Date published: 2025-9-9

021-6093-6350

SCBT Portrait Logo
Seach Input

PNP 抗体 (D-11): sc-271890

5.0(1)
寫評論提問

说明书
  • PNP 抗体 D-11 是小鼠单克隆 IgG1, 在1篇文献中引用,提供 200 µg/ml
  • 针对human起源的PNP内部区域内的氨基酸95-150进行
  • 推荐用于 mouse, rat, human 来源的PNP WB, IP, IF 和 ELISA检测
  • 1 BP-HRP">m-IgG1 BP-HRP是PNP Antibody (D-11) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与PNP Antibody (D-11) 打包提供(请参阅下面的订购信息)。

快捷链接

関連項目

嘌呤核苷磷酸化酶(PNP),也称为肌苷磷酸化酶,形成同源三聚体。它属于PNP/MTAP磷酸化酶蛋白家族。人PNP催化核糖核苷和2′-脱氧核糖核苷的可逆磷酸解,对鸟嘌呤、次黄嘌呤及其类似物具有特异性。PNP缺陷是一种罕见的常染色体隐性遗传病,与儿童T淋巴细胞功能和神经障碍的严重缺陷有关,占联合免疫缺陷病例的4%。PNP缺陷儿童极易感染、患自身免疫性疾病、神经功能障碍和癌症。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

PNP 抗体 (D-11) 参考文献:

  1. 人类PNP与鸟嘌呤的晶体结构。  |  de Azevedo, WF., et al. 2003. Biochem Biophys Res Commun. 312: 767-72. PMID: 14680831
  2. 人类 PNP 与配体复合物的结构。  |  Canduri, F., et al. 2005. Acta Crystallogr D Biol Crystallogr. 61: 856-62. PMID: 15983407
  3. 不含色氨酸的人类PNP揭示了催化位点的相互作用。  |  Ghanem, M., et al. 2008. Biochemistry. 47: 3202-15. PMID: 18269249
  4. 嘌呤核苷磷酸酶(PNP)过渡状态类似物抑制剂Immucillin-H可阻止大鼠牙周疾病模型中的骨丢失。  |  Deves, C., et al. 2013. Bone. 52: 167-75. PMID: 23026564
  5. 大鼠C6胶质瘤细胞中嘌呤核苷磷酸酶(PNP)释放的证据。  |  Giuliani, P., et al. 2017. J Neurochem. 141: 208-221. PMID: 28251649
  6. 磷酸二酯酶抑制剂选择性杀死缺乏SAMHD1的癌细胞。  |  Davenne, T. and Rehwinkel, J. 2020. Mol Cell Oncol. 7: 1804308. PMID: 33235905
  7. 使用血小板包裹纳米粒子的肿瘤内免疫疗法可增强实体瘤的抗肿瘤免疫力。  |  Bahmani, B., et al. 2021. Nat Commun. 12: 1999. PMID: 33790276
  8. AMP-PNP结合的人类线粒体ATP结合盒转运蛋白ABCB7的冷冻电子显微镜结构。  |  Yan, Q., et al. 2022. J Struct Biol. 214: 107832. PMID: 35041979
  9. "PNP减慢" - 多发性神经病患者的全身关节速度呈线性降低,步态模式也发生了变化。  |  Walz, ID., et al. 2023. Front Hum Neurosci. 17: 1229440. PMID: 37780958
  10. 人类诱导多能干细胞/胚胎干细胞衍生的锥体神经元前体在大鼠脊髓损伤模型中显示出安全性和有效性。  |  Li, M., et al. 2024. Cell Mol Life Sci. 81: 318. PMID: 39073571

订购信息

产品名称产品编号规格价格数量收藏夹

PNP 抗体 (D-11)

sc-271890
200 µg/ml
RMB2377.00

PNP (D-11): m-IgG1 BP-HRP 套装

sc-542684
200 µg Ab; 20 µg BP
RMB2662.00

I am using the LiCor/Odyssey system. Which secondary antibody do you recommend using with PNP (D-11): sc-271890?

Asked by: Dr Ninau Qelp
We recommend using one of our our exclusive Mouse IgG Binding Proteins conjugated to CFL 680 or CFL 790. They are suitable for use with Near-Infrared (NIR) detection systems, such as LI-COR/Odyssey and other comparable systems. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support
Date published: 2017-02-27
  • y_2025, m_9, d_7, h_4CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_zh_CN, sid_271890, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 138ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from Satisfactory Western blot data of PNP expressionSatisfactory Western blot data of PNP expression in non-transfected and human PNP transfected 293T whole cell lysates. -SCBT QC
Date published: 2014-08-01
  • y_2025, m_9, d_7, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_zh_CN, sid_271890, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 20ms
  • REVIEWS, PRODUCT
PNP 抗体 (D-11) is rated 5.0 out of 5 by 1.
  • y_2025, m_9, d_7, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_zh_CN, sid_271890, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 106ms
  • REVIEWS, PRODUCT