Date published: 2025-9-8

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Pax-6 抗体 (AD2.38): sc-32766

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说明书
  • Pax-6抗体(AD2.38)是小鼠单克隆IgG1 λ, 在31篇文献中引用,规格为200 µg/ml
  • 免疫human来源Pax-6位于N-terminus 的1-206氨基酸
  • 抗-Pax-6 抗体 (AD2.38) 推荐用于 WB, IP, IF 和 IHC(P),检测mouse, rat 和human 来源的 Pax-6
  • 抗Pax-6抗体(AD2.38)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 可用于凝胶迁移和ChIP的TransCruz试剂(sc-32766 X, 200 µg/0.1 ml)
  • 关于如何获取Pax-6 (AD2.38): sc-32766免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgGλ BP-HRP (mouse IgGλ binding protein-HRP)是 Pax-6 抗体 (AD2.38) 在 WB and IHC(P) 应用中的首选二抗检测试剂。该试剂现与Pax-6 抗体 (AD2.38) 组合成套装提供。 (请参阅下面的订购信息)。其他m-IgGλ BP 偶联产品,请参阅我们的 小鼠 IgG 结合蛋白完整列表。

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関連項目

Pax-6抗体(AD2.38)是一种小鼠单克隆IgG1抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和免疫组织化学等方法检测小鼠、大鼠和人类样本中的Pax-6。抗Pax-6抗体(AD2.38)有非结合型和多种结合型,包括琼脂糖、辣根过氧化物酶(HRP)、藻红蛋白(PE)、异硫氰酸荧光素(FITC)和多种Alexa Fluor®结合物。Pax-6在眼睛发育中起着至关重要的作用,它作为转录调节因子与特定的DNA序列结合,从而控制对眼部结构形成至关重要的基因的表达。 Pax-6基因的突变或缺失可导致严重的先天性眼部疾病,包括无虹膜(特征为没有虹膜)和彼得斯异常(涉及角膜混浊和其他前段畸形)。Pax-6的结构包括一个由两个不同的DNA结合子域组成的配对域,能够有效识别和结合目标基因,从而影响对眼睛形成至关重要的发育途径。人类Pax-6基因产生两种可替代剪接的同工型,每种同工型都有独特的结构特征,有助于胚胎发育过程中的调节功能。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Pax-6 抗体 (AD2.38) 参考文献:

  1. Pax-6是胎儿大鼠丘脑皮层通路形成所必需的。  |  Kawano, H., et al. 1999. J Comp Neurol. 408: 147-60. PMID: 10333267
  2. Pax-6调节发育中中枢神经系统的SFRP-2和Wnt-7b的表达。  |  Kim, AS., et al. 2001. J Neurosci. 21: RC132. PMID: 11222670
  3. Pax-6在晶状体再生中的作用。  |  Madhavan, M., et al. 2006. Proc Natl Acad Sci U S A. 103: 14848-53. PMID: 17003134
  4. Pax-6 在角膜上皮模型系统分化的早期就已表达。  |  García-Villegas, R., et al. 2009. J Cell Physiol. 220: 348-56. PMID: 19347868
  5. 使用电化学发光免疫测定法定量眼压印细胞学样本中的Pax-6蛋白。  |  Zaworski, PG., et al. 2022. Anal Biochem. 656: 114876. PMID: 36058293
  6. Pax-6在眼睛和鼻子的发育中的作用。  |  Grindley, JC., et al. 1995. Development. 121: 1433-42. PMID: 7789273
  7. Pax-6同源框基因在角膜和结膜上皮中表达。  |  Koroma, BM., et al. 1997. Invest Ophthalmol Vis Sci. 38: 108-20. PMID: 9008636
  8. Pax-6在胚胎小鼠前脑的边界形成和轴突引导中发挥作用。  |  Mastick, GS., et al. 1997. Development. 124: 1985-97. PMID: 9169845
  9. Pax-6参与后脑运动神经元亚型的分化。  |  Osumi, N., et al. 1997. Development. 124: 2961-72. PMID: 9247338
  10. Pax-6和Cdx-2/3相互作用,激活G1控制元件上的胰高血糖素基因表达。  |  Ritz-Laser, B., et al. 1999. J Biol Chem. 274: 4124-32. PMID: 9933606

