基酸),在Ras中该序列对于正确定位和功能至关重要。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

含汞:所有HRP偶联物(包括组合装)均含有硫柳汞,这是一种汞化合物。请勿丢弃在垃圾中。应按照当地、州和联邦法规,将其作为危险化学品废弃物进行处置。

下载硫柳汞安全数据表(SDS)

RhoC 抗体 (37) 参考文献:

  1. 通过操纵组胺的产生,对工程化小鼠黑色素瘤进行表型分析,确定组胺H2受体和罗-C为组胺调节的黑色素瘤进展标志物。  |  Pós, Z., et al. 2005. Cancer Res. 65: 4458-66. PMID: 15899839
  2. 表皮生长因子通过激活Rho A和Rho C刺激人滋养层细胞迁移。  |  Han, J., et al. 2010. Endocrinology. 151: 1732-42. PMID: 20150581
  3. 火星草提取物通过调节 CCR5-CCL5 轴、Rho C 和磷酸化 FAK 抑制 A549 细胞迁移  |  Lin, SS., et al. 2016. Chin J Nat Med. 14: 203-9. PMID: 27025367
  4. 具有选择性位点紊乱的铁磁三元合金AB_{ρ}C_{1-ρ}的磁性行为:蜂窝晶格上混合自旋伊辛模型的案例研究。  |  Torrico, J., et al. 2020. Phys Rev E. 101: 032104. PMID: 32289902
  5. 从共存时的ρ(T)和T(ρ)关系估算临界常数Tc和ρc  |  Goodwin, RD. 1970. J Res Natl Bur Stand A Phys Chem. 74A: 221-227. PMID: 32523180
  6. 白血病相关Rho鸟嘌呤核苷酸交换因子和Ras同源家族成员C在胶质母细胞瘤细胞侵袭和抵抗中发挥作用  |  Ding, Z., et al. 2020. Am J Pathol. 190: 2165-2176. PMID: 32693062
  7. MicroRNA-20b-5p通过下调阿尔茨海默病Ras同源家族成员C加剧β-淀粉样蛋白诱导的神经细胞凋亡  |  Tian, Z., et al. 2021. Neurosci Lett. 742: 135542. PMID: 33278507
  8. 常染色体显性视网膜色素变性(RHO,c.68C>A (p.P23H)变异)的患病率估计和遗传多样性。  |  Leenders, M., et al. 2024. Am J Ophthalmol. 268: 340-347. PMID: 39278389
  9. 沉默Ras同源家族成员C对唾液腺腺样囊性癌的增殖、侵袭和迁移的影响。  |  Yu, W., et al. 2024. Hua Xi Kou Qiang Yi Xue Za Zhi. 42: 723-734. PMID: 39610069
  10. 人类ARH9 RAS相关基因重新定位至1p13-p21染色体。  |  Morris, SW., et al. 1993. Genomics. 15: 677-9. PMID: 8468062

订购信息

产品名称产品编号规格价格数量收藏夹

RhoC 抗体 (37)

sc-130339
200 µg/ml
CNY2422.00

RhoC (37): m-IgG Fc BP-HRP 套装

sc-537324
200 µg Ab; 10 µg BP
CNY2715.00

RhoC (37): m-IgGκ BP-HRP 套装

sc-534564
200 µg Ab; 40 µg BP
CNY2715.00

RhoC (37): m-IgG2a BP-HRP 套装

sc-547979
200 µg Ab; 10 µg BP
CNY2715.00

What is the recommended starting dilution for Western blot for Rho C (37): sc-130339 monoclonal antibody?

Asked by: Cweed
Thank you for your question. The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, can be found in the “datasheet” link at the top of the product page, for which I have provided the link: https://datasheets.scbt.com/sc-130339.pdf If you have any further questions or concerns, please contact our Technical Service department by calling 800-457-3801 option 2, emailing [email protected], or using the Live Chat function on our website.
Answered by: Technical Support
Date published: 2017-03-01
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Rated 3 out of 5 by StanK from very low titer, unspecific high MW bandsIn a very concentrated lysate (1.5 mg/ml total protein or above) the antibody does pick up decent ~20 kD band. But in more dilute samples there is no band or it very weak. Also, there are multiple non-specific bands, some are as bright as RhoC itself.
Date published: 2018-05-17
Rated 4 out of 5 by QZ from Strong band in WB in human recombinant RhoStrong band in WB in human recombinant Rho fusion protein. -SCBT QC
Date published: 2015-02-17
Rated 4 out of 5 by NZ from Good WB antibody in human HUVEC cell lineGood WB antibody in human HUVEC cell line. -SCBT Publication Review
Date published: 2013-12-01
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RhoC抗体 (37) is rated 3.7 out of 5 by 3.
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