Date published: 2026-10-24

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PSD-95 Antibody (6G6) - Western Blotting - Image 373403
PSD-95 抗体 (6G6): sc-32291. 小鼠大脑 (A) 和大鼠大脑 (B) 组织提取物中 PSD-95 表达的 Western 印迹分析.
PSD-95 抗体 (6G6): sc-32291. 小鼠大脑 (A) 和大鼠大脑 (B) 组织提取物中 PSD-95 表达的 Western 印迹分析.

PSD-95 抗体 (6G6): sc-32291

4.6(5)
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说明书
  • PSD-95抗体(6G6)是小鼠单克隆IgG2a κ, 在11篇文献中引用，规格为200 µg/ml
  • 针对rat来源的纯化重组PSD-95
  • 推荐用于 mouse, rat 和 human 来源的PSD-95 WB, IP 和 IF检测
  • 看 PSD-95 (7E3): sc-32290，可查看有标记的 PSD-95 抗体，包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP和m-IgGκ BP-HRP是PSD-95 Antibody (6G6) 适用于 WB 应用。 的首选辅助检测试剂，这些试剂现与PSD-95 Antibody (6G6) 打包提供（请参阅下面的订购信息）。
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额外Post-Synaptic Density Protein抗体，包括PSD-95

果蝇discs large (dlg)肿瘤抑制基因最初是通过对果蝇胚胎遗传学分析而被发现的。随后又发现了几种哺乳动物同源基因，并将它们归类为MAGUK（膜相关环磷酸腺苷激酶同源基因）蛋白家族。人类的dlg同源基因包括hdlg-1（大鼠SAP 97）和NE-dlg（神经元和内分泌dlg）。大鼠突触蛋白PSD-95（也称为SAP 90）也与这些蛋白有同源性。MAGUKs定位于膜-细胞骨架界面，具有几个不同的结构域，表明这些蛋白可能在细胞内信号转导中发挥作用。hdlg-1和NE-dlg与肿瘤抑制蛋白APC的相互作用表明，MAGUK蛋白也可能在调节生长中发挥作用。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

PSD-95 抗体 (6G6) 参考文献:

  1. PSD-95样膜相关鸟苷酸激酶（PSD-MAGUK）和突触可塑性。  |  Xu, W. 2011. Curr Opin Neurobiol. 21: 306-12. PMID: 21450454
  2. Ephrin-B3将PSD-95招募到突触。  |  Fei, E., et al. 2015. Nat Neurosci. 18: 1535-7. PMID: 26505562
  3. 翻译后修饰调节PSD-95的突触定位。  |  Vallejo, D., et al. 2017. Mol Neurobiol. 54: 1759-1776. PMID: 26884267
  4. 突触后密度蛋白95（PSD-95）由KIF5转运到树突区域。  |  Yoo, KS., et al. 2019. Mol Brain. 12: 97. PMID: 31753031
  5. NMDA-LTD的诱导不需要PSD-95的丝氨酸73位磷酸化。  |  Nowacka, A., et al. 2020. Sci Rep. 10: 2054. PMID: 32029829
  6. 与PSD-95及其相互作用伴侣相关的神经发育障碍。  |  Levy, AM., et al. 2022. Int J Mol Sci. 23: PMID: 35457207
  7. dCA1中PSD-95的丝氨酸73位磷酸化是情境恐惧消退所必需的。  |  Ziółkowska, M., et al. 2023. PLoS Biol. 21: e3002106. PMID: 37155709
  8. 多价Tau/PSD-95相互作用可阻止模拟突触后密度的体外凝结和聚集。  |  Shen, Z., et al. 2023. Nat Commun. 14: 6839. PMID: 37891164
  9. 靶向突触后支架蛋白PSD-95可增强BDNF信号传导，从而减轻小鼠的抑郁样行为。  |  Shi, X., et al. 2024. Sci Signal. 17: eadn4556. PMID: 38687826
  10. 靶向TrkB-PSD-95耦联以减轻神经系统疾病。  |  Yang, X., et al. 2025. Neural Regen Res. 20: 715-724. PMID: 38886937

订购信息

产品名称产品编号规格价格数量收藏夹

PSD-95 抗体 (6G6)

sc-32291
200 µg/ml
CNY2422.00

PSD-95 (6G6): m-IgG Fc BP-HRP 套装

sc-536733
200 µg Ab; 10 µg BP
CNY2715.00

PSD-95 (6G6): m-IgGκ BP-HRP 套装

sc-533894
200 µg Ab; 40 µg BP
CNY2715.00

What is the recommended starting dilution for Western blot for sc-32291: PSD-95 (6G6) monoclonal antibody?

Asked by: Professor Griffin
The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, is available in the recommended protocol: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
Answered by: Technical Support
Date published: 2017-03-22
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Rated 5 out of 5 by z_daliang from strong signalThe use of this antibody WB in 1:1000 shows strong signal and clear bands. This antibody played an important role in my experiment.
Date published: 2017-06-03
Rated 5 out of 5 by Mingge from Great Western Blot dataGreat Western Blot data of PSD-95 expression in HeLa whole cell lysates,recommend Hela cell for positive control.
Date published: 2017-02-12
Rated 5 out of 5 by Jinghuan from good resultOur laboratory has focused on the protein expression, we used this antibody to detect mouse kidney tissue, diluted 1:500, and obtained a specific strong band.
Date published: 2017-01-17
Rated 4 out of 5 by HF from Positive result in WB in mouse brain tissuePositive result in WB in mouse brain tissue extract. -SCBT QC
Date published: 2015-05-17
Rated 4 out of 5 by LM from IHC publishable data with rat hippocampal neuronsIHC publishable data with rat hippocampal neurons - SCBT Publication Review
Date published: 2014-02-27
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PSD-95 抗体 (6G6) is rated 4.6 out of 5 by 5.
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