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plexin-B2 抗体 (A-5): sc-373969

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说明书
  • plexin-B2 抗体 A-5 是小鼠单克隆 IgM κ,plexin-B2抗体, 在2篇文献中引用,规格为200 µg/ml
  • 抗原表位位于human来源plexin-B2胞外域的1103-1136氨基酸之间
  • 推荐用于 mouse, rat 和 human 来源的plexin-B2 precursor and mature WB, IP, IF, IHC(P) 和 ELISA检测
  • 关于如何获取plexin-B2 (A-5): sc-373969免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgGκ BP-HRP 是 plexin-B2 抗体 (A-5) 在 WB and IHC(P) 应用中的首选二抗检测试剂。该试剂现与plexin-B2 抗体 (A-5) 组合成套装提供。 (请参阅下面的订购信息)。其他m-IgGκ BP 偶联产品,请参阅我们的小鼠 IgG 结合蛋白完整列表。

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関連項目

plexin-B2抗体(A-5)是一种IgM κ小鼠单克隆plexin-B2抗体(也称为PLXNB2抗体或MM1抗体),可通过WB、IP、IF、IHC(P)和ELISA检测小鼠、大鼠和人类来源的plexin-B2蛋白。plexin-B2抗体(A-5)以非偶联抗plexin-B2抗体的形式提供。Plexins是脊椎动物中多类信号蛋白的跨膜受体大家族。它们广泛表达,其细胞外结构域的区域与离散因子受体和信号蛋白结构域同源。Plexins可以单独作为信号蛋白受体,也可以与神经菌毛蛋白结合。Plexins分为四个亚家族,分别命名为plexin-A、-B、-C和-D。Plexin-B1和-B2都是Sema4D的受体,Sema4D刺激胚胎背根神经节神经元的轴突生长。Plexin-B3与Sema5A结合,Sema5A控制轴突导向,并可以启动肝细胞生长因子/离散因子受体Met的细胞内信号传导。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

plexin-B2 抗体 (A-5) 参考文献:

  1. Plexin-neuropilin-1 复合物形成功能性 semaphorin-3A 受体。  |  Takahashi, T., et al. 1999. Cell. 99: 59-69. PMID: 10520994
  2. 在脊椎动物中,Plexins 是跨膜, 分泌和 GPI-anchored semaphorins 受体的一个大家族。  |  Tamagnone, L., et al. 1999. Cell. 99: 71-80. PMID: 10520995
  3. Plexins, semaphorins和散射因子受体:细胞引导信号的共同根源?  |  Artigiani, S., et al. 1999. IUBMB Life. 48: 477-82. PMID: 10637762
  4. Plexin-B3 是 semaphorin 5A 的功能性受体。  |  Artigiani, S., et al. 2004. EMBO Rep. 5: 710-4. PMID: 15218527
  5. Sema4D 可刺激胚胎 DRG 感觉神经元的轴突生长。  |  Masuda, K., et al. 2004. Genes Cells. 9: 821-9. PMID: 15330859
  6. Plexin-B2 介导血管生成素的生理和病理功能  |  Yu, W., et al. 2017. Cell. 171: 849-864.e25. PMID: 29100074
  7. 麝香可通过激活血管生成素/Plexin-B2轴来改善脊髓损伤。  |  Zhou, Y., et al. 2022. Mol Neurobiol. 59: 5891-5901. PMID: 35809154
  8. Plexin B2(PLXNB2)中的双等位基因变异会导致牙釉质发育不全、听力损失和智力障碍。  |  Smith, CEL., et al. 2024. J Med Genet. 61: 689-698. PMID: 38458752
  9. semaphorin基因编码一系列跨膜和分泌型生长锥导向分子。  |  Kolodkin, AL., et al. 1993. Cell. 75: 1389-99. PMID: 8269517
  10. 鉴定小鼠中的丛神经蛋白家族分子。  |  Kameyama, T., et al. 1996. Biochem Biophys Res Commun. 226: 396-402. PMID: 8806646
  11. 肝细胞生长因子(HGF)和相关散射因子对侵入性生长的控制。  |  Tamagnone, L. and Comoglio, PM. 1997. Cytokine Growth Factor Rev. 8: 129-42. PMID: 9244408
  12. Plexin A 是一种控制轴突导向的神经元半影素受体。  |  Winberg, ML., et al. 1998. Cell. 95: 903-16. PMID: 9875845

订购信息

产品名称产品编号规格价格数量收藏夹

plexin-B2 抗体 (A-5)

sc-373969
200 µg/ml
RMB2377.00

plexin-B2 (A-5): m-IgGκ BP-HRP 套装

sc-522573
200 µg Ab, 40 µg BP
RMB2662.00

plexin-B2 (A-5) 中和勝肽

sc-373969 P
100 µg/0.5 ml
RMB511.00

What application is the blocking peptide sc-373969 P appropriate for?

Asked by: cjMara
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-25
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Rated 5 out of 5 by from Beautiful immunoperoxidase cytoplasmic andBeautiful immunoperoxidase cytoplasmic and nuclear staining in formalin fixed, paraffin-embedded human pancreas tissue. -SCBT QC
Date published: 2015-05-13
Rated 5 out of 5 by from Great Western Blot data of plexinGreat Western Blot data of plexin-B2 expression in 293T whole cell lysate and mouse brain tissue extract . -SCBT QC
Date published: 2014-05-28
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plexin-B2 抗体 (A-5) is rated 5.0 out of 5 by 2.
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