Date published: 2025-9-8

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p-CD88 抗体 (32-G1): sc-53793

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说明书
  • p-CD88抗体(32-G1)是小鼠单克隆IgG1 κ, 在1篇文献中引用,规格为200 µg/ml
  • 针对人工合成的CD88,对应于18 C末端氨基酸,在human的CD88的丝氨酸332、334和338处被磷酸化
  • 推荐用于 human 来源的Ser 334 phosphorylated CD88 WB, IP 和 IF检测
  • m-IgG Fc BP-HRP是p-CD88 Antibody (32-G1) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与p-CD88 Antibody (32-G1) 搭配使用(请参阅下面的订购信息)。

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関連項目

CD88,也称为C5a受体(C5aR),是一种G蛋白偶联的整合膜蛋白。 CD88在中性粒细胞、单核细胞、巨噬细胞、肝细胞和肥大细胞上表达,也在各种上皮细胞和内皮细胞上表达。 CD88是炎性肽C5a的受体。 C5a与CD88的结合已被证明可引起肝脏中急性期蛋白的增加。在脑中,CD88的增加与炎症有关。 p-CD88在丝氨酸332、334和338处磷酸化。结合C5a后,CD88在C末端区域存在的丝氨酸残基上迅速磷酸化,紧接着是脱敏和内化。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

p-CD88 抗体 (32-G1) 参考文献:

  1. 人类 C5a 无乳毒素的趋化受体。  |  Gerard, NP. and Gerard, C. 1991. Nature. 349: 614-7. PMID: 1847994
  2. 拟杆菌毒素:C3a 和 C5a。  |  Hugli, TE. and Müller-Eberhard, HJ. 1978. Adv Immunol. 26: 1-53. PMID: 358800
  3. 人类嗜碱性粒细胞和肥大细胞上补体受体的差异表达。肥大细胞异质性和皮肤肥大细胞上 CD88/C5aR 表达的证据。  |  Füreder, W., et al. 1995. J Immunol. 155: 3152-60. PMID: 7673728
  4. C5a 无噬菌体毒素受体(C5aR)的细胞表达:肝脏和肺部非髓细胞上的 C5aR 演示。  |  Haviland, DL., et al. 1995. J Immunol. 154: 1861-9. PMID: 7836770
  5. 检测人嗜酸性粒细胞上的 C5a 受体以及抗 C5a 受体 (CD88) 抗体对嗜酸性粒细胞效应功能的抑制。  |  Elsner, J., et al. 1996. Eur J Immunol. 26: 1560-4. PMID: 8766561
  6. 在发炎的人类中枢神经系统中,反应性星形胶质细胞, 小胶质细胞和内皮细胞的补体 C5a 受体(CD88)表达上调。  |  Gasque, P., et al. 1997. Am J Pathol. 150: 31-41. PMID: 9006319

订购信息

产品名称产品编号规格价格数量收藏夹

p-CD88 抗体 (32-G1)

sc-53793
200 µg/ml
RMB2377.00

p-CD88 (32-G1): m-IgG Fc BP-HRP 套装

sc-539004
200 µg Ab; 10 µg BP
RMB2662.00

I'm looking for an antibidy against p-CD88. Can I use this one or do you have the product out of catalog ? Thank you

Asked by: Auré
Thank you for your question. This antibody is available and can be supplied. Please contact our European support and sales office for a quotation or to place an order.
Answered by: Tech Support Europe
Date published: 2023-09-18

I am using the LiCor/Odyssey system. Which secondary antibody do you recommend using with p-CD88 (32-G1): sc-53793?

Asked by: cjMara
We recommend using one of our our exclusive Mouse IgG Binding Proteins conjugated to CFL 680 or CFL 790. They are suitable for use with Near-Infrared (NIR) detection systems, such as LI-COR/Odyssey and other comparable systems. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support
Date published: 2017-02-27
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Rated 3 out of 5 by from Robust signal in WB in human transfectedRobust signal in WB in human transfected 293T whole cell lysates. -SCBT QC
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p-CD88 抗体 (32-G1) is rated 3.0 out of 5 by 1.
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