Date published: 2025-9-6

021-6093-6350

SCBT Portrait Logo
Seach Input

Protein C 抗体 (C-10): sc-377175

3.7(3)
寫評論提問

说明书
  • Protein C 抗体 C-10 是小鼠单克隆 IgG1 (kappa轻链),Protein C抗体,规格为200 µg/ml
  • 免疫原氨基酸序列256-395位于human物种的Protein C的C-terminus附近
  • Protein C 抗体 (C-10) 推荐用于WB, IP, IF 和 ELISA,检测mouse, rat, human 来源的 Protein C
  • 抗Protein C抗体(C-10)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取Protein C (C-10): sc-377175免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是Protein C Antibody (C-10) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Protein C Antibody (C-10) 打包提供(请参阅下面的订购信息)。

    快捷链接

    関連項目

    蛋白质C抗体(C-10)是一种IgG1κ小鼠单克隆蛋白质C抗体(也称为蛋白质C抗体),通过WB、IP、IF和ELISA检测小鼠、大鼠和人类来源的蛋白质C。蛋白质C抗体(C-10)既有非偶联的抗蛋白质C抗体形式,也有多种偶联形式的抗蛋白质C抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。蛋白质C是一种维生素K依赖性血浆蛋白,在肝脏中产生,由两条多肽链组成。它是一种重要的抗凝剂,由与内皮表面受体结合的凝血酶激活,并通过酶促裂解因子V和VIII的活化形式,从而抑制血液凝固。蛋白质C在初级结构上与凝血因子原组相似。人血浆中蛋白质C的正常浓度约为1-3ng/ml,前酶浓度约为3µg/ml。蛋白质C缺乏与遗传性血栓形成倾向有关,这是一种罕见的遗传性疾病,易使受影响的人患静脉血栓和习惯性流产。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    Protein C 抗体 (C-10) 参考文献:

    1. 炎症和活化蛋白 C 抗凝途径。  |  Esmon, CT. 2006. Semin Thromb Hemost. 32 Suppl 1: 49-60. PMID: 16673266
    2. 重组人活化蛋白 C 能上调人内皮细胞中可溶性碎裂碱的释放。  |  Brueckmann, M., et al. 2006. Br J Haematol. 133: 550-7. PMID: 16681644
    3. 蛋白 C 基因第 6 外显子的新型同源突变导致严重的 I 型蛋白 C 缺乏症和新生儿紫癜。  |  Abu-Amero, KK., et al. 2006. J Thromb Haemost. 4: 1152-3. PMID: 16689776
    4. 蛋白 C 和血栓调节蛋白在调节血液凝固中的作用。  |  Esmon, CT. 1989. J Biol Chem. 264: 4743-6. PMID: 2538457
    5. 遗传性血栓性疾病:活化蛋白 C 抗性是静脉血栓栓塞症的致病因素。  |  Dahlbäck, B. 1995. Blood. 85: 607-14. PMID: 7833465
    6. 与活化蛋白 C 抗性有关的血液凝固因子 V 变异。  |  Bertina, RM., et al. 1994. Nature. 369: 64-7. PMID: 8164741
    7. 家族性血栓性血友病是由于一种以前未被发现的机制造成的,其特点是对活化蛋白 C 的抗凝反应不佳:预测活化蛋白 C 的辅助因子。  |  Dahlbäck, B., et al. 1993. Proc Natl Acad Sci U S A. 90: 1004-8. PMID: 8430067
    8. 患有遗传性血栓性疾病的妇女胎儿丢失率增加。  |  Preston, FE., et al. 1996. Lancet. 348: 913-6. PMID: 8843809
    9. 先天性血栓性疾病中的蛋白 C 缺乏症。  |  Griffin, JH., et al. 1981. J Clin Invest. 68: 1370-3. PMID: 6895379

    订购信息

    产品名称产品编号规格价格数量收藏夹

    Protein C 抗体 (C-10)

    sc-377175
    200 µg/ml
    RMB2377.00

    Protein C (C-10): m-IgGκ BP-HRP 套装

    sc-523224
    200 µg Ab, 40 µg BP
    RMB2662.00

    Protein C (C-10): m-IgG1 BP-HRP 套装

    sc-533564
    200 µg Ab; 20 µg BP
    RMB2662.00

    Protein C 抗体 (C-10) AC

    sc-377175 AC
    500 µg/ml, 25% agarose
    RMB3129.00

    Protein C 抗体 (C-10) HRP

    sc-377175 HRP
    200 µg/ml
    RMB2377.00

    Protein C 抗体 (C-10) FITC

    sc-377175 FITC
    200 µg/ml
    RMB2482.00

    Protein C 抗体 (C-10) PE

    sc-377175 PE
    200 µg/ml
    RMB2580.00

    Protein C 抗体 (C-10) Alexa Fluor® 488

    sc-377175 AF488
    200 µg/ml
    RMB2685.00

    Protein C 抗体 (C-10) Alexa Fluor® 546

    sc-377175 AF546
    200 µg/ml
    RMB2685.00

    Protein C 抗体 (C-10) Alexa Fluor® 594

    sc-377175 AF594
    200 µg/ml
    RMB2685.00

    Protein C 抗体 (C-10) Alexa Fluor® 647

    sc-377175 AF647
    200 µg/ml
    RMB2685.00

    Protein C 抗体 (C-10) Alexa Fluor® 680

    sc-377175 AF680
    200 µg/ml
    RMB2685.00

    Protein C 抗体 (C-10) Alexa Fluor® 790

    sc-377175 AF790
    200 µg/ml
    RMB2685.00

    What is the recommended fixation method for immunofluorescence staining with Protein C (C-10): sc-377175 monoclonal antibody?

    Asked by: Dr Ninau Qelp
    Thank you for your inquiry. We recommend fixing cells for 5 minutes in -10°C methanol and allowing to air dry. The full protocol can be viewed here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
    Answered by: Technical Support
    Date published: 2017-02-24
    • y_2025, m_9, d_6, h_5CST
    • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
    • cp_1, bvpage1
    • co_hasquestionsanswers, tq_1
    • loc_zh_CN, sid_377175, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getContent, 112ms
    • QUESTIONS, PRODUCT
    Rated 1 out of 5 by from We were not able to detect any bands in WesternWe were not able to detect any bands in Western blot; our protocol has always worked fine.
    Date published: 2015-04-08
    Rated 5 out of 5 by from Immunofluorescence staining of methanolImmunofluorescence staining of methanol-fixed HeLa cells showed cytoplasmic localization. -SCBT QC
    Date published: 2015-02-06
    Rated 5 out of 5 by from Good detection in WB of Protein C expressionGood detection in WB of Protein C expression in human liver tissue extract and Hep G2, K-562 and ECV304 whole cell lysates. -SCBT QC
    Date published: 2013-05-14
    • y_2025, m_9, d_6, h_5
    • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
    • cp_1, bvpage1
    • co_hasreviews, tv_0, tr_3
    • loc_zh_CN, sid_377175, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getReviews, 27ms
    • REVIEWS, PRODUCT
    Protein C 抗体 (C-10) is rated 3.7 out of 5 by 3.
    • y_2025, m_9, d_6, h_5
    • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
    • cp_1, bvpage1
    • co_hasreviews, tv_0, tr_3
    • loc_zh_CN, sid_377175, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getAggregateRating, 124ms
    • REVIEWS, PRODUCT