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paxillin 抗体 (C-1): sc-373880

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说明书
  • paxillin抗体(C-1)是小鼠单克隆IgG2a κ, 在5篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的paxillin的N-terminus附近的氨基酸17-47之间
  • 推荐用于 mouse, rat 和 human 来源的α,β, γ isoforms of paxillin WB, IP, IF 和 ELISA检测; 也和以下物种反应,包括: 和 equine and canine
  • 看 paxillin (B-2): sc-365379,可查看有标记的 paxillin 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 2a BP-HRP">m-IgG2a BP-HRPm-IgGκ BP-HRP是paxillin Antibody (C-1) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与paxillin Antibody (C-1) 打包提供(请参阅下面的订购信息)。

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Paxillin是一种位于细胞骨架的粘着斑磷酸蛋白。已经证明,Paxillin的磷酸化发生在PDGF治疗、v-src转化或整合素交联反应中。FAK(粘着斑激酶)和PYK2已被证明可以磷酸化paxillin。FAK在体外特异性磷酸化paxillin的Tyr 118。然而,FAK磷酸化似乎不是paxillin募集到细胞粘附位点所必需的。Paxillin可能在信号转导、细胞形态调节以及结构和信号分子募集到粘着斑中发挥作用。已经证明,有丝分裂细胞中paxillin的量通过蛋白水解下调而减少,并且paxillin在有丝分裂过程中可选择性地磷酸化丝氨酸而不是酪氨酸和丝氨酸。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

paxillin 抗体 (C-1)

sc-373880
200 µg/ml
RMB2377.00

paxillin (C-1): m-IgGκ BP-HRP 套装

sc-535324
200 µg Ab; 40 µg BP
RMB2662.00

paxillin (C-1): m-IgG2a BP-HRP 套装

sc-546221
200 µg Ab; 10 µg BP
RMB2662.00

paxillin (C-1) 中和勝肽

sc-373880 P
100 µg/0.5 ml
RMB511.00

What application is the blocking peptide sc-373880 P appropriate for?

Asked by: cjMara
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-25
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Rated 5 out of 5 by from Used this antibody to publish for use inUsed this antibody to publish for use in WB in porcine retina Muller cells.
Date published: 2015-09-11
Rated 4 out of 5 by from Performs well in WesternPerforms well in Western, good signal strength in HISM, ECV304 and CCD-1064Sk whole cell lysates. -SCBT QC
Date published: 2015-05-05
Rated 5 out of 5 by from Publishable WB data with rat nerve tissuePublishable WB data with rat nerve tissue - SCBT Publication Review
Date published: 2015-01-06
Rated 5 out of 5 by from WB publishable data with human OVCARWB publishable data with human OVCAR-3 cells - SCBT Publication Review
Date published: 2014-03-13
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paxillin 抗体 (C-1) is rated 4.8 out of 5 by 4.
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