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Oct-2 Antibody (D-12) - Western Blotting - Image 285014 — Oct-2 抗体 (D-12): sc-365116. 拉莫斯 (A) 和拉吉 (B) 全细胞裂解液中 Oct-2B 表达的 Western 印迹分析.

Oct-2 抗体 (D-12): sc-365116. 拉莫斯 (A) 和拉吉 (B) 全细胞裂解液中 Oct-2B 表达的 Western 印迹分析.

Oct-2 抗体 (D-12): sc-365116

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寫評論提問

说明书

Oct-2抗体(D-12)是小鼠单克隆IgM κ, 在2篇文献中引用，规格为200 µg/ml
特异性抗原位于human物种的Oct-2的C-terminus的氨基酸435-463之间
推荐用于 mouse, rat 和 human 来源的Oct-2 WB, IP, IF 和 ELISA检测; 也和以下物种反应，包括： canine
可用于ChIP的TransCruz试剂(sc-365116 X, 200 µg/0.1 ml)
看 Oct-2 (PT2): sc-56822，可查看有标记的 Oct-2 抗体，包括AC, HRP, FITC, PE, Alexa Fluor^® 488, 594, 647, 680 和 790
m-IgGκ BP-HRP是Oct-2 Antibody (D-12) 适用于 WB 应用。的首选辅助检测试剂。该试剂现可与Oct-2 Antibody (D-12) 搭配使用（请参阅下面的订购信息）。有关其它 m-IgGκ BP 结合物，请参阅我们完整的小鼠 IgG 结合蛋白列表。

查看产品引用文献(2)

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Oct-2 抗体 (D-12) 参考文献:

Transport of drugs in the kidney by the human organic cation transporter, OCT2 and its genetic variants. | Fujita, T., et al. 2006. J Pharm Sci. 95: 25-36. PMID: 16307453
OCT-2表达和OCT-2/BOB.1共表达可预测新诊断急性髓细胞白血病患者的预后。 | Advani, AS., et al. 2010. Leuk Lymphoma. 51: 606-12. PMID: 20141429
八聚体结合蛋白 Oct-1 和 Oct-2 对 HMGA1 基因的转录调控。 | Chiefari, E., et al. 2013. PLoS One. 8: e83969. PMID: 24367622
Oct-2与Oct-1在乳腺上皮细胞中转录激活泌乳激素诱导的β-酪蛋白基因表达过程中的协同作用 | Qian, X. and Zhao, FQ. 2014. Gen Comp Endocrinol. 204: 185-94. PMID: 24861805
抗呕吐药体外抑制肾OCT2和MATE1分泌。 | George, B., et al. 2021. Int J Mol Sci. 22: PMID: 34208557
药物间相互作用和药物对肾有机阳离子转运体2（OCT2）和多药和毒素排除1、2-K（MATE1/MATE2-K）的肾毒性的临床研究。 | Saad, AAA., et al. 2022. Biol Pharm Bull. 45: 382-393. PMID: 35370262
Rosai-Dorfman病中转录因子PU.1和Oct-2的强共表达。 | Kiruthiga, KG., et al. 2022. Am J Clin Pathol. 158: 672-677. PMID: 36239684
根据建模方法，在联合使用福司他韦的情况下，二甲双胍或有机阳离子转运体（OCT）1和OCT2以及多药和毒素排出蛋白（MATE）1/2K的底物无需调整剂量。 | Nguyen, D., et al. 2024. Pharmacol Res Perspect. 12: e1238. PMID: 38988092
Oct-1 [corrected] and Oct-2 DNA-binding site specificity is regulated in vitro by different kinases. | Grenfell, SJ., et al. 1996. Biochem J. 315 (Pt 3): 889-93. PMID: 8645173
使用改变特异性的Oct-1和Oct-2突变体来分析免疫球蛋白基因转录的调控。 | Shah, PC., et al. 1997. EMBO J. 16: 7105-17. PMID: 9384588

种属	基因名称	基因ID	染色体位置	亚型（mRNA）登录号	蛋白质登录号	OMIM™ 号码
Human	POU2F2	Entrez Gene ID: 5452	19q13.2	XM_005259010, XM_011527040, XM_011527041, XM_011527042, XM_011527043, XM_017026884, XM_017026885, XM_017026886, XM_017026887, XM_017026888, XM_017026889, XM_017026890, XM_017026891, XM_017026892, XM_017026893, XM_017026894, XM_017026895, XM_017026896, NM_001207025, NM_001207026, NM_001247994, NM_002698	UniProt ID: P09086	164176
Mouse	Pou2f2	Entrez Gene ID: 18987	7 A3	XM_006539647, XM_006539648, XM_006539649, XM_006539650, XM_006539651, XM_006539652, XM_006539653, XM_006539654, XM_006539655, XM_006539656, XM_006539658, XM_006539659, XM_006539660, XM_006539661, XM_006539662, XM_011250457, NM_001163554, NM_001163555, NM_001163556, NM_011138	UniProt ID: Q00196	N/A

订购信息

产品名称	产品编号	规格	价格	数量	收藏夹
Oct-2 抗体 (D-12)	sc-365116	200 µg/ml	CNY2422.00
Oct-2 (D-12): m-IgGκ BP-HRP 套装	sc-552336	200 µg Ab; 40 µg BP	CNY2715.00
Oct-2 (D-12) 中和勝肽	sc-365116 P	100 µg/0.5 ml	CNY519.00
Oct-2 抗体 (D-12) X	sc-365116 X	200 µg/0.1 ml	CNY2422.00

Could I please ask which specific kappa chain makes up this antibody? It seems that only VκI light chains can be immunoprecipitated by protein L beads. Thank you!

Asked by: Michael_Lee

Thank you for your question. I can confirm that this antibody has a kappa light chain. I do not have further information on which specific kappa chain it is. If you have any further questions, please contact Technical Service or reach out to your local distributor.

Answered by: Tech Service

Date published: 2019-11-25

What application is the blocking peptide sc-365116 P appropriate for?

Asked by: TinTin

Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization

Answered by: Technical Support

Date published: 2017-02-28

Rated 5 out of 5 by Navaz from OCT2 antibodyExcellent antibody for both human and rat renal tissues. I used it for western blot.

Date published: 2019-06-07

Rated 5 out of 5 by TS from Good antibody for westernGood antibody for western, clean background and specific band in Ramos and Raji whole cell lysates. -SCBT QC

Date published: 2015-04-10

Rated 5 out of 5 by LM from Works well for IF applicationsWorks well for IF applications, positive in HeLa. -SCBT QC

Date published: 2015-02-03

Rated 5 out of 5 by LF from Good antibody for westernGood antibody for western, specific band in Raji whole cell lysate. -SCBT QC

Date published: 2015-01-22

Oct-2 抗体 (D-12) is rated 5.0 out of 5 by 4.

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Oct-2 抗体 (D-12): sc-365116

Oct-2 抗体 (D-12) 参考文献:

優選的 Oct-2 抗體是 Oct-2 抗體 (PT2): sc-56822.

Oct-2 抗体 (D-12)

Oct-2 (D-12): m-IgGκ BP-HRP 套装

Oct-2 (D-12) 中和勝肽

Oct-2 抗体 (D-12) X

Could I please ask which specific kappa chain makes up this antibody? It seems that only V&kappa;I light chains can be immunoprecipitated by protein L beads. Thank you!

What application is the blocking peptide sc-365116 P appropriate for?

Could I please ask which specific kappa chain makes up this antibody? It seems that only VκI light chains can be immunoprecipitated by protein L beads. Thank you!