Date published: 2025-9-6
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RARγ/Retinoic Acid Receptor γ Antibody (G-1) - Western Blotting - Image 1756
光稳定剂处理的 A-431 细胞核提取物中 RARγ 表达的 Western 印迹分析 (A, B). 测试的抗体包括 RARγ (C-19): sc-550 (A) 和 RARγ (G-1): sc-7387 (B).
RARγ/Retinoic Acid Receptor γ Antibody (G-1) - Western Blotting - Image 1756
光稳定剂处理的 A-431 细胞核提取物中 RARγ 表达的 Western 印迹分析 (A, B). 测试的抗体包括 RARγ (C-19): sc-550 (A) 和 RARγ (G-1): sc-7387 (B).
RARγ/Retinoic Acid Receptor γ Antibody (G-1) - Western Blotting - Image 48800
RARγ (G-1): sc-7387. 非转染: sc-117752 (A) 和小鼠 RARγ 转染: sc-122976 (B) 293T 全细胞裂解液中 RARγ 表达的 Western 印迹分析.
RARγ/Retinoic Acid Receptor γ Antibody (G-1) - Western Blotting - Image 379709
RARγ 抗体 (G-1): sc-7387. A-431 核提取物 (A) 和 F9 全细胞裂解液 (B) 中 RARγ 表达的 Western 印迹分析.
光稳定剂处理的 A-431 细胞核提取物中 RARγ 表达的 Western 印迹分析 (A, B). 测试的抗体包括 RARγ (C-19): sc-550 (A) 和 RARγ (G-1): sc-7387 (B).

RARγ/Retinoic Acid Receptor γ 抗体 (G-1): sc-7387

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寫評論提問

说明书
  • RARγ/Retinoic Acid Receptor γ抗体(G-1)是小鼠单克隆IgG2a κ, 在35篇文献中引用，规格为200 µg/ml
  • 免疫1-454氨基酸，对应于human来源RARγ全长
  • 抗-RARγ/Retinoic Acid Receptor γ 抗体 (G-1) 推荐用于 WB, IP 和 IF，检测mouse, rat 和human 来源的 RARγ1 and RARγ2
  • 抗RARγ/Retinoic Acid Receptor γ抗体（G-1）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 可用于凝胶迁移和ChIP的TransCruz试剂(sc-7387 X, 200 µg/0.1 ml)
  • 关于如何获取RARγ/Retinoic Acid Receptor γ (G-1): sc-7387的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP和 2a BP-HRP">m-IgG2a BP-HRP是RARγ/Retinoic Acid Receptor γ Antibody (G-1) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与RARγ/Retinoic Acid Receptor γ Antibody (G-1) 打包提供（请参阅下面的订购信息）。

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相关产品
描述
基因信息
蛋白序列
说明书与实验方案
研究信息

関連項目

额外RAR抗体，包括RAR α, RAR β, RAR β 2和RAR γ

RARγ抗体（G-1）是一种小鼠单克隆IgG2a kappa轻链抗体，可通过蛋白质印迹（WB）、免疫沉淀（IP）和免疫荧光（IF）检测小鼠、大鼠和人类样本中的RARγ。RARγ单克隆抗体（G-1）有非结合型和多种结合型，包括琼脂糖、辣根过氧化物酶、藻红蛋白、异硫氰酸荧光素和多种Alexa Fluor®结合物，可满足不同实验需求。RARγ是视黄酸受体家族的一员，在脊椎动物发育和组织分化过程中，它作为核转录因子在调节基因表达方面发挥着至关重要的作用。RARγ与维生素A的代谢产物视黄酸结合，这种结合对于功能至关重要，因为这种结合会诱导构象变化，从而促进受体与DNA的相互作用，进而促进靶基因的转录。RARγ以组织特异性方式表达，在皮肤和肺组织中发挥重要作用，在肺癌等病理条件下，其表达可能会发生变化。人类RARγ基因位于12q13染色体上，了解RARγ的功能和调节对于阐明健康和疾病中类维生素A信号传导的机制至关重要。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

RARγ/Retinoic Acid Receptor γ 抗体 (G-1) 参考文献:

  1. 视黄酸受体的分子生物学：孤儿从好家庭中寻找家园。  |  Rees, J. 1992. Br J Dermatol. 126: 97-104. PMID: 1311193
  2. 视黄酸受体（RAR）基因在人类, 小鼠和大鼠基因组中的染色体分配。  |  Mattei, MG., et al. 1991. Genomics. 10: 1061-9. PMID: 1655630
  3. 果蝇 EcR 基因编码一种蜕皮激素受体，它是类固醇受体超家族的一个新成员。  |  Koelle, MR., et al. 1991. Cell. 67: 59-77. PMID: 1913820
  4. 拮抗 RARγ 推动癌症干细胞的坏死。  |  Brown, G. 2022. Int J Mol Sci. 23: PMID: 35563205
  5. RARγ： 前列腺癌转移中内皮细胞的竞争之骨。  |  Bhowmick, S. and Bhowmick, NA. 2022. Cancer Res. 82: 2975-2976. PMID: 36052494
  6. RARγ通过激活JAK1-STAT3-CD24/MMPs轴促进甲状腺癌的侵袭和转移。  |  Zhang, FX., et al. 2023. Int Immunopharmacol. 125: 111129. PMID: 37897947
  7. 组蛋白乳酰化抑制巨噬细胞中的RARγ表达，通过激活TRAF6-IL-6-STAT3信号通路促进结直肠肿瘤的发生。  |  Li, XM., et al. 2024. Cell Rep. 43: 113688. PMID: 38245869
  8. 磷酸化增强了甲状腺激素受体与视黄醇 X 受体的靶基因序列依赖性二聚化。  |  Bhat, MK., et al. 1994. Proc Natl Acad Sci U S A. 91: 7927-31. PMID: 8058736
  9. 维甲酸在皮肤病学中的当前用途和未来潜在作用。  |  Orfanos, CE., et al. 1997. Drugs. 53: 358-88. PMID: 9074840
  10. [视黄酸对发育的基因控制]。  |  Mark, M., et al. 1997. C R Seances Soc Biol Fil. 191: 77-90. PMID: 9181129
  11. 维甲酸及其核受体在上消化道癌症的发展和预防中的作用。  |  Lotan, R. 1997. Environ Health Perspect. 105 Suppl 4: 985-8. PMID: 9255592
  12. 维甲酸和化学预防消化道癌症。  |  Lotan, R. 1997. Cancer Metastasis Rev. 16: 349-56. PMID: 9433644

