Date published: 2025-9-7

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PKAα/β/γ cat 抗体 (G-6): sc-390548

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说明书
  • PKAα/β/γ cat抗体(G-6)是小鼠单克隆IgG1 κ, 在13篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列231-286位于human物种的PKAα catalytic subunit的C-terminus附近
  • PKA alpha / beta / gamma cat 抗体 (G-6) 推荐用于 WB, IP, IF 和 ELISA,检测 PKAα/β cat of mouse, rat and human origin, and PKAγ cat of human origin ; 也和以下物种反应,包括: 和 equine, canine, bovine and porcine
  • 抗PKA alpha / beta / gamma cat抗体(G-6)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取PKAα/β/γ cat (G-6): sc-390548免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是PKAα/β/γ cat Antibody (G-6) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与PKAα/β/γ cat Antibody (G-6) 打包提供(请参阅下面的订购信息)。

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関連項目

PKAα/β/γ cat抗体(G-6)是一种IgG1 κ小鼠单克隆PKAα/β/γ cat抗体(也称为PKAα/β/γ cat抗体或PRKACA、PRKACB、PRKACG抗体),可通过WB、IP、IF和ELISA检测小鼠、大鼠和人类来源的PKAα/β cat,以及人源PKAγ cat。PKAα/β/γ cat抗体(G-6)既可作为非偶联抗PKAα/β/γ cat抗体形式提供,也可作为多种偶联形式的抗PKAα/β/γ cat抗体提供,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。第二信使环磷酸腺苷(cAMP)通过激活cAMP依赖性蛋白激酶(cAPKs或PKAs),介导细胞对外部信号的各种反应,如增殖、离子转运、代谢调节和基因转录。当cAMP与四聚体PKA全酶的两个调节亚基结合时,PKA被激活,从而释放出活性催化亚基。PKA全酶存在三种催化亚基,分别命名为PKAα cat、PKAβ cat和PKAγ cat,每种都代表特定的基因产物。PKAα cat和PKAβ cat密切相关(93%的氨基酸序列相似性),而PKAγ cat与PKAα cat和PKAβ cat的相似性分别为83%和79%。cAMP水平升高导致转录激活的原因是PKA易位至细胞核,在细胞核中它磷酸化CREB,导致TFIIB-TBP1结合,最终将磷酸化CREB与Pol II转录起始复合物连接起来。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

订购信息

产品名称产品编号规格价格数量收藏夹

PKAα/β/γ cat 抗体 (G-6)

sc-390548
200 µg/ml
RMB2377.00

PKAα/β/γ cat (G-6): m-IgG Fc BP-HRP 套装

sc-530187
200 µg Ab; 10 µg BP
RMB2662.00

PKAα/β/γ cat (G-6): m-IgGκ BP-HRP 套装

sc-523580
200 µg Ab, 40 µg BP
RMB2662.00

PKAα/β/γ cat (G-6): m-IgG1 BP-HRP 套装

sc-543914
200 µg Ab; 20 µg BP
RMB2662.00

PKAα/β/γ cat 抗体 (G-6) AC

sc-390548 AC
500 µg/ml, 25% agarose
RMB3129.00

PKAα/β/γ cat 抗体 (G-6) HRP

sc-390548 HRP
200 µg/ml
RMB2377.00

PKAα/β/γ cat 抗体 (G-6) FITC

sc-390548 FITC
200 µg/ml
RMB2482.00

PKAα/β/γ cat 抗体 (G-6) PE

sc-390548 PE
200 µg/ml
RMB2580.00

PKAα/β/γ cat 抗体 (G-6) Alexa Fluor® 488

sc-390548 AF488
200 µg/ml
RMB2685.00

PKAα/β/γ cat 抗体 (G-6) Alexa Fluor® 546

sc-390548 AF546
200 µg/ml
RMB2685.00

PKAα/β/γ cat 抗体 (G-6) Alexa Fluor® 594

sc-390548 AF594
200 µg/ml
RMB2685.00

PKAα/β/γ cat 抗体 (G-6) Alexa Fluor® 647

sc-390548 AF647
200 µg/ml
RMB2685.00

PKAα/β/γ cat 抗体 (G-6) Alexa Fluor® 680

sc-390548 AF680
200 µg/ml
RMB2685.00

PKAα/β/γ cat 抗体 (G-6) Alexa Fluor® 790

sc-390548 AF790
200 µg/ml
RMB2685.00

I need to use an antibody to detect the protein in samples of bovine origin. Do you know if this mouse monoclonal antibody will work?

Asked by: jerojero
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support 2
Date published: 2017-07-07
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Rated 5 out of 5 by from western blotI used this antibody in western blot (dilution 1:500), second antibody is 1:5000.
Date published: 2017-06-07
Rated 5 out of 5 by from Good WB detectionA good choice for WB detection of multiple PKA isoforms. It has broad reactivity and will provide clear and specific signal at the appropriate molecular weight. This antibody has been published with.
Date published: 2017-02-02
Rated 5 out of 5 by from Produced positive Western Blot data of PKAProduced positive Western Blot data of PKA / / cat expression in human testis tissue extract and Hs 181 Tes, NTERA-2 cl.D1 and KNRK whole cell lysates. -SCBT QC
Date published: 2015-04-26
Rated 5 out of 5 by from Great Western Blot data of PKA / / cat expressionGreat Western Blot data of PKA / / cat expression in NIH/3T3 and PC-3 whole cell lysates and mouse brain and human hippocampus tissue extracts. -SCBT QC
Date published: 2013-10-27
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PKAα/β/γ cat 抗体 (G-6) is rated 5.0 out of 5 by 4.
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