Date published: 2025-9-7

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Peripherin 抗体 (A-3): sc-377093

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说明书
  • Peripherin 抗体 A-3 是小鼠单克隆 IgG2a κ,Peripherin抗体, 在20篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列21-90位于human物种的Peripherin的N-terminus附近
  • Peripherin 抗体 (A-3) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 Peripherin
  • 抗Peripherin抗体(A-3)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取Peripherin (A-3): sc-377093免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgG2a BP-HRP 是 Peripherin 抗体 (A-3) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与Peripherin 抗体 (A-3) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

Peripherin抗体(A-3)是一种IgG2a κ小鼠单克隆Peripherin抗体(也称为PERI抗体、PRPH1抗体、NEF4抗体、神经丝蛋白4(57kD)抗体或神经丝蛋白4抗体),可通过WB、IP、IF、IHC(P)和ELISA检测小鼠、大鼠和人类来源的Peripherin蛋白。Peripherin抗体(A-3)既可作为非偶联抗Peripherin抗体,也可作为多种偶联形式的抗Peripherin抗体,包括琼脂糖偶联、辣根过氧化物酶(HRP)偶联、藻红蛋白(PE)偶联、异硫氰酸荧光素(FITC)偶联和多种Alexa Fluor®偶联物。Peripherin是一种III型中间丝蛋白(IFP),在外周和一些中枢神经系统(CNS)神经元中表达。已知白血病抑制因子(LIF)可诱导Peripherin活化。LIF通过诱导Stat转录因子家族成员与Peripherin基因中的特定启动子元件结合来激活Peripherin。IL-6也被认为可以诱导Peripherin表达。虽然它不是神经突起形成所必需的,但Peripherin对于细胞中间丝网络的形成是必需的。与大多数中间丝蛋白不同,Peripherin已被报道被酪氨酸磷酸化修饰。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Peripherin 抗体 (A-3) 参考文献:

  1. 对耳蜗神经元中外周蛋白表达的新见解。  |  Lallemend, F., et al. 2007. Neuroscience. 150: 212-22. PMID: 17964735
  2. 外周蛋白-IgG与神经和内分泌自身免疫有关。  |  Chamberlain, JL., et al. 2010. J Autoimmun. 34: 469-77. PMID: 20061119
  3. 外周蛋白是周围神经神经丝的亚基:对中枢神经系统和周围神经系统轴突不同脆弱性的影响。  |  Yuan, A., et al. 2012. J Neurosci. 32: 8501-8. PMID: 22723690
  4. ALS相关外周蛋白拼接转录物形成独特的蛋白质包涵体,对氧化应激具有神经保护作用。  |  McLean, JR., et al. 2014. Exp Neurol. 261: 217-29. PMID: 24907400
  5. 编码 peripherin(一种受 NGF 调节的神经元特异性 III 型中间丝蛋白)基因的结构。  |  Thompson, MA. and Ziff, EB. 1989. Neuron. 2: 1043-53. PMID: 2624740
  6. 发现磷酸化外周蛋白是1型糖尿病的主要体液自身抗原。  |  Doran, TM., et al. 2016. Cell Chem Biol. 23: 618-628. PMID: 27185639
  7. 外周蛋白2和Rom-1对视网膜色素变性相关外周蛋白2突变体的杆状体外段靶向具有相反的作用。  |  Böhm, S., et al. 2017. Sci Rep. 7: 2321. PMID: 28539581
  8. 外周蛋白在 SW13 细胞中组装成均聚物。  |  Cui, C., et al. 1995. J Cell Sci. 108 (Pt 10): 3279-84. PMID: 7593288
  9. 白细胞介素-6能诱导外周蛋白的表达,并与Trk受体信号合作促进PC12细胞的神经元分化。  |  Sterneck, E., et al. 1996. J Neurochem. 67: 1365-74. PMID: 8858917
  10. 在转基因小鼠胚胎中,小鼠周皮素基因的细胞类型特异性表达需要上游序列和基因内序列。  |  Leconte, L., et al. 1996. Brain Res Dev Brain Res. 92: 1-9. PMID: 8861716
  11. 外周蛋白在其羧基末端的酪氨酸处被酪氨酸磷酸化。  |  Angelastro, JM., et al. 1998. J Neurochem. 70: 540-9. PMID: 9453548
  12. 白血病抑制因子对小鼠周皮素基因的转录激活:STAT 蛋白的参与。  |  Lecomte, MJ., et al. 1998. J Neurochem. 70: 971-82. PMID: 9489716

