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Oviductin Antibody (G-7) - Western Blotting - Image 155064
输卵管蛋白抗体 (G-7): sc-376300. Hep G2 全细胞裂解液中输卵管蛋白表达的 Western 印迹分析.
输卵管蛋白抗体 (G-7): sc-376300. Hep G2 全细胞裂解液中输卵管蛋白表达的 Western 印迹分析.

Oviductin 抗体 (G-7): sc-376300

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说明书
  • Oviductin抗体(G-7)是小鼠单克隆IgM (kappa轻链)，规格为200 µg/ml
  • 特异性抗原位于human物种的Oviductin (also designated Mucin 9)的C-terminus附近的氨基酸621-659之间
  • 推荐用于 human 来源的Oviductin WB, IP, IF, IHC(P) 和 ELISA检测
  • 目前，我们还没有完成Oviductin 抗体 (G-7)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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    描述
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    说明书与实验方案
    研究信息

    関連項目

    粘蛋白是一类高度糖基化的分泌蛋白，其基本结构由可变数量的串联重复序列(VNTRs)组成。重复序列的数量具有高度多态性，并在不同等位基因之间变化。粘蛋白家族包括粘蛋白1-4、粘蛋白5（AC和B）、粘蛋白6-8、粘蛋白11-13和粘蛋白15-17。粘蛋白9（Muc9），通常被称为输卵管特异性糖蛋白（Oviductin）或雌激素依赖性输卵管蛋白，是一种输卵管特异性蛋白。它在体内与卵母细胞透明带结合，并参与受精过程和早期胚胎发育。Oviductin定位于分泌颗粒中，在OE-E6/E7细胞系中可检测到该蛋白。在人类生殖周期中，Oviductin的表达在排卵时最高。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    Oviductin 抗体 (G-7) 参考文献:

    1. 人类输卵管蛋白 mRNA 的表达在输卵管粘膜细胞培养中无法维持。  |  Briton-Jones, C., et al. 2002. Fertil Steril. 77: 576-80. PMID: 11872215
    2. 输卵管蛋白 mRNA 在人类生殖周期不同阶段的不同表达。  |  Lok, IH., et al. 2002. J Assist Reprod Genet. 19: 569-76. PMID: 12503889
    3. 人类绒毛膜促性腺激素和17-β雌二醇对体外人类输卵管蛋白/输卵管特异性糖蛋白mRNA表达的调节。  |  Briton-Jones, C., et al. 2003. Fertil Steril. 80 Suppl 2: 720-6. PMID: 14505745
    4. 雌二醇对体外人类输卵管粘膜细胞中输卵管素/输卵管特异性糖蛋白信使核糖核酸表达的调节。  |  Briton-Jones, C., et al. 2004. Fertil Steril. 81 Suppl 1: 749-56. PMID: 15019805
    5. 人类输卵管蛋白在永生化人类输卵管细胞系中的表达。  |  Ling, L., et al. 2005. Fertil Steril. 84 Suppl 2: 1095-103. PMID: 16209999
    6. 水牛（Bubalus bubalis）输卵管特异性糖蛋白在大肠杆菌中的分子克隆、序列表征和异源表达。  |  Janjanam, J., et al. 2012. Mol Biol Rep. 39: 10031-43. PMID: 22782592
    7. 重组人卵导管蛋白调节蛋白酪氨酸磷酸化反应和顶体反应。  |  Zhao, Y., et al. 2016. Reproduction. 152: 561-573. PMID: 27581080
    8. 受孕期输卵管环境的比较研究。  |  González-Brusi, L., et al. 2020. Biomolecules. 10: PMID: 33348856
    9. 作为炎症性疾病治疗靶点的几丁质酶和几丁质酶样蛋白，特别关注炎症性肠病。  |  Mazur, M., et al. 2021. Int J Mol Sci. 22: PMID: 34203467
    10. 人类输卵管液蛋白。V. 人类输卵管蛋白-I作为甲胎蛋白的鉴定。  |  Wagh, PV. and Lippes, J. 1993. Fertil Steril. 59: 148-56. PMID: 7678232

    订购信息

    产品名称产品编号规格价格数量收藏夹

    Oviductin 抗体 (G-7)

    sc-376300
    200 µg/ml
    		RMB2377.00

    Oviductin (G-7) 中和勝肽

    sc-376300 P
    100 µg/0.5 ml
    		RMB511.00

    Oviductin, or OVGP1is known to be specifically expressed by the secretory cells of the oviductal epithelium and not expressed in normal ovarian tissue or ovarian oocytes. What ovarian tissue have you used for detect oviductin expression?

    Asked by: SallyZh
    Thank you for your question. At the time this testing was performed, Source said that >75% of OVGP1 expression happened in ovary. A current review on HPA shows no expression in ovary. We will have our lab review this IHC(P) data. In the meantime, please consider this alternative, Oviductin Antibody (H-8): sc-377267, which has more recent data in formalin fixed, paraffin-embedded human fallopian tube.
    Answered by: Technical Support
    Date published: 2019-07-12

    What application is the blocking peptide sc-376300 P appropriate for?

    Asked by: Professor Griffin
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-25
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    Rated 5 out of 5 by from goodProtein is a highly glycosylated family of secreted proteins with a basic structure consisting of a variable number of tandem repeats that can be found in the literature, usually called tubal-specific glycoproteins or estrogen-dependent tubal proteins, which are tubal-specific proteins.
    Date published: 2017-02-08
    Rated 5 out of 5 by from detect the expression of OVNOviductin (Ovn) plays crucial role during fertilization and early embryonic development. We knock down the corresponding gene to research its function. We found this antibody can detect the decrease expression of OVN in animal.
    Date published: 2016-12-18
    Rated 5 out of 5 by from Produced exceptional immunoperoxidase cytoplasmicProduced exceptional immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human ovary tissue. -SCBT QC
    Date published: 2015-05-20
    Rated 5 out of 5 by from Nice Western Blot data of Oviductin expressionNice Western Blot data of Oviductin expression in Hep G2 whole cell lysate. -SCBT QC
    Date published: 2013-01-28
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    Oviductin抗体 (G-7) is rated 5.0 out of 5 by 4.
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