Date published: 2025-9-8

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NTR1 抗体 (G-9): sc-393205

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说明书
  • NTR1抗体(G-9)是小鼠单克隆IgG2b κ, 在1篇文献中引用,规格为200 µg/ml
  • 免疫human物种的NTR1的氨基酸181-310
  • 推荐用于 mouse, rat 和 human 来源的NTR1 WB, IP, IF, IHC(P) 和 ELISA检测
  • m-IgG Fc BP-HRPm-IgGκ BP-HRP 是 NTR1 抗体 (G-9) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与NTR1 抗体 (G-9) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

神经降压素(NT)通过与G蛋白偶联受体NTR1(NTS1受体,高亲和力NTR)和NTR2(NTS2受体,左卡巴斯汀敏感性神经降压素受体)以及I型受体NTR3(NTS3受体,sortilin-1,Gp95)相互作用,引发细胞内反应。神经降压素在大脑区域和外周组织中广泛分布,其中神经降压素受体可导致低血压、高血糖、低温、抗伤害感受以及调节肠道运动和分泌。HL-60细胞表达NTR1,该细胞可与Gq、Gi/o或Gs偶联。大鼠NTR2的选择性剪接可产生一种具有五个跨膜结构域的变异体,该变异体与全长NTR2在整个大脑和脊髓中共表达。在小鼠小胶质细胞系N11中,NTR3的激活以ERK1/2和Akt激酶依赖的方式诱导MIP-2、MCP-1、IL-1b和TNFa。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

NTR1 抗体 (G-9) 参考文献:

  1. HL-60 细胞中高亲和性神经肽受体 NTR1 的特征及其在粒细胞分化过程中的下调作用。  |  Choi, SY., et al. 1999. Br J Pharmacol. 126: 1050-6. PMID: 10193787
  2. 删除小鼠神经紧张素受体 NTR1 对神经紧张素中枢和外周反应的影响  |  Pettibone, DJ., et al. 2002. J Pharmacol Exp Ther. 300: 305-13. PMID: 11752130
  3. NTR1 和 NTR2 神经紧张素受体之间的分子间交叉作用促进了 NTR1 受体的胞内封闭和功能抑制。  |  Hwang, JR., et al. 2010. Biochem Biophys Res Commun. 391: 1007-13. PMID: 19968961
  4. 人胰腺癌细胞株中 NTR1 和表皮生长因子受体的相对表达与细胞密度和细胞外 pH 值的关系  |  Olszewski-Hamilton, U. and Hamilton, G. 2011. Cancers (Basel). 3: 182-97. PMID: 24212612
  5. 神经紧张素受体 1 可促进大分子在细胞内和经上皮细胞输送。  |  Bird, JL., et al. 2017. Eur J Pharm Biopharm. 119: 300-309. PMID: 28690201
  6. 分离和鉴定噬菌体 NTR1 对横纹诺卡氏菌和其他诺卡氏菌具有传染性。  |  Taylor, S., et al. 2019. Virus Genes. 55: 257-265. PMID: 30560472
  7. 非enotoxic 3-硝基咪唑并[1,2-a]吡啶是 NTR1 的底物,在体外显示出强大的抗利什曼病活性。  |  Fersing, C., et al. 2019. ACS Med Chem Lett. 10: 34-39. PMID: 30655943
  8. 神经紧张素受体 1 激动剂为糖尿病前期大鼠提供神经保护  |  Saiyasit, N., et al. 2021. J Endocrinol. 248: 59-74. PMID: 33112810
  9. 原发性乳腺肿瘤中神经营养素受体-1(NTS1)的表达, 细胞分布以及与临床和生物学因素的关系。  |  Morgat, C., et al. 2021. Breast Cancer Res Treat. 190: 403-413. PMID: 34596798
  10. 揭示神经肽受体 1 识别神经肽的机制。  |  Asadollahi, K., et al. 2023. Nat Commun. 14: 8155. PMID: 38071229

订购信息

产品名称产品编号规格价格数量收藏夹

NTR1 抗体 (G-9)

sc-393205
200 µg/ml
RMB2377.00

NTR1 (G-9): m-IgG Fc BP-HRP 套装

sc-538167
200 µg Ab; 10 µg BP
RMB2662.00

NTR1 (G-9): m-IgGκ BP-HRP 套装

sc-535727
200 µg Ab; 40 µg BP
RMB2662.00

The molecular weight of NTSR1 is supposed to be 46kDa.Based on the data of your product the band size does not match for the NTSR1. Figure 1 is smaller than 46kDA, and the Figure 2 is much larger than 46kDa. Why is this so different?

Asked by: Sook
Thank you for your inquiry. Please contact our Technical Service Department. Our Asian Technical Service team is available at (+86) 021-60936350 or [email protected] or by live chat on our website. 당신의 문의에 감사드립니다.저희 기술 서비스 부서에 문의하십시오.아시아 기술 서비스 팀은 (+86) 021-60936350 또는 [email protected] 또는 웹 사이트에서 라이브 채팅을 통해 이용할 수 있습니다.
Answered by: Yanru Tao
Date published: 2024-07-30

Can this antibody be used to detect NTR1 of rat origin?

Asked by: AbPolly
Thank you for your question. Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Service
Date published: 2017-01-27
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Rated 5 out of 5 by from Excellent choice ab for detecting NTR1 in WBstrong WB bands in EOC 20 whole cell lysate and mouse cerebellum and mouse brain tissue extracts.
Date published: 2016-12-29
Rated 5 out of 5 by from Produced positive Western blot data of NTR1Produced positive Western blot data of NTR1 expression in IMR-32 and T98G whole cell lysates. -SCBT QC
Date published: 2013-07-09
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NTR1 抗体 (G-9) is rated 5.0 out of 5 by 2.
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