Date published: 2025-9-7

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p-PDGF Receptor beta/PDGFRB 抗体 (H-3): sc-365465

5.0(1)
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说明书
  • p-PDGF Receptor beta/PDGFRB抗体(H-3)是小鼠单克隆IgG3 κ, 在1篇文献中引用,规格为200 µg/ml
  • 推荐用于 mouse, rat 和 human 来源的Tyr 716 phosphorylated PDGFR-β WB, IP, IF 和 ELISA检测
  • m-IgG3 BP-HRP是p-PDGF Receptor beta/PDGFRB Antibody (H-3) 适用于 WB 应用。 的首选辅助检测试剂,该试剂现与p-PDGF Receptor beta/PDGFRB Antibody (H-3) 搭配使用(请参阅下面的订购信息)。

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血小板源性生长因子(PDGF)是一种对间充质和神经胶质来源细胞具有促有丝分裂作用的因子。PDGF由A和B两条链组成,这两条链可二聚化形成功能不同的异构体,即PDGF-AA、PDGF-AB和PDGF-BB。这三种异构体以不同的亲和力与α和β两种受体类型结合,这两种受体都具有蛋白酪氨酸激酶结构域,并且由于配体的结合而发生同源或异源二聚化。配体刺激PDGFR-β会导致Tyr 857(主要自磷酸化位点)和Tyr 751(主要体外磷酸化位点)的自磷酸化。位于激酶插入区的Tyr 751的自磷酸化对于磷脂酰肌醇-3激酶与受体的结合是必需的。这些自磷酸化事件在很大程度上促进了通过PDGF受体的信号转导。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

p-PDGF Receptor beta/PDGFRB 抗体 (H-3)

sc-365465
200 µg/ml
RMB2377.00

p-PDGF Receptor beta/PDGFRB (H-3): m-IgG3 BP-HRP 套装

sc-550428
200 µg Ab; 40 µg BP
RMB2662.00

p-PDGF Receptor beta/PDGFRB (H-3) 中和勝肽

sc-365465 P
100 µg/0.5 ml
RMB511.00

Hi, what phopho-tyrosine on the PDGFRb does this antibody target? Y716? Y751? Y771? Y740? Y857? Y1009? Y1021?

Asked by: Stef
Thank you for your question. Tyr 716 phosphorylated PDGFR-β
Answered by: BlakeJ
Date published: 2025-04-11

What application is the blocking peptide sc-365465 P appropriate for?

Asked by: jerojero
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-27
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Rated 5 out of 5 by from Works great for Western with PDGFP beta wholeWorks great for Western with PDGFP beta whole cell lysates. -SCBT QC
Date published: 2014-03-29
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p-PDGF Receptor beta/PDGFRB 抗体 (H-3) is rated 5.0 out of 5 by 1.
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