Date published: 2025-9-6

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PRDM10 抗体 (48AT1224.90.46): sc-130240

4.5(2)
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说明书
  • PRDM10 抗体 48AT1224.90.46 是小鼠单克隆 IgG1PRDM10抗体,规格为100 µg/ml
  • 与human的PRDM10的N-terminal肽
  • 推荐用于 mouse, rat 和 human 来源的PRDM10 WB, IP 和 ELISA检测
  • 目前,我们还没有完成PRDM10 抗体 (48AT1224.90.46)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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    関連項目

    PRDM10抗体(48AT1224.90.46)是一种IgG1型小鼠单克隆PRDM10抗体(也称为PRDM10抗体),可通过WB、IP和ELISA检测小鼠、大鼠和人类来源的PRDM10蛋白。PRDM10抗体(48AT1224.90.46)为非偶联抗PRDM10抗体形式。含PR结构域的蛋白质(PRDMs)在调节基因活性方面具有共同作用。PR结构域家族成员通常产生两种产物,它们在是否存在PR结构域方面有所不同。PR阳性产物表达不足或受到破坏,而PR阴性产物在癌细胞中存在或过表达。这种两种产物数量上的不平衡是由遗传或表观遗传事件造成的,似乎是恶性肿瘤的决定性原因。研究表明,含PR结构域的蛋白PRDM10可能作为转录因子发挥作用。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    PRDM10 抗体 (48AT1224.90.46) 参考文献:

    1. 1p36连锁癌症中的视网膜母细胞瘤蛋白互作锌指基因RIZ。  |  Huang, S. 1999. Front Biosci. 4: D528-32. PMID: 10369808
    2. 预测人类不明基因的编码序列。XV.100 个新的大脑 cDNA 克隆的完整序列,它们在体外编码大型蛋白质。  |  Nagase, T., et al. 1999. DNA Res. 6: 337-45. PMID: 10574462
    3. PR-domain家族基因在肿瘤发生中的阴阳作用。  |  Jiang, GL. and Huang, S. 2000. Histol Histopathol. 15: 109-17. PMID: 10668202
    4. 生成并初步分析了 15,000 多个全长人类和小鼠 cDNA 序列。  |  Strausberg, RL., et al. 2002. Proc Natl Acad Sci U S A. 99: 16899-903. PMID: 12477932
    5. 斑马鱼prdm1/blimp1同源物在胚胎模式化和器官形成中的重要作用  |  Wilm, TP. and Solnica-Krezel, L. 2005. Development. 132: 393-404. PMID: 15623803
    6. 视网膜母细胞瘤互作锌指基因 RIZ 通过内部启动子产生缺乏 PR 结构域的产物。  |  Liu, L., et al. 1997. J Biol Chem. 272: 2984-91. PMID: 9006946

    订购信息

    产品名称产品编号规格价格数量收藏夹

    PRDM10 抗体 (48AT1224.90.46)

    sc-130240
    100 µg/ml
    $316.00

    For Western Blot, is it recommended to use denatured or non-denatured conditions with PRDM10 (48AT1224.90.46): sc-130240 antibody?

    Asked by: DefinitelyNotMatt
    Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
    Answered by: Technical Support
    Date published: 2017-03-27
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    Rated 5 out of 5 by from Good for multiple applicationsThis antibody can be used to detect PRDM10 by ELISA, Western Blot and Immunoprecipitation. -SCBT QC
    Date published: 2023-09-14
    Rated 4 out of 5 by from Strong band in western blot analysis of PRDM10Strong band in western blot analysis of PRDM10 expression in 293 whole cell lysates. -SCBT QC
    Date published: 2014-09-10
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    PRDM10 抗体 (48AT1224.90.46) is rated 4.5 out of 5 by 2.
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