订购信息

产品名称产品编号规格价格数量收藏夹

RARγ/Retinoic Acid Receptor γ 抗体 (G-1)

sc-7387
200 µg/ml
RMB2377.00

RARγ/Retinoic Acid Receptor γ (G-1): m-IgG Fc BP-HRP 套装

sc-525442
200 µg Ab; 10 µg BP
RMB2662.00

RARγ/Retinoic Acid Receptor γ (G-1): m-IgG2a BP-HRP 套装

sc-546257
200 µg Ab; 10 µg BP
RMB2662.00

RARγ/Retinoic Acid Receptor γ 抗体 (G-1) X

sc-7387 X
200 µg/0.1 ml
RMB2377.00

RARγ/Retinoic Acid Receptor γ 抗体 (G-1) AC

sc-7387 AC
500 µg/ml, 25% agarose
RMB3129.00

RARγ/Retinoic Acid Receptor γ 抗体 (G-1) HRP

sc-7387 HRP
200 µg/ml
RMB2377.00

RARγ/Retinoic Acid Receptor γ 抗体 (G-1) FITC

sc-7387 FITC
200 µg/ml
RMB2482.00

RARγ/Retinoic Acid Receptor γ 抗体 (G-1) PE

sc-7387 PE
200 µg/ml
RMB2580.00

RARγ/Retinoic Acid Receptor γ 抗体 (G-1) Alexa Fluor® 488

sc-7387 AF488
200 µg/ml
RMB2685.00

RARγ/Retinoic Acid Receptor γ 抗体 (G-1) Alexa Fluor® 546

sc-7387 AF546
200 µg/ml
RMB2685.00

RARγ/Retinoic Acid Receptor γ 抗体 (G-1) Alexa Fluor® 594

sc-7387 AF594
200 µg/ml
RMB2685.00

RARγ/Retinoic Acid Receptor γ 抗体 (G-1) Alexa Fluor® 647

sc-7387 AF647
200 µg/ml
RMB2685.00

RARγ/Retinoic Acid Receptor γ 抗体 (G-1) Alexa Fluor® 680

sc-7387 AF680
200 µg/ml
RMB2685.00

RARγ/Retinoic Acid Receptor γ 抗体 (G-1) Alexa Fluor® 790

sc-7387 AF790
200 µg/ml
RMB2685.00

Hello, why is written sc-7385X? What is the X meaning please? Thanks

Asked by: Valoury
Thank you for your question. X indicates the TransCruz reagent for Gel Supershift and ChIP applications (sc-7387 X, 200 µg/0.1 ml)
Answered by: Tech Support Europe
Date published: 2023-03-15

Can RARγ (G-1): sc-7387 be frozen?

Asked by: jenni
No. The antibody solution contains gelatin. When the gelatin is frozen the antibody precipitates out of solution. However, if an antibody’s datasheet says that the antibody should be stored frozen, then the antibody can be frozen, as these antibodies do not contain gelatin.
Answered by: Technical Support 7
Date published: 2017-01-25
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Rated 4 out of 5 by from Ab is specificResults provided in image. No Ab recognition detected in neg control RARy KO cell line.
Date published: 2017-11-02
Rated 5 out of 5 by from can buyWhat we can see is that retinoids are metabolites of vitamin A, which are important signaling molecules in the development and differentiation of vertebrates. Retinoic acid receptors and retinoid X receptors are nuclear transcription factors that modulate the effects of retinoids on gene expression. This is a very good product, you can buy long-term use.
Date published: 2017-02-03
Rated 5 out of 5 by from We got good results.Basebands were strong and clean, outstanding effect. Analysis of RAR expression in nuclear extracts treated with phorbol ester A-431 cells of Western blot (A, B) were good.
Date published: 2017-01-30
Rated 5 out of 5 by from Very popular choice!sc-7387 is a very popular mono for detection of RAR gamma in mouse, rat and human for a variety of applications including WB, IF and IHC(P). Featured in over 20 publications!
Date published: 2016-12-29
Rated 5 out of 5 by from Publishable data in EMSA using human HEK293T cellsPublishable data in EMSA using human HEK293T cells. -SCBT Publication Review
Date published: 2015-05-18
Rated 5 out of 5 by from Various publishable data in IHC(P) usingVarious publishable data in IHC(P) using human cholesteatomas and normal gastric epithelium, adenocarcinoma. -SCBT Publication Review
Date published: 2015-04-19
Rated 5 out of 5 by from Publishable data in WB using mouse F9Publishable data in WB using mouse F9, tumor, S91 and MCF-7 cells. -SCBT Publication Review
Date published: 2015-04-09
Rated 5 out of 5 by from Western BlotWestern Blot
Date published: 2015-04-06
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RARγ/Retinoic Acid Receptor γ 抗体 (G-1) is rated 4.9 out of 5 by 10.
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