Piperazine CAS: 110-85-0
MF: C4H10N2
MW: 86.14
A buffer component in chromatography purifications and separations based on pH.

Piperazine (CAS 110-85-0)

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Alternate Names: 1,4-Diazacyclohexane; Diethylenediamine
Application: Piperazine is a buffer component in chromatography purifications and separations based on pH
CAS Number: 110-85-0
Molecular Weight: 86.14
Molecular Formula: C4H10N2
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).
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Buffer component; the pH of a 10% aqueous solution is 10.8-11.8. Used as a buffer component in chromatography purifications and/or separations based on pH. The piperazine scaffold is frequently found in biologically active compounds across a number of different therapeutic areas. Some therapeutic areas include antifungals, antidepressants, antiviral, and serotonin receptor (5-HT) antagonists/agonists. Has been used since the 1950's as an anthelmintic, especially in horses and dogs. The anthelmintic properties of piperazine compounds is by paralysis of the parasites; this action is mediated by its agonistic effects on the GABA receptor. Wide variety of additional applications include use as an intermediate for pharmaceuticals, polymers, dyes, corrosion inhibitors, rubber accelerators and surfactants.


参考文献

1. Blechschmidt, B., et al. 1992. J. Gen. Microbiol. 138: 1197-1202. PMID: 1527494
2. Jones, R.G., et al. 2002. J. Immunol. Methods. 263: 57-74. PMID: 12009204

Usage :
Turns dark on exposure to light. Piperazine readily absorbs water and carbon dioxide from the air.
Physical State :
Solid
Storage :
Store at room temperature
Melting Point :
109-112° C (lit.)
Boiling Point :
145-146° C (lit.)
仅供科研使用。不可用于诊断或治疗。
PubChem CID :
4837
SMILES :
C1CNCCN1

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