订购信息

产品名称产品编号规格价格数量收藏夹

Peripherin 抗体 (A-3)

sc-377093
200 µg/ml
RMB2377.00

Peripherin (A-3): m-IgG Fc BP-HRP 套装

sc-526079
200 µg Ab; 10 µg BP
RMB2662.00

Peripherin (A-3): m-IgG2a BP-HRP 套装

sc-546497
200 µg Ab; 10 µg BP
RMB2662.00

Peripherin 抗体 (A-3) AC

sc-377093 AC
500 µg/ml, 25% agarose
RMB3129.00

Peripherin 抗体 (A-3) HRP

sc-377093 HRP
200 µg/ml
RMB2377.00

Peripherin 抗体 (A-3) FITC

sc-377093 FITC
200 µg/ml
RMB2482.00

Peripherin 抗体 (A-3) PE

sc-377093 PE
200 µg/ml
RMB2580.00

Peripherin 抗体 (A-3) Alexa Fluor® 488

sc-377093 AF488
200 µg/ml
RMB2685.00

Peripherin 抗体 (A-3) Alexa Fluor® 546

sc-377093 AF546
200 µg/ml
RMB2685.00

Peripherin 抗体 (A-3) Alexa Fluor® 594

sc-377093 AF594
200 µg/ml
RMB2685.00

Peripherin 抗体 (A-3) Alexa Fluor® 647

sc-377093 AF647
200 µg/ml
RMB2685.00

Peripherin 抗体 (A-3) Alexa Fluor® 680

sc-377093 AF680
200 µg/ml
RMB2685.00

Peripherin 抗体 (A-3) Alexa Fluor® 790

sc-377093 AF790
200 µg/ml
RMB2685.00

Hello, Is it possible to get this antibody (Peripherin Antibody (A-3): sc-377093) carrier free? It currently has gelatin in the storage buffer.

Asked by: Anonymous
Thank you for your question. Please contact our special orders department for a price quote and ship date . Please email [email protected].
Answered by: BlakeJ
Date published: 2025-02-07

Do you still have lot#H0112 for this antibody? If yes, how many left? Thank you.

Asked by: fu800531
Thank you for your question. Please contact our Customer Care Department for current product availability, and to request a specific lot number.
Answered by: Technical Support
Date published: 2019-02-27

I am using Peripherin (A-3): sc-377093 monoclonal antibody to stain paraffin embedded tissue. Do you recommend antigen retrieval when using this antibody?

Asked by: Trav11
We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Excelentes resultadosIncreíbles resultados en extracto total de células PC12, en western blot funcionó en 1:1000 y para inmunofluorescencia indirecta 1:300
Date published: 2024-04-15
Rated 5 out of 5 by from Neuronal marker-myenteric plexi and cleared colonI have used this peripherin antibody, works great at 1:500 dilution for cleared colon tissue (CLARITY staining) and also with isolated myenteric plexi from colon.
Date published: 2022-03-28
Rated 4 out of 5 by from 大鼠肺组织good.........................................................
Date published: 2017-09-28
Rated 5 out of 5 by from Great immunoperoxidase cytoplasmic and membraneGreat immunoperoxidase cytoplasmic and membrane staining in formalin fixed, paraffin-embedded human colon tissue. -SCBT QC
Date published: 2015-05-04
Rated 5 out of 5 by from CrispCrisp, clean band using SK-N-SH whole cell lysate for western blot. -SCBT QC
Date published: 2015-03-24
Rated 5 out of 5 by from Strong band in WB using AStrong band in WB using A-3 in IMR-32 whole cell lysate. -SCBT QC
Date published: 2015-01-20
Rated 5 out of 5 by from Robust signal in western blot analysis ofRobust signal in western blot analysis of Peripherin expression in PC-12 whole cell lysate. -SCBT QC
Date published: 2015-01-14
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Peripherin 抗体 (A-3) is rated 4.9 out of 5 by 7.
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