订购信息

产品名称产品编号规格价格数量收藏夹

Pax-6 抗体 (AD2.38)

sc-32766
200 µg/ml
RMB2377.00

Pax-6 (AD2.38): m-IgGλ BP-HRP 套装

sc-520859
200 µg Ab, 40 µg BP
RMB2662.00

Pax-6 抗体 (AD2.38) X

sc-32766 X
200 µg/0.1 ml
RMB2377.00

Pax-6 抗体 (AD2.38) AC

sc-32766 AC
500 µg/ml, 25% agarose
RMB3129.00

Pax-6 抗体 (AD2.38) HRP

sc-32766 HRP
200 µg/ml
RMB2377.00

Pax-6 抗体 (AD2.38) FITC

sc-32766 FITC
200 µg/ml
RMB2482.00

Pax-6 抗体 (AD2.38) PE

sc-32766 PE
200 µg/ml
RMB2580.00

Pax-6 抗体 (AD2.38) Alexa Fluor® 488

sc-32766 AF488
200 µg/ml
RMB2685.00

Pax-6 抗体 (AD2.38) Alexa Fluor® 546

sc-32766 AF546
200 µg/ml
RMB2685.00

Pax-6 抗体 (AD2.38) Alexa Fluor® 594

sc-32766 AF594
200 µg/ml
RMB2685.00

Pax-6 抗体 (AD2.38) Alexa Fluor® 647

sc-32766 AF647
200 µg/ml
RMB2685.00

Pax-6 抗体 (AD2.38) Alexa Fluor® 680

sc-32766 AF680
200 µg/ml
RMB2685.00

Pax-6 抗体 (AD2.38) Alexa Fluor® 790

sc-32766 AF790
200 µg/ml
RMB2685.00

When should the TransCruz reagent sc-32766 X be used instead of the standard form sc-32766?

Asked by: Trav11
Thank you for your question. We recommend using the TransCruz reagent form when performing ChIP or GelShift assays. This form can also be used in other applications such as Western Blot or IHC, but the dilution should be adjusted by a factor of 10 to account for the higher original concentration.
Answered by: Technical Support
Date published: 2017-02-24
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Rated 4 out of 5 by from good resultIt works very well for ImmunoFluorescence. Clear and clean signal
Date published: 2022-01-14
Rated 5 out of 5 by from Great antibodiesThe teacher bought this antibody a week ago. The effect is very good after use. He is very satisfied with the experimental results and will buy it again.
Date published: 2021-08-09
Rated 5 out of 5 by from 很出色的抗体一周前订购的该抗体,试验很顺利,结果老师也很满意,会就继续支持Santa抗体!会就继续支持Santa抗体!
Date published: 2021-08-09
Rated 1 out of 5 by from Wrong size band detectedGot this as a trial sample having trouble using an antibody from a different company. It only detects one band which unfortunately is completely the wrong size than the expected (~50)
Date published: 2018-03-23
Rated 5 out of 5 by from Good choice for Western blotStrong and clean antibody for Western blot detection of Pax-6.
Date published: 2017-01-30
Rated 4 out of 5 by from Various publishable data in WB using mouseVarious publishable data in WB using mouse pancreatic islet cells and brain tissue. -SCBT Publication Review
Date published: 2015-02-13
Rated 4 out of 5 by from Various publishable data in IHC(P) usingVarious publishable data in IHC(P) using mouse retina and embryos. -SCBT Publication Review
Date published: 2015-01-31
Rated 4 out of 5 by from Worked with transfected lysate by WBWorked with transfected lysate by WB -SCBT QC
Date published: 2015-01-23
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Pax-6 抗体 (AD2.38) is rated 4.0 out of 5 by 9.
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