Date published: 2025-9-7

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Rent1 抗体 (E-8): sc-166091

5.0(2)
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说明书
  • Rent1抗体(E-8)是小鼠单克隆IgG2b κ, 在2篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列71-370位于human物种的Rent1的N-terminus附近
  • 推荐用于 mouse, rat 和 human 来源的Rent1 WB, IP, IF, IHC(P) 和 ELISA检测
  • 可用于ChIP的TransCruz试剂(sc-166091 X, 200 µg/0.1 ml)
  • m-IgG Fc BP-HRP, m-IgG2b BP-HRPm-IgGκ BP-HRP 是 Rent1 抗体 (E-8) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与Rent1 抗体 (E-8) 组合成套装提供。 (请参阅下面的订购信息)。

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在真核生物中,检测和降解缺乏完整编码潜力的转录本的能力至关重要。无义介导的RNA降解(NMD)通过避免翻译具有显性负效应或有害功能获得潜力的截短肽来保护生物体。Rent1是Upflp的哺乳动物直系同源物,对胚胎存活至关重要。Rent1(也称为无义转录本和HUpf1的调节因子)包含一个N-末端锌指样结构域、NTPase结构域和一个由结构域组成的区域,这些结构域将Rent1定义为I类超家族解旋酶。Rent1蛋白具有核酸依赖的ATP酶活性和5'至3'解旋酶活性。此外,Rent1是一种RNA结合蛋白,其活性受ATP调节,并直接与Upf2p的哺乳动物同源物Rent2相互作用。Upf3p的两个哺乳动物直系同源物Rent3a和Rent3b由两个独立的基因编码。Rent3b(也称为Rent3X)由X连锁基因编码,主要定位于细胞核,而Rent 1和Rent 2主要定位于细胞质。Rent3蛋白与Y14和剪接mRNA的特异性相互作用表明Rent3a和Rent3b在细胞质中充当剪接和NMD之间的桥梁。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

Rent1 抗体 (E-8)

sc-166091
200 µg/ml
RMB2377.00

Rent1 (E-8): m-IgG Fc BP-HRP 套装

sc-537440
200 µg Ab; 10 µg BP
RMB2662.00

Rent1 (E-8): m-IgGκ BP-HRP 套装

sc-534708
200 µg Ab; 40 µg BP
RMB2662.00

Rent1 (E-8): m-IgG2b BP-HRP 套装

sc-549873
200 µg Ab; 10 µg BP
RMB2662.00

Rent1 抗体 (E-8) X

sc-166091 X
200 µg/0.1 ml
RMB2377.00

When should the TransCruz reagent sc-166091 X be used instead of the standard form sc-166091?

Asked by: jenniferc
Thank you for your question. We recommend using the TransCruz reagent form when performing ChIP or GelShift assays. This form can also be used in other applications such as Western Blot or IHC, but the dilution should be adjusted by a factor of 10 to account for the higher original concentration.
Answered by: Technical Support
Date published: 2017-02-25
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Rated 5 out of 5 by from Positive results in western blot analysisPositive results in western blot analysis of Rent1 expression in Sol8 whole cell lysate. -SCBT QC
Date published: 2015-05-23
Rated 5 out of 5 by from Produced superb immunoperoxidase cytoplasmicProduced superb immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human brain tissue. -SCBT QC
Date published: 2015-01-12
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Rent1 抗体 (E-8) is rated 5.0 out of 5 by 2.
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