Date published: 2025-9-8

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PLAC1 抗体 (G-1): sc-365919

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说明书
  • PLAC1 抗体 G-1 是小鼠单克隆 IgG1 κ,PLAC1抗体, 在6篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列65-212位于human物种的PLAC1的C-terminus
  • PLAC1 抗体 (G-1) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 PLAC1
  • 抗PLAC1抗体(G-1)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取PLAC1 (G-1): sc-365919免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgGκ BP-HRP 是 PLAC1 抗体 (G-1) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与PLAC1 抗体 (G-1) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

PLAC1 Antibody (G-1)是一种IgG1 κ型小鼠单克隆PLAC1抗体(也称为PLAC1抗体),通过WB、IP、IF、IHC(P)和ELISA检测小鼠、大鼠和人源PLAC1蛋白。PLAC1抗体(G-1)既可以是非偶联的抗PLAC1抗体形式,也可以是多种偶联的抗PLAC1抗体形式,包括琼脂糖、HRP、PE、FITC和Alexa Fluor®的多种偶联物。胎盘特异性蛋白(PLACs)是x连锁蛋白。Plac1基因定位于X染色体上一个已知对胎盘生长很重要的区域。Plac1显示胎盘特异性表达,被认为是胎盘发育的标志物。PLAC1可能在建立母-胎界面中发挥作用,且仅在滋养层细胞中表达。PLAC1在滋养细胞分化过程中表达上调,其表达受肽生长因子调节。在母体血液中可检测到,但在分娩后迅速消失。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

PLAC1 抗体 (G-1) 参考文献:

  1. PLAC1,一个具有胎盘特异性表达的 Xq26 基因。  |  Cocchia, M., et al. 2000. Genomics. 68: 305-12. PMID: 10995572
  2. PLAC1是滋养细胞特异性基因,在人类胎盘的整个妊娠过程中都有表达,并受角质细胞生长因子的调节。  |  Fant, M., et al. 2002. Mol Reprod Dev. 63: 430-6. PMID: 12412044
  3. 在阴道出血(20 周以内的威胁流产)和胎儿存活的孕妇中,母体 PLAC1 mRNA 较低。  |  Farina, A., et al. 2005. Clin Chem. 51: 224-7. PMID: 15516331
  4. 分娩后母体血液中 PLAC1 基因的 mRNA 快速清除。  |  Concu, M., et al. 2005. Fetal Diagn Ther. 20: 27-30. PMID: 15608456
  5. 滋养细胞分化过程中 PLAC1 表达增加:与成纤维细胞生长因子-7(FGF-7)轴相互作用的证据。  |  Massabbal, E., et al. 2005. Mol Reprod Dev. 71: 299-304. PMID: 15803460
  6. PLAC1免疫不会导致小鼠不育。  |  Liso, A., et al. 2017. Immunotherapy. 9: 481-486. PMID: 28351180
  7. Plac1在小鼠母胎界面上的表达模式及其在滋养层细胞分化中的作用。  |  Gu, Y., et al. 2017. Cell Physiol Biochem. 43: 2001-2009. PMID: 29055961
  8. 作为乳腺癌血清生物标志物的 PLAC1  |  Yuan, H., et al. 2018. PLoS One. 13: e0192106. PMID: 29432428
  9. PLAC1对于FGF7/FGFRIIIb诱导的Akt介导的癌细胞增殖至关重要。  |  Roldán, DB., et al. 2020. Oncotarget. 11: 1862-1875. PMID: 32499871
  10. Plac1通过Furin/NICD/PTEN途径促进鼻咽癌细胞的增殖、迁移和侵袭。  |  Lin, C., et al. 2021. Tissue Cell. 69: 101480. PMID: 33418237
  11. PLAC1通过抑制滋养层细胞凋亡来调节胎儿生长受限的发生。  |  Sun, D., et al. 2021. Ann Clin Lab Sci. 51: 182-189. PMID: 33941557
  12. PLAC1 通过与脱模小体复合物相互作用,影响细胞间的交流。  |  Chen, Y., et al. 2021. Placenta. 110: 39-45. PMID: 34118612

订购信息

产品名称产品编号规格价格数量收藏夹

PLAC1 抗体 (G-1)

sc-365919
200 µg/ml
RMB2377.00

PLAC1 (G-1): m-IgG Fc BP-HRP 套装

sc-529511
200 µg Ab; 10 µg BP
RMB2662.00

PLAC1 (G-1): m-IgGκ BP-HRP 套装

sc-522421
200 µg Ab, 40 µg BP
RMB2662.00

PLAC1 抗体 (G-1) AC

sc-365919 AC
500 µg/ml, 25% agarose
RMB3129.00

PLAC1 抗体 (G-1) HRP

sc-365919 HRP
200 µg/ml
RMB2377.00

PLAC1 抗体 (G-1) FITC

sc-365919 FITC
200 µg/ml
RMB2482.00

PLAC1 抗体 (G-1) PE

sc-365919 PE
200 µg/ml
RMB2580.00

PLAC1 抗体 (G-1) Alexa Fluor® 488

sc-365919 AF488
200 µg/ml
RMB2685.00

PLAC1 抗体 (G-1) Alexa Fluor® 546

sc-365919 AF546
200 µg/ml
RMB2685.00

PLAC1 抗体 (G-1) Alexa Fluor® 594

sc-365919 AF594
200 µg/ml
RMB2685.00

PLAC1 抗体 (G-1) Alexa Fluor® 647

sc-365919 AF647
200 µg/ml
RMB2685.00

PLAC1 抗体 (G-1) Alexa Fluor® 680

sc-365919 AF680
200 µg/ml
RMB2685.00

PLAC1 抗体 (G-1) Alexa Fluor® 790

sc-365919 AF790
200 µg/ml
RMB2685.00

i want to use a microfluidic chip for detection PLAC1, so i should use somethings called beads in this chip. i want to know that can i use your antbody against plc1 which is coated on the beads for this application? thanks alot.

Asked by: elaheh em
Thank you for your question. We have not tested this antibody in that application so we can not make any recommendation at this time.
Answered by: Technical Support
Date published: 2023-07-23

I am using PLAC1 (G-1): sc-365919 monoclonal antibody to stain paraffin embedded tissue. Do you recommend antigen retrieval when using this antibody?

Asked by: Germaine
We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from 免疫组化结果非常好结果符合预期,使用非常好,即将购买大包装。背景清晰,染色好看,区分度明显。使用方便,提供试用装非常棒。
Date published: 2020-05-29
Rated 5 out of 5 by from Excellent!This antibody is great in western blot analysis of PLAC1 expression in RAW 264.7, KNRK and RBL-1 whole cell lysates.
Date published: 2017-01-24
Rated 5 out of 5 by from Produced nice Western blot data of PLAC1Produced nice Western blot data of PLAC1 expression in JEG-3 whole cell lysate. -SCBT QC
Date published: 2013-05-22
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PLAC1 抗体 (G-1) is rated 5.0 out of 5 by 3.
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