Date published: 2025-9-7

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PCDH1 抗体 (B-11): sc-398263

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说明书
  • PCDH1 抗体 B-11 是小鼠单克隆 IgG1 κ,PCDH1抗体, 在1篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列237-329位于human物种的PCDH1的N-terminus附近
  • PCDH1 抗体 (B-11) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 PCDH1
  • 抗PCDH1抗体(B-11)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取PCDH1 (B-11): sc-398263免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 1 BP-HRP">m-IgG1 BP-HRP是PCDH1 Antibody (B-11) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与PCDH1 Antibody (B-11) 打包提供(请参阅下面的订购信息)。

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関連項目

PCDH1抗体(B-11)是一种IgG1 κ小鼠单克隆PCDH1抗体(也称为PCDH1抗体),可通过WB、IP、IF和ELISA方法检测小鼠、大鼠和人类来源的PCDH1蛋白。PCDH1抗体(B-11)既可作为非偶联抗PCDH1抗体形式提供,也可作为多种偶联形式的抗PCDH1抗体提供,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。原钙粘蛋白是钙粘蛋白的一个亚家族,是一大类相关糖蛋白,通过嗜同性机制介导钙依赖性细胞间粘附。原钙粘蛋白参与多种功能,有助于调节神经发育和突触形成。PCDH1(原钙粘蛋白1),也称为PC42或PCDH42,是一种含有1026个氨基酸的单次跨膜I型膜蛋白,包含七个钙粘蛋白结构域,是原钙粘蛋白家族的成员。PCDH1定位于细胞-细胞和细胞-基质边界,在脑和神经胶质细胞中高水平表达,被认为参与细胞粘附和细胞间相互作用,并可能在神经元发育中发挥作用。由于选择性剪接事件,PCDH1包含一个C端细胞质区域、一个细胞外区域和一个跨膜区域,并表达为两种同工型。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

PCDH1 抗体 (B-11) 参考文献:

  1. 编码多个外显子的大外显子是原粘连蛋白基因的一个特征。  |  Wu, Q. and Maniatis, T. 2000. Proc Natl Acad Sci U S A. 97: 3124-9. PMID: 10716726
  2. 钙粘蛋白超家族基因:功能, 基因组组织和神经系统多样性。  |  Yagi, T. and Takeichi, M. 2000. Genes Dev. 14: 1169-80. PMID: 10817752
  3. 通过对粘附素超家族的系统进化分析,可以确定除了几个单独的成员外,还有六个主要的亚家族。  |  Nollet, F., et al. 2000. J Mol Biol. 299: 551-72. PMID: 10835267
  4. 原粘连蛋白-α的细胞质结构域可增强亲同性相互作用并识别细胞骨架元素。  |  Triana-Baltzer, GB. and Blank, M. 2006. J Neurobiol. 66: 393-407. PMID: 16408303
  5. 发育中大鼠大脑中非聚类原粘连蛋白家族成员的时空表达模式  |  Kim, SY., et al. 2007. Neuroscience. 147: 996-1021. PMID: 17614211
  6. 原粘连蛋白:中枢神经系统中与粘连蛋白相关的分子大家族。  |  Sano, K., et al. 1993. EMBO J. 12: 2249-56. PMID: 8508762
  7. 新型粘连蛋白相关蛋白原粘连蛋白-3 的克隆, 表达和染色体定域。  |  Sago, H., et al. 1995. Genomics. 29: 631-40. PMID: 8575755

订购信息

产品名称产品编号规格价格数量收藏夹

PCDH1 抗体 (B-11)

sc-398263
200 µg/ml
RMB2377.00

PCDH1 (B-11): m-IgG1 BP-HRP 套装

sc-531766
200 µg Ab; 20 µg BP
RMB2662.00

PCDH1 抗体 (B-11) AC

sc-398263 AC
500 µg/ml, 25% agarose
RMB3129.00

PCDH1 抗体 (B-11) HRP

sc-398263 HRP
200 µg/ml
RMB2377.00

PCDH1 抗体 (B-11) FITC

sc-398263 FITC
200 µg/ml
RMB2482.00

PCDH1 抗体 (B-11) PE

sc-398263 PE
200 µg/ml
RMB2580.00

PCDH1 抗体 (B-11) Alexa Fluor® 488

sc-398263 AF488
200 µg/ml
RMB2685.00

PCDH1 抗体 (B-11) Alexa Fluor® 546

sc-398263 AF546
200 µg/ml
RMB2685.00

PCDH1 抗体 (B-11) Alexa Fluor® 594

sc-398263 AF594
200 µg/ml
RMB2685.00

PCDH1 抗体 (B-11) Alexa Fluor® 647

sc-398263 AF647
200 µg/ml
RMB2685.00

PCDH1 抗体 (B-11) Alexa Fluor® 680

sc-398263 AF680
200 µg/ml
RMB2685.00

PCDH1 抗体 (B-11) Alexa Fluor® 790

sc-398263 AF790
200 µg/ml
RMB2685.00

Does this antibody work for detection of PCDH1 in mouse cells by immunofluorescence?

Asked by: RaoS
This primary antibody is recommended and warrantied for IF, or immunofluorescence detection in fresh or frozen tissues or cells, fixed in methanol or acetone. However we are still gathering data to show on our website. Check back for updates!
Answered by: Technical Support
Date published: 2018-12-21

I need to use an antibody to detect the protein in samples of porcine origin. Do you know if PCDH1 (B-11): sc-398263 mouse monoclonal antibody will work?

Asked by: Professor Griffin
Thank you for your inquiry. Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity. We are available by phone, e-mail or chat.
Answered by: Technical Support
Date published: 2017-02-28
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Rated 4 out of 5 by from Works wellWe have this antibody in our lab and found it works well.
Date published: 2017-05-18
Rated 5 out of 5 by from Great Western blot data of PCDH1 expression in nonGreat Western blot data of PCDH1 expression in non-transfected and human PCDH1 transfected 293T whole cell lysates. -SCBT QC
Date published: 2013-04-18
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PCDH1 抗体 (B-11) is rated 4.5 out of 5 by 2.
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