Norethisterone Acetate (CAS 51-98-9)

外观 :

Powder

物理状态 :

Solid

溶解度 :

Soluble in chloroform, DMSO, and methanol.

保存 :

Store at room temperature

熔点 :

161-162° C

沸点 :

454.70° C

密度 :

~1.1 g/cm³ (Predicted)

折射率 :

n²⁰_D 1.56 (Predicted)

光学活性 :

α20_D -33.5°±1.5°, c = 1 in dioxane

IC50 :

Progesterone receptor: IC₅₀ = 28 nM (bos taurus); Androgen Receptor: IC₅₀ = 106 nM (rat); Glucocorticoid receptor: IC₅₀ = 646 nM (human); Cytochrome P450 2C19: IC₅₀ = 800 nM (human)

Ki 数据 :

Progesterone receptor: K_i= 3.62 nM (bos taurus); Androgen Receptor: K_i= 71 nM (rat); Glucocorticoid receptor: K_i= 293 nM (human)

RTECS :

RC8965000

PubChem CID :

MDL 号码 :

MFCD00271615

EC号码 :

200-132-0

SMILES :

CC(=O)O[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@H]34)C)C#C