Date published: 2025-9-6

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RANTES 抗体 (C-12): sc-373984

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说明书
  • RANTES抗体(C-12)是小鼠单克隆IgG3 κ, 在5篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的RANTES的C-terminus的氨基酸65-91之间
  • 推荐用于 mouse, rat 和 human 来源的RANTES WB, IP, IF 和 ELISA检测
  • m-IgG3 BP-HRP是RANTES Antibody (C-12) 适用于 WB 应用。 的首选辅助检测试剂,该试剂现与RANTES Antibody (C-12) 搭配使用(请参阅下面的订购信息)。

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在结构上,C-C或b-chemokines的特征是有一组保守的相邻半胱氨酸。该家族的成员包括MCP-1、MCP-2、MCP-3、MIP-1α、MIP-1β、RANTES和I-309。RANTES(激活后调节、正常T细胞表达和分泌)在血小板、嗜酸性粒细胞、成纤维细胞、巨噬细胞、内皮细胞和T淋巴细胞中表达。与chemokine家族一致,RANTES对单核细胞和NK细胞具有强的趋化活性。I-309最初被识别为γ/δ T淋巴细胞中的一种因子。I-309 cDNA编码一种长度为73个氨基酸的蛋白,具有一个潜在的N-连接糖基化位点。与C-C家族的其他成员不同,I-309不能诱导天然杀伤(NK)细胞的趋化。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

RANTES 抗体 (C-12) 参考文献:

  1. 培养的灵长类子宫内膜上皮细胞产生 RANTES。  |  Altman, GB., et al. 1999. Am J Reprod Immunol. 42: 168-74. PMID: 10517177
  2. 血小板沉积的 RANTES 会引发单核细胞停滞在发炎和动脉粥样硬化的内皮上。  |  von Hundelshausen, P., et al. 2001. Circulation. 103: 1772-7. PMID: 11282909
  3. 严重肺动脉高压中的趋化因子 RANTES。  |  Dorfmüller, P., et al. 2002. Am J Respir Crit Care Med. 165: 534-9. PMID: 11850348
  4. RANTES:多发性硬化症的遗传风险标记。  |  Gade-Andavolu, R., et al. 2004. Mult Scler. 10: 536-9. PMID: 15471370
  5. 哮喘患儿运动挑战后的呼出 RANTES 和白细胞介素 4 水平。  |  Keskin, O., et al. 2012. Ann Allergy Asthma Immunol. 109: 303-8. PMID: 23062383
  6. 候选直肠杀微生物剂 5P12-RANTES 在人体直肠洗液中的稳定性  |  Cerini, F., et al. 2017. AIDS Res Hum Retroviruses. 33: 768-777. PMID: 28177261
  7. 正常 T 细胞表达和分泌的活化调控(RANTES)推动了过敏性哮喘的缓解。  |  Li, N., et al. 2021. iScience. 24: 103163. PMID: 34693221
  8. 细胞介导的肾移植排斥反应中 RANTES 趋化因子的表达。  |  Pattison, J., et al. 1994. Lancet. 343: 209-11. PMID: 7507196
  9. RANTES 和 MCP-3 拮抗剂与多种趋化因子受体结合。  |  Gong, JH., et al. 1996. J Biol Chem. 271: 10521-7. PMID: 8631850
  10. 经过 CD26 处理的 RANTES(3-68)具有强大的抗 HIV-1 活性,而完整的 RANTES 则没有这种活性。  |  Schols, D., et al. 1998. Antiviral Res. 39: 175-87. PMID: 9833958

订购信息

产品名称产品编号规格价格数量收藏夹

RANTES 抗体 (C-12)

sc-373984
200 µg/ml
RMB2377.00

RANTES (C-12): m-IgG3 BP-HRP 套装

sc-550444
200 µg Ab; 40 µg BP
RMB2662.00

RANTES (C-12) 中和勝肽

sc-373984 P
100 µg/0.5 ml
RMB511.00

What application is the blocking peptide sc-373984 P appropriate for?

Asked by: AbPolly
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Nice western blot detection of RANTESWe used this antibody for expression detection of RANTES by western blot. We got a nice band around the correct molecular weight in human tissue.
Date published: 2017-02-07
Rated 5 out of 5 by from Good Western Blot data of RANTES expressionGood Western Blot data of RANTES expression in human platelet extract. -SCBT QC
Date published: 2015-03-30
Rated 5 out of 5 by from Nice Western Blot data of human recombinantNice Western Blot data of human recombinant RANTES fusion protein. -SCBT QC
Date published: 2013-10-19
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RANTES 抗体 (C-12) is rated 5.0 out of 5 by 3.
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